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M. N. Lavanya, R. Preethi, J. A. Moses & C. Anandharamakrishnan. (2022) Aerosol-based Pulmonary Delivery of Therapeutic Molecules from Food Sources: Delivery Mechanism, Research Trends, and the Way Forward. Food Reviews International 38:sup1, pages 753-788.
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Mengyang Liu, Shuo Chen, Zhiwen Zhang, Hongyu Li, Guiju Sun, Naibo Yin & Jingyuan Wen. (2022) Anti-ageing peptides and proteins for topical applications: a review. Pharmaceutical Development and Technology 27:1, pages 108-125.
Read now
Read now
Qi-en Che, Peng Quan, Mao Mu, Xinfu Zhang, Hanqing Zhao, Yu Zhang, Song You, Yi Xiao & Liang Fang. (2014) Enantioselective skin permeation of ibuprofen enantiomers: mechanistic insights from ATR-FTIR and CLSM studies based on synthetic enantiomers as naphthalimide fluorescent probes. Expert Opinion on Drug Delivery 11:10, pages 1513-1523.
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Sarah Küchler, Kay Strüver & Wolfgang Friess. (2013) Reconstructed skin models as emerging tools for drug absorption studies. Expert Opinion on Drug Metabolism & Toxicology 9:10, pages 1255-1263.
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Articles from other publishers (62)
Greta Camilla Magnano, Marika Quadri, Elisabetta Palazzo, Roberta Lotti, Francesca Loschi, Stefano Dall'Acqua, Michela Abrami, Francesca Larese Filon, Alessandra Marconi & Dritan Hasa. (2024) 3D human foreskin model for testing topical formulations of sildenafil citrate. International Journal of Pharmaceutics 649, pages 123612.
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Crossref
Johanna Maria Hölken, Katja Friedrich, Marion Merkel, Nelli Blasius, Ursula Engels, Timo Buhl, Karsten Rüdiger Mewes, Lars Vierkotten & Nicole Elisabeth Teusch. (2023) A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation. Frontiers in Immunology 14.
Crossref
Crossref
William Mason, Albert M. Levin, Katherine Buhl, Takahiro Ouchi, Bianca Parker, Jessica Tan, Nureddin Ashammakhi & Lamont R Jones. (2023) Translational Research Techniques for the Facial Plastic Surgeon: An Overview. Facial Plastic Surgery.
Crossref
Crossref
Nicole Esposto Biondo, Débora Fretes Argenta & Thiago Caon. (2023) A Comparative Analysis of Biological and Synthetic Skin Models for Drug Transport Studies. Pharmaceutical Research 40:5, pages 1209-1221.
Crossref
Crossref
Liza Józsa, Dániel Nemes, Ágota Pető, Dóra Kósa, Réka Révész, Ildikó Bácskay, Ádám Haimhoffer & Gábor Vasvári. (2023) Recent Options and Techniques to Assess Improved Bioavailability: In Vitro and Ex Vivo Methods. Pharmaceutics 15:4, pages 1146.
Crossref
Crossref
Richard W. J. Helder, Jannik Rousel, Walter A. Boiten, Gerrit S. Gooris, Andreea Nadaban, Abdoelwaheb El Ghalbzouri & Joke A. Bouwstra. (2023)
The effect of
PPAR
isoform (de)activation on the lipid composition in full‐thickness skin models
. Experimental Dermatology 32:4, pages 469-478.
Crossref
Crossref
Jinchul Ahn, Kyungeun Ohk, Jihee Won, Dong-Hee Choi, Yong Hun Jung, Ji Hun Yang, Yesl Jun, Jin-A Kim, Seok Chung & Sang-Hoon Lee. (2023) Modeling of three-dimensional innervated epidermal like-layer in a microfluidic chip-based coculture system. Nature Communications 14:1.
Crossref
Crossref
Antonio José Guillot, Miquel Martínez-Navarrete, Teresa M. Garrigues & Ana Melero. (2023) Skin drug delivery using lipid vesicles: A starting guideline for their development. Journal of Controlled Release 355, pages 624-654.
Crossref
Crossref
Qiwei Li, Chunyan Wang, Xiaoran Li, Jing Zhang, Zilin Zhang, Keyu Yang, Jun Ouyang, Shaohui Zha, Lifeng Sha, Jianjun Ge, Zaozao Chen & Zhongze Gu. (2023) Epidermis-on-a-chip system to develop skin barrier and melanin mimicking model. Journal of Tissue Engineering 14, pages 204173142311685.
Crossref
Crossref
Hassan Srour, Alexis Gosset, François-Marie Moussallieh, Karim Elbayed, Elena Giménez-Arnau & Jean-Pierre Lepoittevin. (2022)
Synthesis and
In Situ
Behavior of 1,4- and 2,5-(
13
C) Isotopomers of
p-
Phenylenediamine in Reconstructed Human Epidermis Using High Resolution Magic Angle Spinning NMR
. Chemical Research in Toxicology 35:10, pages 1881-1892.
Crossref
Crossref
Nicole Kornbausch, Marcel W. Debong, Andrea Buettner, Jean‐Marie Heydel & Helene M. Loos. (2022) Odorant Metabolism in Humans. Angewandte Chemie International Edition 61:35.
Crossref
Crossref
Nicole Kornbausch, Marcel W. Debong, Andrea Buettner, Jean‐Marie Heydel & Helene M. Loos. (2022) Geruchsstoffmetabolismus im Menschen. Angewandte Chemie 134:35.
Crossref
Crossref
Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah & Stuart Harrad. (2022) Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?. Environmental Pollution 307, pages 119478.
Crossref
Crossref
Estibaliz Fernandez-Carro, Maricke Angenent, Tamara Gracia-Cazaña, Yolanda Gilaberte, Clara Alcaine & Jesús Ciriza. (2022) Modeling an Optimal 3D Skin-on-Chip within Microfluidic Devices for Pharmacological Studies. Pharmaceutics 14:7, pages 1417.
Crossref
Crossref
A.A. Amarah, J. Hadgraft, M.S. Roberts & Y.G. Anissimov. (2022) Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics 623, pages 121902.
Crossref
Crossref
Ilaria Pulsoni, Markus Lubda, Maurizio Aiello, Arianna Fedi, Monica Marzagalli, Joerg von Hagen & Silvia Scaglione. (2022) Comparison Between Franz Diffusion Cell and a novel Micro-physiological System for In Vitro Penetration Assay Using Different Skin Models. SLAS Technology 27:3, pages 161-171.
Crossref
Crossref
Karolina Słoczyńska, Justyna Popiół, Agnieszka Gunia-Krzyżak, Paulina Koczurkiewicz-Adamczyk, Paweł Żmudzki & Elżbieta Pękala. (2022) Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model EpiskinTM: Perspectives for Application as Potential Sunscreen Agents. Molecules 27:6, pages 1850.
Crossref
Crossref
A. Ali, L. Ringstad, L. Skedung, P. Falkman, M. Wahlgren & J. Engblom. (2022) Tactile friction of topical creams and emulsions: Friction measurements on excised skin and VitroSkin® using ForceBoard™. International Journal of Pharmaceutics 615, pages 121502.
Crossref
Crossref
Ayesha Sadaf, Rajeshwari Sinha & Mary K. Ekka. (2022) Ionic liquid-mediated skin technologies: Recent advances and prospects. Current Research in Biotechnology 4, pages 514-529.
Crossref
Crossref
Suryanarayana Polaka, Priyanka Pulugu, Muktika Tekade, Mukesh Chandra Sharma & Rakesh Kumar Tekade. 2022. Pharmacokinetics and Toxicokinetic Considerations. Pharmacokinetics and Toxicokinetic Considerations
385
400
.
Fátima Pinto, Luis P. Fonseca & Dragana P. C. de Barros. 2022. Nanotoxicology in Safety Assessment of Nanomaterials. Nanotoxicology in Safety Assessment of Nanomaterials
83
114
.
Mingyue Cui, Christian Wiraja, Mengjia Zheng, Gurvinder Singh, Ken‐Tye Yong & Chenjie Xu. (2021) Recent Progress in Skin‐on‐a‐Chip Platforms. Advanced Therapeutics 5:1, pages 2100138.
Crossref
Crossref
Zsófia Varga-Medveczky, Dorottya Kocsis, Márton Bese Naszlady, Katalin Fónagy & Franciska Erdő. (2021) Skin-on-a-Chip Technology for Testing Transdermal Drug Delivery—Starting Points and Recent Developments. Pharmaceutics 13:11, pages 1852.
Crossref
Crossref
I. Risueño, L. Valencia, J. L. Jorcano & D. Velasco. (2021) Skin-on-a-chip models: General overview and future perspectives. APL Bioengineering 5:3.
Crossref
Crossref
Raquel Costa, Sofia A. Costa Lima, Paula Gameiro & Salette Reis. (2021) On the Development of a Cutaneous Flavonoid Delivery System: Advances and Limitations. Antioxidants 10:9, pages 1376.
Crossref
Crossref
Arnout Mieremet, Richard W. J. Helder, Andreea Nadaban, Walter A. Boiten, Gert S. Gooris, Abdoelwaheb El Ghalbzouri & Joke A. Bouwstra. (2021) Multitargeted Approach for the Optimization of Morphogenesis and Barrier Formation in Human Skin Equivalents. International Journal of Molecular Sciences 22:11, pages 5790.
Crossref
Crossref
Richard W.J. Helder, Jannik Rousel, Walter A. Boiten, Gerrit S. Gooris, Andreea Nadaban, Abdoelwaheb El Ghalbzouri & Joke A. Bouwstra. (2021) Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting stearoyl-CoA desaturase-1. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1866:4, pages 158885.
Crossref
Crossref
J. Ponmozhi, S. Dhinakaran, Zsófia Varga-Medveczky, Katalin Fónagy, Luca Anna Bors, Kristóf Iván & Franciska Erdő. (2021) Development of Skin-On-A-Chip Platforms for Different Utilizations: Factors to Be Considered. Micromachines 12:3, pages 294.
Crossref
Crossref
Tânia Moniz, Sofia A. Costa Lima & Salette Reis. (2020) Human skin models: From healthy to disease‐mimetic systems; characteristics and applications. British Journal of Pharmacology 177:19, pages 4314-4329.
Crossref
Crossref
Rabin Neupane, Sai H.S. Boddu, Jwala Renukuntla, R. Jayachandra Babu & Amit K. Tiwari. (2020) Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities. Pharmaceutics 12:2, pages 152.
Crossref
Crossref
Hye Mi Jeon, Kyunghee Kim, Kyung Chan Choi & Gun Yong Sung. (2020) Side-effect test of sorafenib using 3-D skin equivalent based on microfluidic skin-on-a-chip. Journal of Industrial and Engineering Chemistry 82, pages 71-80.
Crossref
Crossref
S. Abadie, P. Bedos & J. Rouquette. (2019) A human skin model to evaluate the protective effect of compounds against UVA damage. International Journal of Cosmetic Science 41:6, pages 594-603.
Crossref
Crossref
Ivo J.H.M. de Vos, Julia Verbist & Maurice A.M. van Steensel. 2019. Imaging Technologies and Transdermal Delivery in Skin Disorders. Imaging Technologies and Transdermal Delivery in Skin Disorders
105
146
.
Jonathan R. Soucy, Adam J. Bindas, Abigail N. Koppes & Ryan A. Koppes. (2019) Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes. iScience 21, pages 521-548.
Crossref
Crossref
Zinaida Shakel, Cláudia Nunes, Sofia A Costa Lima & Salette Reis. (2019) Development of a novel human stratum corneum model, as a tool in the optimization of drug formulations. International Journal of Pharmaceutics 569, pages 118571.
Crossref
Crossref
Sana Suhail, Naseem Sardashti, Devina Jaiswal, Swetha Rudraiah, Manoj Misra & Sangamesh G. Kumbar. (2019) Engineered Skin Tissue Equivalents for Product Evaluation and Therapeutic Applications. Biotechnology Journal 14:7, pages 1900022.
Crossref
Crossref
Yeevon Poh, Sookhan Ng & Ketli Ho. (2019) Formulation and characterisation of 1-ethyl-3-methylimidazolium acetate-in-oil microemulsions as the potential vehicle for drug delivery across the skin barrier. Journal of Molecular Liquids 273, pages 339-345.
Crossref
Crossref
Suneel Kumar, Hwan June Kang & Francois Berthiaume. 2019. Handbook of Tissue Engineering Scaffolds: Volume Two. Handbook of Tissue Engineering Scaffolds: Volume Two
173
191
.
Ye Eun Yun, Youn Jae Jung, Yeo Jin Choi, Ji Suk Choi & Yong Woo Cho. (2018) Artificial skin models for animal-free testing. Journal of Pharmaceutical Investigation 48:2, pages 215-223.
Crossref
Crossref
Camila N. Lemos, Francieli Pereira, Luciana F. Dalmolin, Camila Cubayachi, Danielle N. Ramos & Renata F.V. Lopez. 2018. Nanostructures for the Engineering of Cells, Tissues and Organs. Nanostructures for the Engineering of Cells, Tissues and Organs
187
248
.
Yusef Yousuf, Saeid Amini-Nik & Marc G. Jeschke. 2018. Skin Tissue Models for Regenerative Medicine. Skin Tissue Models for Regenerative Medicine
39
54
.
Nadine Döge, Araks Avetisyan, Sabrina Hadam, Eva Katharina Barbosa Pfannes, Fiorenza Rancan, Ulrike Blume-Peytavi & Annika Vogt. (2017) Assessment of skin barrier function and biochemical changes of ex vivo human skin in response to physical and chemical barrier disruption. European Journal of Pharmaceutics and Biopharmaceutics 116, pages 138-148.
Crossref
Crossref
Lenie J. van den Broek, Lambert I. J. C. Bergers, Christianne M. A. Reijnders & Susan Gibbs. (2017) Progress and Future Prospectives in Skin-on-Chip Development with Emphasis on the use of Different Cell Types and Technical Challenges. Stem Cell Reviews and Reports 13:3, pages 418-429.
Crossref
Crossref
Nobuhito Mori, Yuya Morimoto & Shoji Takeuchi. (2017) Skin integrated with perfusable vascular channels on a chip. Biomaterials 116, pages 48-56.
Crossref
Crossref
Heinz Ruffner, Ursula Graf-Hausner & Stephanie Mathes. 2016. Skin Tissue Engineering and Regenerative Medicine. Skin Tissue Engineering and Regenerative Medicine
357
386
.
Monika Schäfer-Korting & Eder Lilia Romero. 2016. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
241
251
.
Mihaela D. Leonida & Ish KumarMihaela D. Leonida & Ish Kumar. 2016. Bionanomaterials for Skin Regeneration. Bionanomaterials for Skin Regeneration
47
52
.
Gøril Eide Flaten, Zora Palac, André Engesland, Jelena Filipović-Grčić, Željka Vanić & Nataša Škalko-Basnet. (2015) In vitro skin models as a tool in optimization of drug formulation. European Journal of Pharmaceutical Sciences 75, pages 10-24.
Crossref
Crossref
Coralie DumontPilar PrietoDavid AsturiolAndrew Worth. (2015)
Review of the Availability of
In Vitro
and
In Silico
Methods for Assessing Dermal Bioavailability
. Applied In Vitro Toxicology 1:2, pages 147-164.
Crossref
Crossref
André Engesland, Nataša Škalko-Basnet & Gøril Eide Flaten. (2015) Phospholipid Vesicle-Based Permeation Assay and EpiSkin® in Assessment of Drug Therapies Destined for Skin Administration. Journal of Pharmaceutical Sciences 104:3, pages 1119-1127.
Crossref
Crossref
C. Stiefel & W. Schwack. (2015) Photoprotection in changing times - UV filter efficacy and safety, sensitization processes and regulatory aspects. International Journal of Cosmetic Science 37:1, pages 2-30.
Crossref
Crossref
Gary P. Moss, Darren R. Gullick & Simon C. WilkinsonGary P. Moss, Darren R. Gullick & Simon C. Wilkinson. 2015. Predictive Methods in Percutaneous Absorption. Predictive Methods in Percutaneous Absorption
91
102
.
Bernard QuerleuxSophie Martel & Pierre-Alain Carrupt. 2014. Computational Biophysics of the Skin. Computational Biophysics of the Skin
243
288
.
Stephanie H. Mathes, Heinz Ruffner & Ursula Graf-Hausner. (2014) The use of skin models in drug development. Advanced Drug Delivery Reviews 69-70, pages 81-102.
Crossref
Crossref
Judith Kuntsche, Angela Herre, Alfred Fahr, S?rgio S. Funari & Patrick Garidel. (2013) Comparative SAXS and DSC study on stratum corneum structural organization in an epidermal cell culture model (ROC): Impact of cultivation time. European Journal of Pharmaceutical Sciences 50:5, pages 577-585.
Crossref
Crossref
Franziska D. Fleischli, Stephanie Mathes & Christian Adlhart. (2013) Label free non-invasive imaging of topically applied actives in reconstructed human epidermis by confocal Raman spectroscopy. Vibrational Spectroscopy 68, pages 29-33.
Crossref
Crossref
Julie A. Evans-Johnson, Jonathan A. Garlick, Elizabeth J. Johnson, Xiang-Dong Wang & C.-Y. Oliver Chen. (2013) A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent. Journal of Photochemistry and Photobiology B: Biology 126, pages 17-25.
Crossref
Crossref
Franzisca Marie Bätz, Wiebke Klipper, Hans Christian Korting, Frank Henkler, Robert Landsiedel, Andreas Luch, Uwe von Fritschen, Günther Weindl & Monika Schäfer-Korting. (2013) Esterase activity in excised and reconstructed human skin – Biotransformation of prednicarbate and the model dye fluorescein diacetate. European Journal of Pharmaceutics and Biopharmaceutics 84:2, pages 374-385.
Crossref
Crossref
Laura M. Pot, Simone M. Scheitza, Pieter‐Jan Coenraads & Brunhilde Blömeke. (2013)
Penetration and haptenation of
p
‐phenylenediamine
. Contact Dermatitis 68:4, pages 193-207.
Crossref
Crossref
Sarah Heilmann, Sarah Küchler, Christian Wischke, Andreas Lendlein, Christoph Stein & Monika Schäfer-Korting. (2013) A thermosensitive morphine-containing hydrogel for the treatment of large-scale skin wounds. International Journal of Pharmaceutics 444:1-2, pages 96-102.
Crossref
Crossref
Matthias Hahne, Michaela Zorn-Kruppa, Gustavo Guzman, Johanna M. Brandner, Eleonore Haltner-Ukomado, Hermann Wätzig & Stephan Reichl. (2012) Prevalidation of a Human Cornea Construct as an Alternative to Animal Corneas for In Vitro Drug Absorption Studies. Journal of Pharmaceutical Sciences 101:8, pages 2976-2988.
Crossref
Crossref
Michel Bouvier d’Yvoire, Susanne Bremer, Silvia Casati, Mara Ceridono, Sandra Coecke, Raffaella Corvi, Chantra Eskes, Laura Gribaldo, Claudius Griesinger, Holger Knaut, Jens P. Linge, Annett Roi & Valérie Zuang. 2012. New Technologies for Toxicity Testing. New Technologies for Toxicity Testing
154
180
.