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Lactoferrin delivery systems: approaches for its more effective use

Pages 1469-1479 | Published online: 06 Sep 2011

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Yun-shan Wei, Kun Feng, Shu-fang Li, Teng-gen Hu, Robert J. Linhardt, Min-hua Zong & Hong Wu. (2022) Oral fate and stabilization technologies of lactoferrin: a systematic review. Critical Reviews in Food Science and Nutrition 62:23, pages 6341-6358.
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Articles from other publishers (30)

Seulbi Kim, Sin Young Hong, Haejin Jeong, Jieun Lee, Kyeongran Park, Hyejin Joo, Seonki Hong, Byoung Sik Kim & Ji Hun Park. (2024) Lactoferrin-polyphenol composite nanocoating with enhanced chemical stability and cell-compatibility. Progress in Organic Coatings 187, pages 108099.
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Farzaneh Hedyeloo, Fatemeh Moradian & Mehran Rostami. (2023) Nanoencapsulation of oral‐pharmaceutical lactoferrin using chitosan and the evaluation of stability against trypsin and pepsin and its antibacterial effect. Micro & Nano Letters 18:9-12.
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Ray Ong, Jillian Cornish & Jingyuan Wen. (2022) Nanoparticular and other carriers to deliver lactoferrin for antimicrobial, antibiofilm and bone-regenerating effects: a review. BioMetals 36:3, pages 709-727.
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Stefania Mottola, Gianluca Viscusi, Giovanna Iannone, Raffaella Belvedere, Antonello Petrella, Iolanda De Marco & Giuliana Gorrasi. (2023) Supercritical Impregnation of Mesoglycan and Lactoferrin on Polyurethane Electrospun Fibers for Wound Healing Applications. International Journal of Molecular Sciences 24:11, pages 9269.
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P. Habibi, F.T. Yazdi, S.A. Mortazavi & M.M. Farajollahi. (2022) Effects of free and nano-encapsulated bovine lactoferrin on the viability and acid production by Streptococcus mutans biofilms. Letters in Applied Microbiology 75:3, pages 689-698.
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Ning Liu, Gang Feng, Xiaoying Zhang, Qingjuan Hu, Shiqiang Sun, Jiaqi Sun, Yanan Sun, Ran Wang, Yan Zhang, Pengjie Wang & Yixuan Li. (2021) The Functional Role of Lactoferrin in Intestine Mucosal Immune System and Inflammatory Bowel Disease. Frontiers in Nutrition 8.
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Friedrich Bialas, Daniela Reichinger & Christian F.W. Becker. (2021) Biomimetic and biopolymer-based enzyme encapsulation. Enzyme and Microbial Technology 150, pages 109864.
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Yu-Qi Li & Chuang Guo. (2021) A Review on Lactoferrin and Central Nervous System Diseases. Cells 10:7, pages 1810.
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Artem A. Antoshin, Anastasia I. Shpichka, Guilin Huang, Kuo Chen, Pengwei Lu, Andrey A. Svistunov, Alexey V. Lychagin, Marina M. Lipina, Mikhail Y. Sinelnikov, Igor V. Reshetov & Peter S. Timashev. (2021) Lactoferrin as a regenerative agent: The old-new panacea?. Pharmacological Research 167, pages 105564.
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P. Wen, W. Zhang, P. Wang, Y. Zhang, W. Zhang, Y. Zhao & H. Guo. (2021) Osteogenic effects of the peptide fraction derived from pepsin-hydrolyzed bovine lactoferrin. Journal of Dairy Science 104:4, pages 3853-3862.
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Esmail M. El-Fakharany. (2020) Nanoformulation of lactoferrin potentiates its activity and enhances novel biotechnological applications. International Journal of Biological Macromolecules 165, pages 970-984.
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Minje Jo, Kyung-Min Park, Jun-Young Park, Hyunjong Yu, Seung Jun Choi & Pahn-Shick Chang. (2020) Microfluidic assembly of mono-dispersed liposome and its surface modification for enhancing the colloidal stability. Colloids and Surfaces A: Physicochemical and Engineering Aspects 586, pages 124202.
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Daniela Vergara & Carolina Shene. (2019) Encapsulation of lactoferrin into rapeseed phospholipids based liposomes: Optimization and physicochemical characterization. Journal of Food Engineering 262, pages 29-38.
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Przemysław Gajda-Morszewski, Klaudyna Śpiewak-Wojtyła, Maria Oszajca & Małgorzata Brindell. (2019) Strategies for Oral Delivery of Metal-Saturated Lactoferrin. Current Protein & Peptide Science 20:11, pages 1046-1051.
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Eunhye Yang, Hyunjong Yu, Jun-Young Park, Kyung-Min Park & Pahn-Shick Chang. (2018) Microfluidic Preparation of Liposomes Using Ethyl Acetate/ n -Hexane Solvents as an Alternative to Chloroform . Journal of Chemistry 2018, pages 1-6.
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Fuguo Liu, Shuhan Zhang, Junyi Li, David Julian McClements & Xuebo Liu. (2018) Recent development of lactoferrin-based vehicles for the delivery of bioactive compounds: Complexes, emulsions, and nanoparticles. Trends in Food Science & Technology 79, pages 67-77.
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Guilherme de Figueiredo Furtado, Karen Cristina Guedes Silva, Cristiane Conte Paim de Andrade & Rosiane Lopes Cunha. (2018) In vitro digestibility of heteroaggregated droplets coated with sodium caseinate and lactoferrin. Journal of Food Engineering 229, pages 86-92.
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Edwin E. Martínez Leo, Armando M. Martín Ortega & Maira R. Segura Campos. 2018. Therapeutic, Probiotic, and Unconventional Foods. Therapeutic, Probiotic, and Unconventional Foods 157 166 .
Hooi Hong Lau, Regan Murney, Nikolai L. Yakovlev, Marina V. Novoselova, Su Hui Lim, Nicole Roy, Harjinder Singh, Gleb B. Sukhorukov, Brendan Haigh & Maxim V. Kiryukhin. (2017) Protein-tannic acid multilayer films: A multifunctional material for microencapsulation of food-derived bioactives. Journal of Colloid and Interface Science 505, pages 332-340.
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Shuang Liu, Shi-meng Zhang, Rui-jun Ju, Yao Xiao, Xin Wang, Xiao-li Song, Li-yan Gu, Lan Cheng, Xue-tao Li & Gui-rong Chen. (2017) Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma. European Journal of Pharmaceutical Sciences 106, pages 185-197.
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Ece Kilic, Marina V. Novoselova, Su Hui Lim, Nikolay A. Pyataev, Sergey I. Pinyaev, Oleg A. Kulikov, Olga A. Sindeeva, Oksana A. Mayorova, Regan Murney, Maria N. Antipina, Brendan Haigh, Gleb B. Sukhorukov & Maxim V. Kiryukhin. (2017) Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules. Scientific Reports 7:1.
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Patricia Martorell, Silvia Llopis, Nuria Gonzalez, Daniel Ramón, Gabriel Serrano, Ana Torrens, Juan M. Serrano, Maria Navarro & Salvador Genovés. (2017) A nutritional supplement containing lactoferrin stimulates the immune system, extends lifespan, and reduces amyloid β peptide toxicity in Caenorhabditis elegans . Food Science & Nutrition 5:2, pages 255-265.
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Francesco Giansanti, Gloria Panella, Loris Leboffe & Giovanni Antonini. (2016) Lactoferrin from Milk: Nutraceutical and Pharmacological Properties. Pharmaceuticals 9:4, pages 61.
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Huma Bokkhim, Nidhi Bansal, Lisbeth Grøndahl & Bhesh Bhandari. (2016) Characterization of alginate–lactoferrin beads prepared by extrusion gelation method. Food Hydrocolloids 53, pages 270-276.
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Ching-Wei Tsai, Wei-Wen Hu, Chih-I Liu, Ruoh-Chyu Ruaan, Bing-Chang Tsai, Shiow-Lian Catherine Jin, Yung Chang & Wen-Yih Chen. (2015) The consideration of indolicidin modification to balance its hemocompatibility and delivery efficiency. International Journal of Pharmaceutics 494:1, pages 498-505.
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Huma Bokkhim, Nidhi Bansal, Lisbeth Grøndahl & Bhesh Bhandari. (2015) Interactions between different forms of bovine lactoferrin and sodium alginate affect the properties of their mixtures. Food Hydrocolloids 48, pages 38-46.
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Jagat Kanwar, Kislay Roy, Yogesh Patel, Shu-Feng Zhou, Manju Singh, Deependra Singh, Muhammad Nasir, Rakesh Sehgal, Alka Sehgal, Ram Singh, Sanjay Garg & Rupinder Kanwar. (2015) Multifunctional Iron Bound Lactoferrin and Nanomedicinal Approaches to Enhance Its Bioactive Functions. Molecules 20:6, pages 9703-9731.
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Sung Eun Kim, Young-Pil Yun, Jae Yong Lee, Kyeongsoon Park & Dong Hun Suh. (2014) Osteoblast activity of MG-63 cells is enhanced by growth on a lactoferrin-immobilized titanium substrate. Colloids and Surfaces B: Biointerfaces 123, pages 191-198.
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Irene Pereira de Sousa & Andreas Bernkop-Schnürch. (2014) Pre-systemic metabolism of orally administered drugs and strategies to overcome it. Journal of Controlled Release 192, pages 301-309.
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Jennifer McBride, Lia R Walker, Philippe A Grange, Nicolas Dupin & Shaw M Akula. (2013) Molecular biology of lactoferrin and its role in modulating immunity and viral pathogenesis. Future Virology 8:3, pages 289-299.
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