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Solid dispersions, Part I: recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

Pages 1501-1519 | Published online: 16 Sep 2011

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Maryam Maghsoodi, Saeideh Mollaie Astemal, Ali Nokhodchi, Hossein Kiaie & Fatemeh Talebi. (2023) The effect of anionic Eudragit polymers on drug supersaturation and in vitro permeation improvement. Drug Development and Industrial Pharmacy 49:4, pages 295-304.
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Nian-Qiu Shi, Hong-Wei Lai, Yong Zhang, Bo Feng, Xiao Xiao, Hong-Mei Zhang, Zheng-Qiang Li & Xian-Rong Qi. (2018) On the inherent properties of Soluplus and its application in ibuprofen solid dispersions generated by microwave-quench cooling technology. Pharmaceutical Development and Technology 23:6, pages 573-586.
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Hongzhi Qiao, Lihua Chen, Tianqi Rui, Jingxian Wang, Ting Chen, Tingming Fu, Junsong Li & Liuqing Di. (2017) Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate. International Journal of Nanomedicine 12, pages 1033-1046.
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Djordje P. Medarević, Peter Kleinebudde, Jelena Djuriš, Zorica Djurić & Svetlana Ibrić. (2016) Combined application of mixture experimental design and artificial neural networks in the solid dispersion development. Drug Development and Industrial Pharmacy 42:3, pages 389-402.
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Anastasia W. Irwan, Jacqueline E. Berania & Xueming Liu. (2016) A comparative study on the effects of amphiphilic and hydrophilic polymers on the release profiles of a poorly water-soluble drug. Pharmaceutical Development and Technology 21:2, pages 231-238.
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Jiannan Lu, Sejal Shah, Seongbong Jo, Soumyajit Majumdar, Andreas Gryczke, Karl Kolter, Nigel Langley & Michael A. Repka. (2015) Investigation of phase diagrams and physical stability of drug–polymer solid dispersions. Pharmaceutical Development and Technology 20:1, pages 105-117.
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P. A. Sonar, A. L. Behera, S. K. Banerjee, D. D. Gaikwad & S. L. Harer. (2015) Preparation and characterization of Simvastatin solid dispersion using skimmed milk. Drug Development and Industrial Pharmacy 41:1, pages 22-27.
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Zhe-Peng Liu, Lei Cui, Deng-Guang Yu, Zhuan-Xia Zhao & Lan Chen. (2014) Electrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head. International Journal of Nanomedicine 9, pages 1967-1977.
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Kerstin J Frank, Ulrich Westedt, Karin M Rosenblatt, Peter Hölig, Jörg Rosenberg, Markus Mägerlein, Gert Fricker & Martin Brandl. (2012) The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility. International Journal of Nanomedicine 7, pages 5757-5768.
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Mohd Aftab Alam, Raisuddin Ali, Fahad Ibrahim Al-Jenoobi & Abdullah M Al-Mohizea. (2012) Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates. Expert Opinion on Drug Delivery 9:11, pages 1419-1440.
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Deng-Guang Yu, Li-Min Zhu, Christopher J Branford-White, Jun-He Yang, Xia Wang, Ying Li & Wei Qian. (2011) Solid dispersions in the form of electrospun core-sheath nanofibers. International Journal of Nanomedicine 6, pages 3271-3280.
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