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Inhaled colistin for lower respiratory tract infections

, MD PhD & , MD PhD
Pages 333-342 | Published online: 14 Feb 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

David de la Rosa-Carrillo, Guillermo Suárez-Cuartín, Rafael Golpe, Luis Máiz Carro & Miguel Angel Martinez-Garcia. (2022) Inhaled Colistimethate Sodium in the Management of Patients with Bronchiectasis Infected by Pseudomonas aeruginosa: A Narrative Review of Current Evidence. Infection and Drug Resistance 15, pages 7271-7292.
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Sujit Kumar Debnath, Rohit Srivastava, Monalisha Debnath & Abdelwahab Omri. (2021) Status of inhalable antimicrobial agents for lung infection: progress and prospects. Expert Review of Respiratory Medicine 15:10, pages 1251-1270.
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Matthew P Schreiber & Andrew F Shorr. (2017) Challenges and opportunities in the treatment of ventilator-associated pneumonia. Expert Review of Anti-infective Therapy 15:1, pages 23-32.
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Foroud Shahbazi & Simin Dashti-Khavidaki. (2015) Colistin: efficacy and safety in different populations. Expert Review of Clinical Pharmacology 8:4, pages 423-448.
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Argyris S Michalopoulos. (2012) Aerosolized antibiotics: the past, present and future, with a special emphasis on inhaled colistin. Expert Opinion on Drug Delivery 9:5, pages 493-495.
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Articles from other publishers (29)

Rupeng Shi, Yuanyuan Fu, Yujing Gan, Danying Wu, Suming Zhou & Min Huang. (2023) Use of polymyxin B with different administration methods in the critically ill patients with ventilation associated pneumonia: a single-center experience. Frontiers in Pharmacology 14.
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Sujit Kumar Debnath, Monalisha Debnath & Rohit Srivastava. (2022) Opportunistic etiological agents causing lung infections: emerging need to transform lung-targeted delivery. Heliyon 8:12, pages e12620.
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Vaibhav Pathak, Heejun Park, Dmitry Zemlyanov, Sonal V. Bhujbal, Maizbha Uddin Ahmed, Mohammad A. K. Azad, Jian Li & Qi Tony Zhou. (2022) Improved Aerosolization Stability of Inhalable Tobramycin Powder Formulation by Co-Spray Drying with Colistin. Pharmaceutical Research 39:11, pages 2781-2799.
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Adriana Mihaela Dan, Diana Iulia Vasilescu, Andreea Gogoncea & Monica Mihaela Cîrstoiu. (2022) Aerosolized antibiotics – can they save us?. Obstetrica şi Ginecologia 3:70, pages 130.
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Maizbha U. Ahmed, Mohammad A. K. Azad, Mengyao Li, Darren J. Creek, Meiling Han, Fanfan Zhou, Kim Chan, Qi Tony Zhou, Tony Velkov & Jian Li. (2021) Polymyxin-Induced Metabolic Perturbations in Human Lung Epithelial Cells. Antimicrobial Agents and Chemotherapy 65:9.
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Li Ding, Jieliang Wang, Shihao Cai, Hugh Smyth & Zhengrong Cui. (2021) Pulmonary biofilm-based chronic infections and inhaled treatment strategies. International Journal of Pharmaceutics 604, pages 120768.
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Mohamad A. K. Azad, Shuo Zhang, Jiayao Li, Yeonuk Kim, Heidi H. Yu, Alex J. Fulcher, Daryl L. Howard, Martin D. de Jonge, Simon A. James, Kade D. Roberts, Tony Velkov, Jing Fu, Qi Tony Zhou & Jian Li. (2021) Synchrotron-Based X-Ray Fluorescence Microscopy Reveals Accumulation of Polymyxins in Single Human Alveolar Epithelial Cells. Antimicrobial Agents and Chemotherapy 65:5.
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Sue C. Nang, Mohammad A. K. Azad, Tony Velkov, Qi (Tony) Zhou & Jian Li. (2021) Rescuing the Last-Line Polymyxins: Achievements and Challenges. Pharmacological Reviews 73:2, pages 679-728.
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Nivedita Shetty, Yiwen Zhang, Heejun Park, Dmitry Zemlyanov, Dishan Shah, Athena He, Patricia Ahn, Tarun Tejasvi Mutukuri, Hak-Kim Chan & Qi Zhou. (2020) Surface Composition and Aerosolization Stability of an Inhalable Combinational Powder Formulation Spray Dried Using a Three-Fluid Nozzle. Pharmaceutical Research 37:11.
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Francesca Ghirga, Roberta Stefanelli, Luca Cavinato, Alessandra Lo Sciuto, Silvia Corradi, Deborah Quaglio, Andrea Calcaterra, Bruno Casciaro, Maria Rosa Loffredo, Floriana Cappiello, Patrizia Morelli, Alberto Antonelli, Gian Maria Rossolini, Marialuisa Mangoni, Carmine Mancone, Bruno Botta, Mattia Mori, Fiorentina Ascenzioni & Francesco Imperi. (2020) A novel colistin adjuvant identified by virtual screening for ArnT inhibitors. Journal of Antimicrobial Chemotherapy 75:9, pages 2564-2572.
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Da-Wei Wu, Song-Wei Wang, Ya-Fan Chang & Jui-Hsiu Tsai. (2020) Effective pharmacotherapy for lung abscess in a patient with alcoholism. Respiratory Medicine Case Reports 30, pages 101061.
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Maizbha U Ahmed, Tony Velkov, Qi Tony Zhou, Alex J Fulcher, Judy Callaghan, Fanfan Zhou, Kim Chan, Mohammad A K Azad & Jian Li. (2018) Intracellular localization of polymyxins in human alveolar epithelial cells. Journal of Antimicrobial Chemotherapy.
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Miguel Angel Martinez-García. (2018) Pseudomonas aeruginosa infection and exacerbations in bronchiectasis: more questions than answers . European Respiratory Journal 51:2, pages 1702497.
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Omid Moradi Moghadam, Reza Ghanbarpour, Mohammad Niakan, Mahshid Talebi Taher, Valiollah Hassani, Alireza Dadashi & Ebad Shiri. (2018) Assessment of Renal Damage in Patients with Multi-Drug Resistant Strains of Pneumonia Treated with Colistin. Trauma Monthly 23:1.
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Nicolas Grégoire, Vincent Aranzana-Climent, Sophie Magréault, Sandrine Marchand & William Couet. (2017) Clinical Pharmacokinetics and Pharmacodynamics of Colistin. Clinical Pharmacokinetics 56:12, pages 1441-1460.
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Ranjani Somayaji, James A. Elliott, Reneeka Persaud, Morgan Lim, Laurie Goodman & R. Gary Sibbald. (2017) The impact of team based interprofessional comprehensive assessments on the diagnosis and management of diabetic foot ulcers: A retrospective cohort study. PLOS ONE 12:9, pages e0185251.
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Maizbha U. Ahmed, Tony Velkov, Yu-Wei Lin, Bo Yun, Cameron J. Nowell, Fanfan Zhou, Qi Tony Zhou, Kim Chan, Mohammad A. K. Azad & Jian Li. (2017) Potential Toxicity of Polymyxins in Human Lung Epithelial Cells. Antimicrobial Agents and Chemotherapy 61:6.
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Sami Abdellatif, Ahlem Trifi, Foued Daly, Khaoula Mahjoub, Rochdi Nasri & Salah Ben Lakhal. (2016) Efficacy and toxicity of aerosolised colistin in ventilator-associated pneumonia: a prospective, randomised trial. Annals of Intensive Care 6:1.
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Jaideep S. Talwalkar & Thomas S. Murray. (2016) The Approach to Pseudomonas aeruginosa in Cystic Fibrosis. Clinics in Chest Medicine 37:1, pages 69-81.
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Teresa Jong, Jian Li, David A.V. Morton, Qi (Tony) Zhou & Ian Larson. (2016) Investigation of the Changes in Aerosolization Behavior Between the Jet-Milled and Spray-Dried Colistin Powders Through Surface Energy Characterization. Journal of Pharmaceutical Sciences 105:3, pages 1156-1163.
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Qi (Tony) Zhou, Si-Ping Sun, John Gar Yan ChanPing Wang, Nicolas Barraud, Scott A. Rice, Jiping Wang, Jian Li & Hak-Kim Chan. (2014) Novel Inhaled Combination Powder Containing Amorphous Colistin and Crystalline Rifapentine with Enhanced Antimicrobial Activities against Planktonic Cells and Biofilm of Pseudomonas aeruginosa for Respiratory Infections . Molecular Pharmaceutics 12:8, pages 2594-2603.
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Meltem Polat, Soner Sertan Kara, Anıl Tapısız, Hasan Tezer, Gökhan Kalkan & Anıl Dolgun. (2015) Treatment of Ventilator-Associated Pneumonia Using Intravenous Colistin Alone or in Combination with Inhaled Colistin in Critically Ill Children. Pediatric Drugs 17:4, pages 323-330.
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Qi (Tony) Zhou, Sharon Shui Yee Leung, Patricia Tang, Thaigarajan Parumasivam, Zhi Hui Loh & Hak-Kim Chan. (2015) Inhaled formulations and pulmonary drug delivery systems for respiratory infections. Advanced Drug Delivery Reviews 85, pages 83-99.
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Mohan Gurjar. (2015) Colistin for lung infection: an update. Journal of Intensive Care 3:1, pages 3.
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Qi Zhou, Thomas Gengenbach, John A. Denman, Heidi H. Yu, Jian Li & Hak Kim Chan. (2013) Synergistic Antibiotic Combination Powders of Colistin and Rifampicin Provide High Aerosolization Efficiency and Moisture Protection. The AAPS Journal 16:1, pages 37-47.
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Shalini W. S. Yapa, Jian Li, Christopher J. H. Porter, Roger L. Nation, Kashyap Patel & Michelle P. McIntosh. (2013) Population Pharmacokinetics of Colistin Methanesulfonate in Rats: Achieving Sustained Lung Concentrations of Colistin for Targeting Respiratory Infections. Antimicrobial Agents and Chemotherapy 57:10, pages 5087-5095.
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Qi (Tony) Zhou, David A.V. Morton, Heidi H. Yu, Jovan Jacob, Jiping Wang, Jian Li & Hak Kim Chan. (2013) Colistin Powders with High Aerosolisation Efficiency for Respiratory Infection: Preparation and In Vitro Evaluation. Journal of Pharmaceutical Sciences 102:10, pages 3736-3747.
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David CipollaHak-Kim Chan. (2013) Inhaled antibiotics to treat lung infection. Pharmaceutical Patent Analyst 2:5, pages 647-663.
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Sandrine GiraudLoïc Favennec, Marie-Elisabeth Bougnoux & Jean-Philippe Bouchara. (2013) Rasamsonia argillacea species complex: taxonomy, pathogenesis and clinical relevance . Future Microbiology 8:8, pages 967-978.
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