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Original Research

Myo-inositol in a new pharmaceutical form: a step forward to a broader clinical use

, PhD, , PhD, , MD &
Pages 267-271 | Published online: 20 Feb 2012

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Read on this site (4)

Mariano Bizzarri, Patrizia Logoteta, Giovanni Monastra & Antonio Simone Laganà. (2022) An innovative approach to polycystic ovary syndrome. Journal of Obstetrics and Gynaecology 42:4, pages 546-556.
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Mariano Bizzarri, Andrea Fuso, Simona Dinicola, Alessandra Cucina & Arturo Bevilacqua. (2016) Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease. Expert Opinion on Drug Metabolism & Toxicology 12:10, pages 1181-1196.
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John E. Nestler & Vittorio Unfer. (2015) Reflections on inositol(s) for PCOS therapy: steps toward success. Gynecological Endocrinology 31:7, pages 501-505.
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Salvatore Benvenga. (2012) (Soft) capsules of wisdom: preventing myo-inositol malabsorption caused by coffee. Expert Opinion on Drug Delivery 9:10, pages 1177-1179.
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Articles from other publishers (22)

Sayeree Joardar, Prangan Duarah & Mihir Kumar Purkait. (2023) Recent advances in myo-inositol recovery and purification from agricultural sources as potential dietary supplements: A review. Sustainable Chemistry and Pharmacy 36, pages 101331.
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Ariel Beresniak, Michele Russo, Gianpiero Forte, Antonio Simone Laganà, Mario Montanino Oliva, Cesare Aragona, Vito Chiantera & Vittorio Unfer. (2023) A Markov-model simulation of IVF programs for PCOS patients indicates that coupling myo-Inositol with rFSH is cost-effective for the Italian Health System. Scientific Reports 13:1.
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Irene Christopoulou, Eirini Kostopoulou, Konstantina Matzarapi, Styliani A. Chasapi, Georgios A. Spyroulias & Anastasia Varvarigou. (2023) Identification of Novel Biomarkers in Late Preterm Neonates with Respiratory Distress Syndrome (RDS) Using Urinary Metabolomic Analysis. Metabolites 13:5, pages 644.
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Simona Dinicola, Vittorio Unfer, Fabio Facchinetti, Christophe O. Soulage, Nicholas D. Greene, Mariano Bizzarri, Antonio Simone Laganà, Shiao-Yng Chan, Arturo Bevilacqua, Lali Pkhaladze, Salvatore Benvenga, Annarita Stringaro, Daniele Barbaro, Marialuisa Appetecchia, Cesare Aragona, Maria Salomè Bezerra Espinola, Tonino Cantelmi, Pietro Cavalli, Tony T. Chiu, Andrew J. Copp, Rosario D’Anna, Didier Dewailly, Cherubino Di Lorenzo, Evanthia Diamanti-Kandarakis, Imelda Hernández Marín, Moshe Hod, Zdravko Kamenov, Eleni Kandaraki, Giovanni Monastra, Mario Montanino Oliva, John E. Nestler, Maurizio Nordio, Ali C. Ozay, Olga Papalou, Giuseppina Porcaro, Nikos Prapas, Scott Roseff, Monica Vazquez-Levin, Ivana Vucenik & Artur Wdowiak. (2021) Inositols: From Established Knowledge to Novel Approaches. International Journal of Molecular Sciences 22:19, pages 10575.
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Maria Pompea Antonia Baldassarre, Pamela Di Tomo, Giorgia Centorame, Assunta Pandolfi, Natalia Di Pietro, Agostino Consoli & Gloria Formoso. (2021) Myoinositol Reduces Inflammation and Oxidative Stress in Human Endothelial Cells Exposed In Vivo to Chronic Hyperglycemia. Nutrients 13:7, pages 2210.
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Luc P. Brion, Dale L. Phelps, Robert M. Ward, Tracy L. Nolen, N. Mikko K. Hallman, Abhik Das, Daniel J. Zaccaro, M. Bethany Ball, Kristi L. Watterberg, Ivan D. FrantzIIIIII, C. Michael Cotten, Brenda B. Poindexter, William Oh, Ralph A. Lugo, Krisa P. Van Meurs, T. Michael O’Shea, Kristin M. Zaterka-Baxter, Rosemary D. Higgins, Alan H. Jobe, Michael S. Caplan, Abbot R. Laptook, Angelita M. Hensman, Ronald N. Goldberg, Kathy J. Auten, Stephanie Wilson Archer, James A. Lemons, Dianne E. Herron, Leslie Dawn Wilson, W. Kenneth Poole, Jeanette O’Donnell Auman, Betty K. Hastings, Norbert T. Kadima, James W. PickettIIII, Lisa A. Wrage, Patricia Chess, Linda J. Reubens, Erica Burnell, Mary Rowan, Cassandra A. Horihan, Nancy J. Peters, Richard A. Ehrenkranz, Patricia Gettner, Monica Konstantino, Joann Poulsen & Janet Taft. (2020) Blood myo-inositol concentrations in preterm and term infants. Journal of Perinatology 41:2, pages 247-254.
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Luciana N. Moreira, Clarissa Feltrin, José E. Gonçalves, Whocely V. de Castro, Cláudia M.O. Simões, Rodrigo M. de Pádua, Steyner F. Cortes & Fernão C. Braga. (2020) Determination of l-(+)-bornesitol, the hypotensive constituent of Hancornia speciosa, in rat plasma by LC-MS/MS and its application on a pharmacokinetic study. Biomedicine & Pharmacotherapy 132, pages 110900.
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John S. Markowitz, Patrick C. Gurley & Bill J. Gurley. (2020) Medical Foods—A Closer Look at the Menu: A Brief Review and Commentary. Clinical Therapeutics 42:7, pages 1416-1423.
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Tingting Wei, Qi Shu, Jie Ning, Shuaijie Wang, Chen Li, Liangcai Zhao, Hong Zheng & Hongchang Gao. (2020) The Protective Effect of Basic Fibroblast Growth Factor on Diabetic Nephropathy Through Remodeling Metabolic Phenotype and Suppressing Oxidative Stress in Mice. Frontiers in Pharmacology 11.
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Heidy Cabrera-Cruz, Lorena Oróstica, Francisca Plaza-Parrochia, Ignacio Torres-Pinto, Carmen Romero & Margarita Vega. (2020) The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS environment. American Journal of Physiology-Endocrinology and Metabolism 318:2, pages E237-E248.
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І. А. Жабченко & О. Р. Сюдмак. (2019) Problems of delayed birth: the features of fertility in older reproductive age women and their correction methods. Reproductive Endocrinology 0:49, pages 43-49.
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Anna Wojciechowska, Adam Osowski, Marcin Jóźwik, Ryszard Górecki, Andrzej Rynkiewicz & Joanna Wojtkiewicz. (2019) Inositols’ Importance in the Improvement of the Endocrine–Metabolic Profile in PCOS. International Journal of Molecular Sciences 20:22, pages 5787.
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Gloria Formoso, Maria P.A. Baldassarre, Federica Ginestra, Maria Assunta Carlucci, Ines Bucci & Agostino Consoli. (2019) Inositol and antioxidant supplementation: Safety and efficacy in pregnancy. Diabetes/Metabolism Research and Reviews 35:5.
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Simona Dinicola, Mirko Minini, Vittorio Unfer, Roberto Verna, Alessandra Cucina & Mariano Bizzarri. (2017) Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders. International Journal of Molecular Sciences 18:10, pages 2187.
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P.M. Rendle, F. Kassibawi, K.A. Johnston, J.B. Hart, S.A. Cameron, A. Falshaw, G.F. Painter & K.M. Loomes. (2016) Synthesis and biological activities of d - chiro -inositol analogues with insulin-like actions. European Journal of Medicinal Chemistry 122, pages 442-451.
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Vittorio Unfer, John E. Nestler, Zdravko A. Kamenov, Nikos Prapas & Fabio Facchinetti. (2016) Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials. International Journal of Endocrinology 2016, pages 1-12.
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Fabio Facchinetti, Giulia Dante & Isabella Neri. 2016. Frontiers in Gynecological Endocrinology. Frontiers in Gynecological Endocrinology 103 109 .
Tingting Wei, Liangcai Zhao, Jianmin Jia, Huanhuan Xia, Yao Du, Qiuting Lin, Xiaodong Lin, Xinjian Ye, Zhihan Yan & Hongchang Gao. (2015) Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice. Scientific Reports 5:1.
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Vittorio Unfer, Gianfranco Carlomagno, Enrico Papaleo, Simona Vailati, Massimo Candiani & Jean-Patrice Baillargeon. (2014) Hyperinsulinemia Alters Myoinositol to d-chiroinositol Ratio in the Follicular Fluid of Patients With PCOS. Reproductive Sciences 21:7, pages 854-858.
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Yoshifumi Murata, Takashi Isobe, Kyoko Kofuji, Masafumi Mizutani & Ryosei Kamaguchi. (2012) Development of Oral Dissolving Gelatin Beads Containing Allopurinol for the Prevention and Treatment of Mucositis. Pharmacology & Pharmacy 03:03, pages 295-299.
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