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Original Research

Solid lipid nanoparticles-loaded topical gel containing combination drugs: an approach to offset psoriasis

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Yulin Hua, Tiantian Chang, Kun Jiang, Jinhong Wang, Xiaodong Cui, Min Cheng, Fang Yan, Bo Song & Yuzhen Wang. (2022) ROS-sensitive calcipotriol nano-micelles prepared by methoxypolyethylene glycol (mPEG) – modified polymer for the treatment of psoriasis. Drug Delivery 29:1, pages 1903-1913.
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Heidi M. Abdel-Mageed, Amira E. Abd El Aziz, Saleh A. Mohamed & Nermeen Z. AbuelEzz. (2022) The tiny big world of solid lipid nanoparticles and nanostructured lipid carriers: an updated review. Journal of Microencapsulation 39:1, pages 72-94.
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Oly Katari & Sanyog Jain. (2021) Solid lipid nanoparticles and nanostructured lipid carrier-based nanotherapeutics for the treatment of psoriasis. Expert Opinion on Drug Delivery 18:12, pages 1857-1872.
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Ghada M. El-Zaafarany & Maha Nasr. (2021) Insightful exploring of advanced nanocarriers for the topical/transdermal treatment of skin diseases. Pharmaceutical Development and Technology 26:10, pages 1136-1157.
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Yuzhen Wang, Hong Li, Fakun Dong, Fang Yan, Min Cheng, Wanzhong Li, Qi Chang, Tianzi Song, Aoying Liu & Bo Song. (2020) Therapeutic Effect of Calcipotriol Pickering Nanoemulsions Prepared by Exopolysaccharides Produced by Bacillus halotolerans FYS Strain on Psoriasis. International Journal of Nanomedicine 15, pages 10371-10384.
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Padmini Ravikumar, Mahesh Katariya, Sushil Patil, Pratima Tatke & Raviraj Pillai. (2019) Skin delivery of resveratrol encapsulated lipidic formulation for melanoma chemoprevention. Journal of Microencapsulation 36:6, pages 535-551.
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Mahfoozur Rahman, Shareefa Abdullah Al-Ghamdi, Khalid S Alharbi, Sarwar Beg, Kalicharan Sharma, Firoz Anwar, Fahad A Al-Abbasi & Vikas Kumar. (2019) Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma. Drug Delivery 26:1, pages 782-793.
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Sara Salatin, Mitra Alami-Milani, Rosita Daneshgar & Mitra Jelvehgari. (2018) Box–Behnken experimental design for preparation and optimization of the intranasal gels of selegiline hydrochloride. Drug Development and Industrial Pharmacy 44:10, pages 1613-1621.
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Kritika Nayak, Sameer S. Katiyar, Varun Kushwah & Sanyog Jain. (2018) Coenzyme Q10 and retinaldehyde co-loaded nanostructured lipid carriers for efficacy evaluation in wrinkles. Journal of Drug Targeting 26:4, pages 333-344.
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Rakesh Kumar & Vivek Ranjan Sinha. (2016) Solid lipid nanoparticle: an efficient carrier for improved ocular permeation of voriconazole. Drug Development and Industrial Pharmacy 42:12, pages 1956-1967.
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Articles from other publishers (73)

Devika Tripathi, Mansi Srivastava, Krislay Rathour, Awani Kumar Rai, Pranay Wal, Jagannath Sahoo, Ritesh Kumar Tiwari & Prashant Pandey. (2023) A Promising Approach of Dermal Targeting of Antipsoriatic Drugs via Engineered Nanocarriers Drug Delivery Systems for Tackling Psoriasis. Drug Metabolism and Bioanalysis Letters 16:2, pages 89-104.
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Meraj Alam, Md. Rizwanullah, Showkat R. Mir & Saima Amin. (2023) Statistically Optimized Tacrolimus and Thymoquinone Co-Loaded Nanostructured Lipid Carriers Gel for Improved Topical Treatment of Psoriasis. Gels 9:7, pages 515.
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Vamshi Krishna Rapalli, Yashika Tomar, Swati Sharma, Aniruddha Roy & Gautam Singhvi. (2023) Apremilast loaded lyotropic liquid crystalline nanoparticles embedded hydrogel for improved permeation and skin retention: An effective approach for psoriasis treatment. Biomedicine & Pharmacotherapy 162, pages 114634.
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Meraj Alam, Md. Rizwanullah, Showkat Rasool Mir & Saima Amin. (2023) Promising prospects of lipid-based topical nanocarriers for the treatment of psoriasis. OpenNano 10, pages 100123.
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Manishi Mahajan, Manjot Kaur, Shubham Thakur, Amrinder Singh, Navid Reza Shahtaghi, Riya Shivgotra, Nitish Bhardwaj, Shagun Saini & Subheet Kumar Jain. (2022) Solid Lipid Nanoparticles as Carrier to Increase Local Bioavailability of Acitretin After Topical Administration in Psoriasis Treatment. Journal of Pharmaceutical Innovation 18:1, pages 220-237.
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Janaína Artem Ataide, Julia Cedran Coco, Érica Mendes dos Santos, Viviane Beraldo-Araujo, Jéssica Ribeiro Alves Silva, Karine Cappuccio de Castro, André Moreni Lopes, Nina Filipczak, Satya Siva Kishan Yalamarty, Vladimir P. Torchilin & Priscila Gava Mazzola. (2023) Co-Encapsulation of Drugs for Topical Application—A Review. Molecules 28:3, pages 1449.
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ANILKUMAR J. SHINDE, SHREYASH D. TARLEKAR, RAVINDRA J. JARAG & FIROJ A. TAMBOLI. (2023) ANTIPSORIATIC ACTIVITY OF HYDROGEL CONTAINING NANOSTRUCTURED LIPID CARRIER (NLC) ENTRAPPED WITH TRIAMCINOLONE ACETONIDE. International Journal of Applied Pharmaceutics, pages 308-317.
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Mohammad Zaki Ahmad, Abdul Aleem Mohammed, Mohammed S. Algahtani, Awanish Mishra & Javed Ahmad. (2022) Nanoscale Topical Pharmacotherapy in Management of Psoriasis: Contemporary Research and Scope. Journal of Functional Biomaterials 14:1, pages 19.
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Miao Zhang, Seokgyeong Hong, Xiaoying Sun, Yaqiong Zhou, Ying Luo, Liu Liu, Jiao Wang, Chunxiao Wang, Naixuan Lin & Xin Li. (2022) Exploration of and insights into advanced topical nanocarrier systems for the treatment of psoriasis. Frontiers in Medicine 9.
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Zari Salahuddin, Muhammad Usman Ali Khan & Tasleem Akhtar. (2022) Psoriasis, An Overview of its Pathogenesis and Available Treatment Modalities. Albus Scientia 2022:2, pages 1-5.
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Francesca Selmin, Silvia Franzè, Antonella Casiraghi & Francesco Cilurzo. (2022) Spotlight on Calcipotriol/Betamethasone Fixed-Dose Combination in Topical Formulations: Is There Still Room for Innovation?. Pharmaceutics 14:10, pages 2085.
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Anqi Chen, Yuting Luo, Jie Xu, Xueran Guan, Huacheng He, Xuan Xuan & Jiang Wu. (2022) Latest on biomaterial-based therapies for topical treatment of psoriasis. Journal of Materials Chemistry B 10:37, pages 7397-7417.
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Jyoti Sharma & Ripu Daman. (2022) Molecular Analysis, Pathophysiology, and Drug Delivery Mechanism with Reference to Psoriasis: A Review. Oriental Journal Of Chemistry 38:4, pages 940-947.
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Shaheen Parveen, Musheer Ahmed, Sanjula Baboota & Javed Ali. (2022) An Innovative Approach in Nanotechnology-based Delivery System for the Effective Management of Psoriasis. Current Pharmaceutical Design 28:13, pages 1082-1102.
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Ning Li, Yeping Qin, Dan Dai, Pengyu Wang, Mingfei Shi, Junwei Gao, Jinsheng Yang, Wei Xiao, Ping Song & Ruodan Xu. (2022) Transdermal Delivery of Therapeutic Compounds With Nanotechnological Approaches in Psoriasis. Frontiers in Bioengineering and Biotechnology 9.
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JINAL SHAH, SHOAIB PATEL, SRINIVAS BHAIRY & RAJASHREE HIRLEKAR. (2022) FORMULATION OPTIMIZATION, CHARACTERIZATION AND IN VITRO ANTI-CANCER ACTIVITY OF CURCUMIN LOADED NANOSTRUCTURED LIPID CARRIERS. International Journal of Current Pharmaceutical Research, pages 31-43.
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Dheeraj KatariaAmeeduzzafar ZafarJaved AliKarishma KhatoonSaba KhanSyed Sarim ImamMohd YasirAsgar Ali. (2022) Formulation of Lipid-Based Nanocarriers of Lacidipine for Improvement of Oral Delivery: Box-Behnken Design Optimization, In Vitro , Ex Vivo , and Preclinical Assessment . ASSAY and Drug Development Technologies 20:1, pages 5-21.
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Muhammad Raza Shah, Muhammad Imran & Shafi Ullah. 2022. Nanocarriers for Organ-Specific and Localized Drug Delivery. Nanocarriers for Organ-Specific and Localized Drug Delivery 135 166 .
Prashansha Mullick, Sadhana P Mutalik, Aswathi R Hegde, Abhijeet Pandey, P C Jagadish, Suvarna G Kini, Sanyog Jain & Srinivas Mutalik. (2021) Simultaneous Estimation of Apremilast and Betamethasone Dipropionate in Microsponge-Based Topical Formulation using a Stability Indicating RP-HPLC Method: A Quality-by-Design Approach. Journal of Chromatographic Science 59:10, pages 928-940.
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Mohhammad Ramzan, Gurpreet Kaur, Sonia Trehan, Javed N. Agrewala, Bozena B. Michniak-Kohn, Afzal Hussain, Wael A. Mahdi, Jaspreet Singh Gulati & Indu Pal Kaur. (2021) Mechanistic evaluations of ketoconazole lipidic nanoparticles for improved efficacy, enhanced topical penetration, cellular uptake (L929 and J774A.1), and safety assessment: In vitro and in vivo studies. Journal of Drug Delivery Science and Technology 65, pages 102743.
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Vamshi Krishna Rapalli, Swati Sharma, Aniruddha Roy & Gautam Singhvi. (2021) Design and dermatokinetic evaluation of Apremilast loaded nanostructured lipid carriers embedded gel for topical delivery: A potential approach for improved permeation and prolong skin deposition. Colloids and Surfaces B: Biointerfaces 206, pages 111945.
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Sudeep Sudesh Pukale, Anupama Mittal & Deepak Chitkara. (2021) Topical Application of Vitamin D3-Loaded Hybrid Nanosystem to Offset Imiquimod-Induced Psoriasis. AAPS PharmSciTech 22:7.
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Krishna Yadav, Deependra Singh & Manju Rawat Singh. (2021) Novel archetype in psoriasis management bridging molecular dynamics in exploring novel therapies. European Journal of Pharmacology 907, pages 174254.
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Varunesh Sanjay Tambe, Avni Nautiyal & Sarika Wairkar. (2021) Topical lipid nanocarriers for management of psoriasis-an overview. Journal of Drug Delivery Science and Technology 64, pages 102671.
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Kshitya Shetty & Atul P. Sherje. (2021) Nano intervention in topical delivery of corticosteroid for psoriasis and atopic dermatitis—a systematic review. Journal of Materials Science: Materials in Medicine 32:8.
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Prativa Biswasroy, Deepak Pradhan, Biswakanth Kar, Goutam Ghosh & Goutam Rath. (2021) Recent Advancement in Topical Nanocarriers for the Treatment of Psoriasis. AAPS PharmSciTech 22:5.
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Vamshi Krishna Rapalli, Swati Sharma, Aniruddha Roy, Amit Alexander & Gautam Singhvi. (2021) Solid lipid nanocarriers embedded hydrogel for topical delivery of apremilast: In-vitro, ex-vivo, dermatopharmacokinetic and anti-psoriatic evaluation. Journal of Drug Delivery Science and Technology 63, pages 102442.
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Guohua Ren & Ying Zhao. (2021) Preparation methods and thermal stability of calcipotriol solid lipid nanoparticles and efficacy in plaque psoriasis treatment. Journal of Thermal Analysis and Calorimetry 144:6, pages 2091-2098.
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Nishu Yadav, Rohan Aggarwal, Monika Targhotra, Prabhat K. Sahoo & Meenakshi K. Chauhan. (2021) Natural and Nanotechnology Based Treatment: An Alternative Approach to Psoriasis. Current Nanomedicine 11:1, pages 21-39.
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Robert Gironés Petit, Amanda Cano, Alba Ortiz, Marta Espina, Josefina Prat, Montserrat Muñoz, Patrícia Severino, Eliana B. Souto, Maria L. García, Montserrat Pujol & Elena Sánchez-López. (2021) Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics. International Journal of Molecular Sciences 22:9, pages 4983.
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Sujata Pralhad Sawarkar & Vijay Yadav. (2021) Novel drug delivery strategies and gene therapy regimen as a promising perspective for management of psoriasis. Indian Journal of Dermatology, Venereology and Leprology 87, pages 333-340.
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Medha Bhat, Sudeep Pukale, Saurabh Singh, Anupama Mittal & Deepak Chitkara. (2021) Nano-enabled topical delivery of anti-psoriatic small molecules. Journal of Drug Delivery Science and Technology 62, pages 102328.
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Parinbhai Shah, Benjamin Goodyear, Nirali Dholaria, Vinam Puri & Bozena Michniak-Kohn. (2021) Nanostructured Non-Ionic Surfactant Carrier-Based Gel for Topical Delivery of Desoximetasone. International Journal of Molecular Sciences 22:4, pages 1535.
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Madhulika Pradhan, Krishna Yadav, Deependra Singh & Manju Rawat Singh. (2021) Topical delivery of fluocinolone acetonide integrated NLCs and salicylic acid enriched gel: A potential and synergistic approach in the management of psoriasis. Journal of Drug Delivery Science and Technology 61, pages 102282.
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Madhulika Pradhan, Amit Alexander, Manju Rawat Singh, Deependra Singh, Swarnlata Saraf, Shailendra Saraf, Krishna Yadav & Ajazuddin. (2021) Statistically optimized calcipotriol fused nanostructured lipid carriers for effectual topical treatment of psoriasis. Journal of Drug Delivery Science and Technology 61, pages 102168.
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Nupur Shrivastava, Ankit Parikh, Aiswarya Chaudhuri, Javed Ali, Sanjula Baboota & Sanjay Garg. 2021. Nanocarriers for the Delivery of Combination Drugs. Nanocarriers for the Delivery of Combination Drugs 259 305 .
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Navjot Kaur, Manjot Kaur, Manishi Mahajan & Subheet Kumar Jain. (2020) Development, characterization and evaluation of nanocarrier based formulations of antipsoriatic drug “acitretin” for skin targeting. Journal of Drug Delivery Science and Technology 60, pages 102010.
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Sebastián Scioli Montoto, Giuliana Muraca & María Esperanza Ruiz. (2020) Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects. Frontiers in Molecular Biosciences 7.
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Sudeep Sudesh Pukale, Saurabh Sharma, Manu Dalela, Arihant kumar Singh, Sujata Mohanty, Anupama Mittal & Deepak Chitkara. (2020) Multi-component clobetasol-loaded monolithic lipid-polymer hybrid nanoparticles ameliorate imiquimod-induced psoriasis-like skin inflammation in Swiss albino mice. Acta Biomaterialia 115, pages 393-409.
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Vamshi Krishna Rapalli, Vedhant Kaul, Tejashree Waghule, Srividya Gorantla, Swati Sharma, Aniruddha Roy, Sunil Kumar Dubey & Gautam Singhvi. (2020) Curcumin loaded nanostructured lipid carriers for enhanced skin retained topical delivery: optimization, scale-up, in-vitro characterization and assessment of ex-vivo skin deposition. European Journal of Pharmaceutical Sciences 152, pages 105438.
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Ana M. Martins, Andreia Ascenso, Helena Margarida Ribeiro & Joana Marto. (2020) Current and Future Therapies for Psoriasis with a Focus on Serotonergic Drugs. Molecular Neurobiology 57:5, pages 2391-2419.
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Mohammed S. Algahtani, Mohammad Zaki Ahmad & Javed Ahmad. (2020) Nanoemulgel for Improved Topical Delivery of Retinyl Palmitate: Formulation Design and Stability Evaluation. Nanomaterials 10:5, pages 848.
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Fahad Pervaiz, Madiha Saleem, Akram Ashames, Sahrish Rehmani, Rubina Qaiser, Sobia Noreen & Ghulam Murtaza. (2020) Development and ex-vivo skin permeation studies of finasteride–poly(lactic acid- co -glycolic acid) and minoxidil–chitosan nanoparticulate systems . Journal of Bioactive and Compatible Polymers 35:2, pages 77-91.
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Bo Song, Ruiteng Song, Min Cheng, Hairong Chu, Fang Yan & Yuzhen Wang. (2019) Preparation of Calcipotriol Emulsion Using Bacterial Exopolysaccharides as Emulsifier for Percutaneous Treatment of Psoriasis Vulgaris. International Journal of Molecular Sciences 21:1, pages 77.
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Sara Salatin, Jaleh BararMohammad Barzegar-JalaliKhosro AdibkiaMitra Alami-MilaniMitra Jelvehgari. (2019) Formulation and Evaluation of Eudragit RL-100 Nanoparticles Loaded In-Situ Forming Gel for Intranasal Delivery of Rivastigmine. Advanced Pharmaceutical Bulletin 10:1, pages 20-29.
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Vamshi Krishna Rapalli, Gautam Singhvi, Sunil Kumar Dubey, Gaurav Gupta, Dinesh Kumar Chellappan & Kamal Dua. (2018) Emerging landscape in psoriasis management: From topical application to targeting biomolecules. Biomedicine & Pharmacotherapy 106, pages 707-713.
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