545
Views
33
CrossRef citations to date
0
Altmetric
Original Research

Enhancement of oral insulin bioavailability: in vitro and in vivo assessment of nanoporous stimuli-responsive hydrogel microparticles

, , &
Pages 621-632 | Received 14 Sep 2015, Accepted 17 Feb 2016, Published online: 24 Mar 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Boris Odelion Pichihua Pardo, Adalberto Pessoa Junior, Marco Antônio Stephano & Laura de Oliveira-Nascimento. (2020) Protein drug delivery: current dosage form profile and formulation strategies. Journal of Drug Targeting 28:4, pages 339-355.
Read now
Shiming He, Zhongcheng Liu & Donggang Xu. (2019) Advance in oral delivery systems for therapeutic protein. Journal of Drug Targeting 27:3, pages 283-291.
Read now
Lin Liu, WenDong Yao, YueFeng Rao, XiaoYang Lu & JianQing Gao. (2017) pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms. Drug Delivery 24:1, pages 569-581.
Read now

Articles from other publishers (30)

Chen Xie, Qiansha Luo, Yuxuan Zhang, Fang Qin, Yingfeng Tu & Kun Liu. (2023) Micro/Nanomotors for Oral Delivery of Drugs: From Design to Application. Advanced NanoBiomed Research.
Crossref
Kedong Liu, Yun Chen, Zhaoqi Yang & Jian Jin. (2023) Preparation and characterization of CS/γ-PGA/PC complex nanoparticles for insulin oral delivery. Colloid and Polymer Science 301:5, pages 481-490.
Crossref
Mehrab Pourmadadi, Arian Farokh, Erfan Rahmani, Mohammad Mahdi Eshaghi, Ali Aslani, Abbas Rahdar & Luiz Fernando Romanholo Ferreira. (2023) Polyacrylic acid mediated targeted drug delivery nano-systems: A review. Journal of Drug Delivery Science and Technology 80, pages 104169.
Crossref
Deepak A. Subramanian, Robert Langer & Giovanni Traverso. (2022) Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems. Journal of Nanobiotechnology 20:1.
Crossref
Chunxiang Mo, Rui Luo & Yuping Chen. (2022) Advances in the Stimuli‐Responsive Injectable Hydrogel for Controlled Release of Drugs. Macromolecular Rapid Communications 43:10, pages 2200007.
Crossref
Jung Seok Lee, Patrick Han, Rabib Chaudhury, Shihan Khan, Sean Bickerton, Michael D. McHugh, Hyun Bong Park, Alyssa L. Siefert, Gerald Rea, José M. Carballido, David A. Horwitz, Jason Criscione, Karlo Perica, Robert Samstein, Ragy Ragheb, Dongin Kim & Tarek M. Fahmy. (2021) Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin. Nature Biomedical Engineering 5:9, pages 983-997.
Crossref
Andréia Bagliotti Meneguin, Amanda Letícia Polli Silvestre, Larissa Sposito, Maurício Palmeira Chaves de Souza, Rafael Miguel Sábio, Victor Hugo Sousa Araújo, Beatriz Stringhetti Ferreira Cury & Marlus Chorilli. (2021) The role of polysaccharides from natural resources to design oral insulin micro- and nanoparticles intended for the treatment of Diabetes mellitus: A review. Carbohydrate Polymers 256, pages 117504.
Crossref
Manuel Palencia, Arturo Espinosa-Duque, Andrés Otálora & Angélica García-Quintero. 2021. Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine. Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine 423 470 .
Amanina Setapa, Naveed Ahmad, Shalela Mohd Mahali & Mohd Cairul Iqbal Mohd Amin. (2020) Mathematical Model for Estimating Parameters of Swelling Drug Delivery Devices in a Two-Phase Release. Polymers 12:12, pages 2921.
Crossref
Fatemah Bahman, Sebastien Taurin, Diab Altayeb, Safa Taha, Moiz Bakhiet & Khaled Greish. (2020) Oral Insulin Delivery Using Poly (Styrene Co-Maleic Acid) Micelles in a Diabetic Mouse Model. Pharmaceutics 12:11, pages 1026.
Crossref
Yunhua Zhong, Bo Song, Dan He, Zemei Xia, Peng Wang, Junzi Wu & Yan Li. (2020) Galactose-based polymer-containing phenylboronic acid as carriers for insulin delivery. Nanotechnology 31:39, pages 395601.
Crossref
Daniel J. Drucker. (2019) Advances in oral peptide therapeutics. Nature Reviews Drug Discovery 19:4, pages 277-289.
Crossref
Naveed Ahmad, Manisha Pandey, Najwa Mohamad, Xiang Yi Chen & Mohd Cairul Iqbal Mohd Amin. 2020. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems 441 474 .
Tiago Carvalho, Gabriela Guedes, Filipa L. Sousa, Carmen S. R. Freire & Hélder A. Santos. (2019) Latest Advances on Bacterial Cellulose‐Based Materials for Wound Healing, Delivery Systems, and Tissue Engineering. Biotechnology Journal 14:12, pages 1900059.
Crossref
Xiang Yi Chen, Adeel Masood Butt & Mohd Cairul Iqbal Mohd Amin. (2019) Enhanced paracellular delivery of vaccine by hydrogel microparticles-mediated reversible tight junction opening for effective oral immunization. Journal of Controlled Release 311-312, pages 50-64.
Crossref
Xiang Yi Chen, Adeel Masood Butt & Mohd Cairul Iqbal Mohd Amin. (2019) Molecular Evaluation of Oral Immunogenicity of Hepatitis B Antigen Delivered by Hydrogel Microparticles. Molecular Pharmaceutics 16:9, pages 3853-3872.
Crossref
Yan Fang, Qi Wang, Xiaojie Lin, Xuechao Jin, Dongjuan Yang, Shan Gao, Xiyan Wang, Mingshi Yang & Kai Shi. (2019) Gastrointestinal Responsive Polymeric Nanoparticles for Oral Delivery of Insulin: Optimized Preparation, Characterization, and In Vivo Evaluation. Journal of Pharmaceutical Sciences 108:9, pages 2994-3002.
Crossref
Fatemah Bahman, Khaled Greish & Sebastien Taurin. (2019) Nanotechnology in Insulin Delivery for Management of Diabetes. Pharmaceutical Nanotechnology 7:2, pages 113-128.
Crossref
Jingying Liu, Ulrich Werner, Mario Funke, Melissa Besenius, Lasse Saaby, Mathias Fanø, Huiling Mu & Anette Müllertz. (2019) SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats. International Journal of Pharmaceutics 560, pages 377-384.
Crossref
Taradokht Alavi, Masoud Rezvanian, Naveed Ahmad, Najwa Mohamad & Shiow-Fern Ng. (2017) Pluronic-F127 composite film loaded with erythromycin for wound application: formulation, physicomechanical and in vitro evaluations. Drug Delivery and Translational Research 9:2, pages 508-519.
Crossref
Chun Y. Wong, Jorge Martinez, Hani Al-Salami & Crispin R. Dass. (2018) Quantification of BSA-loaded chitosan/oligonucleotide nanoparticles using reverse-phase high-performance liquid chromatography. Analytical and Bioanalytical Chemistry 410:27, pages 6991-7006.
Crossref
Chayanika Deka, Deepanwita Deka, Montu Moni Bora, Dhruva Kumar Jha & Dilip Kumar Kakati. (2018) Investigation of pH-Sensitive Swelling and Curcumin Release Behavior of Chitglc Hydrogel. Journal of Polymers and the Environment 26:10, pages 4034-4045.
Crossref
Jordan D. Lewicky, Alexandrine L. Martel, Nya L. Fraleigh, Amanda Boraman, Thi M.-D. Nguyen, Peter W. Schiller, Tze Chieh Shiao, René Roy & Hoang-Thanh Le. (2018) Strengthening peptide-based drug activity with novel glyconanoparticle. PLOS ONE 13:9, pages e0204472.
Crossref
Na Ji, Yan Hong, Zhengbiao Gu, Li Cheng, Zhaofeng Li & Caiming Li. (2018) Preparation and Characterization of Insulin-Loaded Zein/Carboxymethylated Short-Chain Amylose Complex Nanoparticles. Journal of Agricultural and Food Chemistry 66:35, pages 9335-9343.
Crossref
Chun Y. Wong, Hani Al-Salami & Crispin R. Dass. (2018) Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin. International Journal of Pharmaceutics 537:1-2, pages 223-244.
Crossref
Carla M. Lopes, Pedro Barata & Rita Oliveira. 2018. Drug Targeting and Stimuli Sensitive Drug Delivery Systems. Drug Targeting and Stimuli Sensitive Drug Delivery Systems 155 209 .
Stine Harloff-Helleberg, Line Hagner Nielsen & Hanne Mørck Nielsen. (2017) Animal models for evaluation of oral delivery of biopharmaceuticals. Journal of Controlled Release 268, pages 57-71.
Crossref
Na Ji, Yan Hong, Zhengbiao Gu, Li Cheng, Zhaofeng Li & Caiming Li. (2017) Binary and Tertiary Complex Based on Short-Chain Glucan and Proanthocyanidins for Oral Insulin Delivery. Journal of Agricultural and Food Chemistry 65:40, pages 8866-8874.
Crossref
Ester Caffarel-Salvador, Alex Abramson, Robert Langer & Giovanni Traverso. (2017) Oral delivery of biologics using drug-device combinations. Current Opinion in Pharmacology 36, pages 8-13.
Crossref
Alejandro Sosnik & Katia Seremeta. (2017) Polymeric Hydrogels as Technology Platform for Drug Delivery Applications. Gels 3:3, pages 25.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.