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Expert Opinion on Drug Delivery Volume 3, 2006 - Issue 2
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Review

Role of calcium in gene delivery

Vijay I Kulkarni Research Scholar, Centre for Postgraduate Studies and Research, New Drug Delivery Systems laboratory, Pharmacy Department, Donors Plaza, MS University of Baroda, Fatehgunj, Vadodara – 390 002, India. [email protected]
,
Vikram S Shenoy Research Scholar, Centre for Postgraduate Studies and Research, New Drug Delivery Systems laboratory, Pharmacy Department, Donors Plaza, MS University of Baroda, Fatehgunj, Vadodara – 390 002, India
,
Shamsunder S Dodiya Research Scholar, Centre for Postgraduate Studies and Research, New Drug Delivery Systems laboratory, Pharmacy Department, Donors Plaza, MS University of Baroda, Fatehgunj, Vadodara – 390 002, India
,
Tushar H Rajyaguru Research Scholar, Centre for Postgraduate Studies and Research, New Drug Delivery Systems laboratory, Pharmacy Department, Donors Plaza, MS University of Baroda, Fatehgunj, Vadodara – 390 002, India
&
Rayasa R Murthy Professor in Pharmaceutics, Centre for Postgraduate Studies and Research, New Drug Delivery Systems laboratory, Pharmacy Department, Donors Plaza, MS University of Baroda, Fatehgunj, Vadodara – 390 002, India
Pages 235-245 | Published online: 28 Feb 2006

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Szu-Yuan Wu, Li-Ting Chang, Sydeny Peng & Hsieh-Chih Tsai. (2015) Calcium-activated gene transfection from DNA/poly(amic acid-co-imide) complexes. International Journal of Nanomedicine 10, pages 1637-1647.
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Articles from other publishers (25)

Vipin V. Dhote, Prem Samundre, Aman B. Upaganlawar & Aditya Ganeshpurkar. (2023) Gene Therapy for Chronic Traumatic Brain Injury: Challenges in Resolving Long-term Consequences of Brain Damage. Current Gene Therapy 23:1, pages 3-19.
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Linjia Su, Zhe Sun, Fangzheng Qi, Huishan Su, Luomeng Qian, Jing Li, Liang Zuo, Jinhai Huang, Zhilin Yu, Jinping Li, Zhinan Chen & Sihe Zhang. (2022) GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer. Journal of Nanobiotechnology 20:1.
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Hong-Chao Sun, Jing Huang, Yuan Fu, Li-Li Hao, Xin Liu & Tuan-Yuan Shi. (2021) Enhancing Immune Responses to a DNA Vaccine Encoding Toxoplasma gondii GRA7 Using Calcium Phosphate Nanoparticles as an Adjuvant. Frontiers in Cellular and Infection Microbiology 11.
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Aniket Wahane, Shipra Malik, Kuo-Chih Shih, Ravinder Reddy Gaddam, Chaohao Chen, Yun Liu, Mu-Ping Nieh, Ajit Vikram & Raman Bahal. (2021) Dual-Modality Poly- l -histidine Nanoparticles to Deliver Peptide Nucleic Acids and Paclitaxel for In Vivo Cancer Therapy . ACS Applied Materials & Interfaces 13:38, pages 45244-45258.
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Coralie Bellefroid, Anna Lechanteur, Brigitte Evrard & Géraldine Piel. (2019) Lipid gene nanocarriers for the treatment of skin diseases: Current state-of-the-art. European Journal of Pharmaceutics and Biopharmaceutics 137, pages 95-111.
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Yeon Su Choi, Kyoungnam Kim, Kitae Ryu, Hana Cho, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Byung Gon Kim, Soo Chang Song & Han Chang Kang. (2018) Dual-functionalized calcium nanocomplexes for transfection of cancerous and stem cells: Low molecular weight polycation-mediated colloidal stability and ATP-mediated endosomal release. Journal of Industrial and Engineering Chemistry 64, pages 300-310.
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Sheng-Xue Xie, Abdulgader A. Baoum, Nabil A. Alhakamy & Cory J. Berkland. (2018) Calcium enhances gene expression when using low molecular weight poly-l-lysine delivery vehicles. International Journal of Pharmaceutics 547:1-2, pages 274-281.
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Efrat Korin, Tzlil Bejerano & Smadar Cohen. (2017) GalNAc bio-functionalization of nanoparticles assembled by electrostatic interactions improves siRNA targeting to the liver. Journal of Controlled Release 266, pages 310-320.
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Wenpan Li, Xiu Xin, Shasha Jing, Xirui Zhang, Kang Chen, Dawei Chen & Haiyang Hu. (2017) Organic metal complexes based on zoledronate–calcium: a potential pDNA delivery system. Journal of Materials Chemistry B 5:8, pages 1601-1610.
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Matan Goldshtein, Efrat Forti, Emil Ruvinov & Smadar Cohen. (2016) Mechanisms of cellular uptake and endosomal escape of calcium-siRNA nanocomplexes. International Journal of Pharmaceutics 515:1-2, pages 46-56.
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Emil Ruvinov, Olga Kryukov, Efrat Forti, Efrat Korin, Matan Goldstein & Smadar Cohen. (2015) Calcium–siRNA nanocomplexes: What reversibility is all about. Journal of Controlled Release 203, pages 150-160.
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Ana L. Barrán-Berdón, Belén Yélamos, Marc Malfois, Emilio Aicart & Elena Junquera. (2014) Ca 2+ -Mediated Anionic Lipid–Plasmid DNA Lipoplexes. Electrochemical, Structural, and Biochemical Studies . Langmuir 30:39, pages 11704-11713.
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Alberto Martín-Molina, Germán Luque-Caballero, Jordi Faraudo, Manuel Quesada-Pérez & Julia Maldonado-Valderrama. (2014) Adsorption of DNA onto anionic lipid surfaces. Advances in Colloid and Interface Science 206, pages 172-185.
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Min Feng, Basma M. Ibrahim, Erin M. Wilson, Kyung-Oh Doh, Brandon K. Bergman, Christopher Park & Yoon Yeo. (2014) Stabilization of a hyaluronate-associated gene delivery system using calcium ions. Biomater. Sci. 2:6, pages 936-942.
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Mengjie Rui, Hailing Tang, Yan Li, Xiaohui Wei & Yuhong Xu. (2012) Recombinant High Density Lipoprotein Nanoparticles for Target-Specific Delivery of siRNA. Pharmaceutical Research 30:5, pages 1203-1214.
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Mamta Kapoor & Diane J. Burgess. (2012) Cellular Uptake Mechanisms of Novel Anionic siRNA Lipoplexes. Pharmaceutical Research 30:4, pages 1161-1175.
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Mamta Kapoor & Diane J. Burgess. (2012) Efficient and safe delivery of siRNA using anionic lipids: Formulation optimization studies. International Journal of Pharmaceutics 432:1-2, pages 80-90.
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Giovanna Grandinetti, Adam E. Smith & Theresa M. Reineke. (2012) Membrane and Nuclear Permeabilization by Polymeric pDNA Vehicles: Efficient Method for Gene Delivery or Mechanism of Cytotoxicity?. Molecular Pharmaceutics 9:3, pages 523-538.
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Amra Tabaković, Mark Kester & James H. Adair. (2011) Calcium phosphate‐based composite nanoparticles in bioimaging and therapeutic delivery applications. WIREs Nanomedicine and Nanobiotechnology 4:1, pages 96-112.
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Daniel A. Balazs & WT. Godbey. (2011) Liposomes for Use in Gene Delivery. Journal of Drug Delivery 2011, pages 1-12.
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O. A. Pinto, A. Tabaković, T. M. Goff, Y. Liu & J. H. Adair. 2011. Intracellular Delivery. Intracellular Delivery 713 744 .
Atul Pathak, Soma Patnaik & Kailash Chand Gupta. (2009) Recent trends in non-viral vector-mediated gene delivery. Biotechnology Journal 4:11, pages 1559-1572.
Crossref
Claudio E. Pedraza, David C. Bassett, Marc D. McKee, Valentin Nelea, Uwe Gbureck & Jake E. Barralet. (2008) The importance of particle size and DNA condensation salt for calcium phosphate nanoparticle transfection. Biomaterials 29:23, pages 3384-3392.
Crossref
Gennady B. Khomutov. 2008. Nanomaterials for Application in Medicine and Biology. Nanomaterials for Application in Medicine and Biology 39 57 .
M. Reza Mozafari & Abdelwahab Omri. (2007) Importance of divalent cations in nanolipoplex gene delivery. Journal of Pharmaceutical Sciences 96:8, pages 1955-1966.
Crossref

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