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Review

Nanodisks: hydrophobic drug delivery vehicles

, PhD
Pages 343-351 | Published online: 05 Mar 2008

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Gabriel Silva Marques Borges, Flávia Alves Lima, Guilherme Carneiro, Gisele Assis Castro Goulart & Lucas Antônio Miranda Ferreira. (2021) All-trans retinoic acid in anticancer therapy: how nanotechnology can enhance its efficacy and resolve its drawbacks. Expert Opinion on Drug Delivery 18:10, pages 1335-1354.
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Ahmed O. Elzoghby, Omar Samir, Ahmed Soliman, Sergey Solomevich, Minzhi Yu, Anna Schwendeman & Mahmoud L. Nasr. (2023) Nanodiscs: Game changer nano-therapeutics and structural biology tools. Nano Today 53, pages 102026.
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Colin A. Fox & Robert O. Ryan. (2022) Studies of the cardiolipin interactome. Progress in Lipid Research, pages 101195.
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Ekaterina Kostyurina, Jürgen Allgaier, Margarita Kruteva, Henrich Frielinghaus, Agnes Csiszár, Stephan Förster & Ralf Biehl. (2022) Passive Macromolecular Translocation Mechanism through Lipid Membranes. Journal of the American Chemical Society 144:33, pages 15348-15354.
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Anthony Moschetti, Colin A. Fox, Samuel McGowen & Robert O. Ryan. (2022) Lutein nanodisks protect human retinal pigment epithelial cells from UV light-induced damage. Frontiers in Nanotechnology 4.
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Jitender Bariwal, Hairong Ma, Guillermo A. Altenberg & Hongjun Liang. (2022) Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment. Chemical Society Reviews 51:5, pages 1702-1728.
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Kyle Lethcoe, Colin A. Fox & Robert O. Ryan. (2022) Foam fractionation of a recombinant biosurfactant apolipoprotein. Journal of Biotechnology 343, pages 25-31.
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Colin A. Fox, Anthony Moschetti & Robert O. Ryan. (2021) Reconstituted HDL as a therapeutic delivery device. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1866:11, pages 159025.
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Anthony Moschetti, Ruben K. Dagda & Robert O. Ryan. (2021) Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine: Nanotechnology, Biology and Medicine 37, pages 102439.
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Veronica Bensa, Enzo Calarco, Elena Giusto, Patrizia Perri, Maria Valeria Corrias, Mirco Ponzoni, Chiara Brignole & Fabio Pastorino. (2021) Retinoids Delivery Systems in Cancer: Liposomal Fenretinide for Neuroectodermal-Derived Tumors. Pharmaceuticals 14:9, pages 854.
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Hyunseok Oh, Younghun Jung, Seokoh Moon, Jaehyeon Hwang, Choongjin Ban, Jinhyo Chung, Woo-Jae Chung & Dae-Hyuk Kweon. (2021) Development of End-Spliced Dimeric Nanodiscs for the Improved Virucidal Activity of a Nanoperforator. ACS Applied Materials & Interfaces 13:31, pages 36757-36768.
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Aditya Gupta, Reena Sharma, Kaushik Kuche & Sanyog Jain. (2021) Exploring the therapeutic potential of the bioinspired reconstituted high density lipoprotein nanostructures. International Journal of Pharmaceutics 596, pages 120272.
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Masafumi Tanaka, Hisayasu Miyake, Satoko Oka, Shintaro Maeda, Kenji Iwasaki & Takahiro Mukai. (2020) Effects of charged lipids on the physicochemical and biological properties of lipid–styrene maleic acid copolymer discoidal particles. Biochimica et Biophysica Acta (BBA) - Biomembranes 1862:5, pages 183209.
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Anthony Moschetti, Lucas N. Vine, Kyle Lethcoe, Ruben K. Dagda, Patricia Ellison & Robert O. Ryan. (2020) Assembly and Characterization of Biocompatible Coenzyme Q 10 ‐Enriched Lipid Nanoparticles . Lipids 55:2, pages 141-149.
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Konstantin A. Okotrub, Valeriya A. Zykova, Sergey V. Adichtchev & Nikolay V. Surovtsev. (2020) Deciphering the orientation of lipid molecules by principal component analysis of Raman mapping data. The Analyst 145:4, pages 1466-1472.
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Hyungjin Kim, Tomohiro Nobeyama, Shinnosuke Honda, Kaori Yasuda, Nobuhiro Morone & Tatsuya Murakami. (2019) Membrane fusogenic high-density lipoprotein nanoparticles. Biochimica et Biophysica Acta (BBA) - Biomembranes 1861:10, pages 183008.
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Byoungjae Kong, Seokoh Moon, Yuna Kim, Paul Heo, Younghun Jung, Seok-Hyeon Yu, Jinhyo Chung, Choongjin Ban, Yong Ho Kim, Paul Kim, Beom Jeung Hwang, Woo-Jae Chung, Yeon-Kyun Shin, Baik Lin Seong & Dae-Hyuk Kweon. (2019) Virucidal nano-perforator of viral membrane trapping viral RNAs in the endosome. Nature Communications 10:1.
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Vandana Soni, Silki Chandel, Vikas Pandey, Saket Asati, Priyanka Jain, Aviral Jain & Rakesh K. Tekade. 2019. Biomaterials and Bionanotechnology. Biomaterials and Bionanotechnology 263 300 .
Ravi Kant Upadhyay. (2018) Lipoproteins as drug delivery vehicles for cancer and tumor therapeutics. Journal of Stem Cell Research & Therapeutics 4:3.
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Mariana C. Fiori, Yunjiang Jiang, Wan Zheng, Miguel Anzaldua, Mario J. Borgnia, Guillermo A. Altenberg & Hongjun Liang. (2017) Polymer Nanodiscs: Discoidal Amphiphilic Block Copolymer Membranes as a New Platform for Membrane Proteins. Scientific Reports 7:1.
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Thirupathi Ravula, Nathaniel Z. Hardin, Sudheer Kumar Ramadugu & Ayyalusamy Ramamoorthy. (2017) pH Tunable and Divalent Metal Ion Tolerant Polymer Lipid Nanodiscs. Langmuir 33:40, pages 10655-10662.
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Nikita Ikon, Jennifer Shearer, Jianfang Liu, Jesse J. Tran, ShiBo Feng, Ayako Kamei, Jennifer A. Beckstead, Robert S. Kiss, Paul M. Weers, Gang Ren & Robert O. Ryan. (2017) A facile method for isolation of recombinant human apolipoprotein A-I from E. coli. Protein Expression and Purification 134, pages 18-24.
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Ilia G. Denisov & Stephen G. Sligar. (2017) Nanodiscs in Membrane Biochemistry and Biophysics. Chemical Reviews 117:6, pages 4669-4713.
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Dick J. Van der Horst & Robert O. Ryan. 2017. Reference Module in Life Sciences. Reference Module in Life Sciences.
Nahal R. Lalefar, Andrzej Witkowski, Jens B. Simonsen & Robert O. Ryan. (2016) Wnt3a nanodisks promote ex vivo expansion of hematopoietic stem and progenitor cells. Journal of Nanobiotechnology 14:1.
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Natasha M. CrosbyMistuni GhoshBetty SuJennifer A. BecksteadAyako KameiJens B. SimonsenBing LuoLeo I. GordonTrudy M. ForteRobert O. Ryan. (2015) Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks promote targeted bioactive agent delivery to CD20-positive lymphomas. Biochemistry and Cell Biology 93:4, pages 343-350.
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Nikita Ikon, Betty Su, Fong-Fu Hsu, Trudy M. Forte & Robert O. Ryan. (2015) Exogenous cardiolipin localizes to mitochondria and prevents TAZ knockdown-induced apoptosis in myeloid progenitor cells. Biochemical and Biophysical Research Communications 464:2, pages 580-585.
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Tatsuya Murakami, Haruki Okamoto & Hyungjin Kim. (2015) Internalization of High-density Lipoproteins Bearing Arginine-rich Peptides. Chemistry Letters 44:3, pages 336-338.
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Tatsuya Murakami, Haruki Okamoto & Hyungjin Kim. (2015) Structural and functional changes in high-density lipoprotein induced by chemical modification. Biomaterials Science 3:5, pages 712-715.
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Ramachandran S. Santhosh & Visamsetti Amarendra. 2015. Hb25_Springer Handbook of Marine Biotechnology. Hb25_Springer Handbook of Marine Biotechnology 1113 1129 .
Mistuni Ghosh & Robert O. Ryan. (2014) Curcumin homing to the nucleolus: mechanism for initiation of an apoptotic program. The Journal of Nutritional Biochemistry 25:11, pages 1117-1123.
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Daniel C. Buehler, Matthew D. Marsden, Sean Shen, Daniel B. Toso, Xiaomeng Wu, Joseph A. Loo, Z. Hong Zhou, Valerie A. Kickhoefer, Paul A. Wender, Jerome A. Zack & Leonard H. Rome. (2014) Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery. ACS Nano 8:8, pages 7723-7732.
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Mistuni GhoshGang RenJens B. SimonsenRobert O. Ryan. (2014) Cationic lipid nanodisks as an siRNA delivery vehicle. Biochemistry and Cell Biology 92:3, pages 200-205.
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Mistuni Ghosh & Robert O Ryan. (2014) ApoE enhances nanodisk-mediated curcumin delivery to glioblastoma multiforme cells. Nanomedicine 9:6, pages 763-771.
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Dina R. Weilhammer, Craig D. Blanchette, Nicholas O. Fischer, Shabnam Alam, Gabriela G. Loots, Michele Corzett, Cynthia Thomas, Cheri Lychak, Alexis D. Dunkle, Joyce J. Ruitenberg, Smita A. Ghanekar, Andrea J. Sant & Amy Rasley. (2013) The use of nanolipoprotein particles to enhance the immunostimulatory properties of innate immune agonists against lethal influenza challenge. Biomaterials 34:38, pages 10305-10318.
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Wei He, Juntao Luo, Feliza Bourguet, Li Xing, Sun K. Yi, Tingjuan Gao, Craig Blanchette, Paul T. Henderson, Edward Kuhn, Mike Malfatti, William J. Murphy, R. Holland Cheng, Kit S. Lam & Matthew A. Coleman. (2013) Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Science 22:8, pages 1078-1086.
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Marina G. Damiano, R. Kannan Mutharasan, Sushant Tripathy, Kaylin M. McMahon & C. Shad Thaxton. (2013) Templated high density lipoprotein nanoparticles as potential therapies and for molecular delivery. Advanced Drug Delivery Reviews 65:5, pages 649-662.
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Leonard H. Rome & Valerie A. Kickhoefer. (2012) Development of the Vault Particle as a Platform Technology. ACS Nano 7:2, pages 889-902.
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Nicholas O. Fischer, Amy Rasley, Michele Corzett, Mona H. Hwang, Paul D. Hoeprich & Craig D. Blanchette. (2013) Colocalized Delivery of Adjuvant and Antigen Using Nanolipoprotein Particles Enhances the Immune Response to Recombinant Antigens. Journal of the American Chemical Society 135:6, pages 2044-2047.
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Junting Jia, Yan Xiao, Jianping Liu, Wenli Zhang, Hongliang He, Liang Chen & Mengyuan Zhang. (2012) Preparation, Characterizations, and In Vitro Metabolic Processes of Paclitaxel-Loaded Discoidal Recombinant High-Density Lipoproteins. Journal of Pharmaceutical Sciences 101:8, pages 2900-2908.
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Tatsuya Murakami. (2012) Phospholipid nanodisc engineering for drug delivery systems. Biotechnology Journal 7:6, pages 762-767.
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Dick J Van der Horst & Robert O Ryan. 2012. Insect Molecular Biology and Biochemistry. Insect Molecular Biology and Biochemistry 317 345 .
S. Maya, M. Sabitha, Shantikumar V. Nair & R. Jayakumar. 2013. Multifaceted Development and Application of Biopolymers for Biology, Biomedicine and Nanotechnology. Multifaceted Development and Application of Biopolymers for Biology, Biomedicine and Nanotechnology 203 239 .
Sonny Ly, Jitka Petrlova, Thomas Huser, Samantha Fore, Tingjuan Gao, John Voss & Ted?A. Laurence. (2011) Stoichiometry of Reconstituted High-Density Lipoproteins in the Hydrated State Determined by Photon Antibunching. Biophysical Journal 101:4, pages 970-975.
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Renuka Sriram, Jens O. Lagerstedt, Jitka Petrlova, Haris Samardzic, Ulrike Kreutzer, Hongtao Xie, George A. Kaysen, Jean F. Desreux, David Thonon, Vincent Jacques, Martha Van Loan, John C. Rutledge, Michael N. Oda, John C. Voss & Thomas Jue. (2011) Imaging apolipoprotein AI in vivo . NMR in Biomedicine 24:7, pages 916-924.
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Mistuni Ghosh, Amareshwar T.K. Singh, Wenwei Xu, Todd Sulchek, Leo I. Gordon & Robert O. Ryan. (2011) Curcumin nanodisks: formulation and characterization. Nanomedicine: Nanotechnology, Biology and Medicine 7:2, pages 162-167.
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Arnida, M.M. Jan?t-Amsbury, A. Ray, C.M. Peterson & H. Ghandehari. (2011) Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages. European Journal of Pharmaceutics and Biopharmaceutics 77:3, pages 417-423.
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Kaylin M. McMahon, R. Kannan Mutharasan, Sushant Tripathy, Dorina Veliceasa, Mariana Bobeica, Dale K. Shumaker, Andrea J. Luthi, Brian T. Helfand, Hossein Ardehali, Chad A. Mirkin, Olga Volpert & C. Shad Thaxton. (2011) Biomimetic High Density Lipoprotein Nanoparticles For Nucleic Acid Delivery. Nano Letters 11:3, pages 1208-1214.
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Nicholas O. Fischer, Ernesto Infante, Tomohiro Ishikawa, Craig D. Blanchette, Nigel Bourne, Paul D. Hoeprich & Peter W. Mason. (2010) Conjugation to Nickel-Chelating Nanolipoprotein Particles Increases the Potency and Efficacy of Subunit Vaccines to Prevent West Nile Encephalitis. Bioconjugate Chemistry 21:6, pages 1018-1022.
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Amareshwar T.K. Singh, Andrew M. Evens, Reilly J. Anderson, Jennifer A. Beckstead, Natesan Sankar, Antonella Sassano, Savita Bhalla, Shuo Yang, Leonidas C. Platanias, Trudy M. Forte, Robert O. Ryan & Leo I. Gordon. (2010) All trans retinoic acid nanodisks enhance retinoic acid receptor mediated apoptosis and cell cycle arrest in mantle cell lymphoma. British Journal of Haematology, pages no-no.
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Arnida, Alexander Malugin & Hamidreza Ghandehari. (2009) Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres. Journal of Applied Toxicology 30:3, pages 212-217.
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David M. Iovannisci, Jennifer A. Beckstead & Robert O. Ryan. (2009) Targeting nanodisks via a single chain variable antibody ? Apolipoprotein chimera. Biochemical and Biophysical Research Communications 379:2, pages 466-469.
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