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Review

M cell-targeted delivery of vaccines and therapeutics

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Pages 693-702 | Published online: 05 Jun 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Kan Kaneko, Arlene McDowell, Yasuyuki Ishii & Sarah Hook. (2018) Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy. Journal of Liposome Research 28:4, pages 296-304.
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Miao Wang, Zeqian Gao, Zhongwang Zhang, Li Pan & Yongguang Zhang. (2014) Roles of M cells in infection and mucosal vaccines. Human Vaccines & Immunotherapeutics 10:12, pages 3544-3551.
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Barbara C. Baudner & Derek T. O’Hagan. (2010) Bioadhesive delivery systems for mucosal vaccine delivery. Journal of Drug Targeting 18:10, pages 752-770.
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Xinlian Wang, Xinglong Gao, Liuxiang Wang, Jinhui Lin & Ying Liu. (2023) Advances of Nanotechnology Toward Vaccine Development Against Animal Infectious Diseases. Advanced Functional Materials 33:46.
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Ludivine Delon, Rachel J. Gibson, Clive A Prestidge & Benjamin Thierry. (2022) Mechanisms of uptake and transport of particulate formulations in the small intestine. Journal of Controlled Release 343, pages 584-599.
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Tien Le, Brian Aguilar, Joslyn L. Mangal & Abhinav P. Acharya. (2021) Oral drug delivery for immunoengineering. Bioengineering & Translational Medicine 7:1.
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Mekapogu Madakka, Nambi Rajesh & Jinka Rajeswari. 2020. Immunotherapy for Gastrointestinal Malignancies. Immunotherapy for Gastrointestinal Malignancies 17 39 .
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Mohammad Ariful Islam, Jannatul Firdous, Abu Zayed Md Badruddoza, Emma Reesor, Mohammad Azad, Anwarul Hasan, Michael Lim, Wuji Cao, Simon Guillemette & Chong Su Cho. (2019) M cell targeting engineered biomaterials for effective vaccination. Biomaterials 192, pages 75-94.
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A. B. Shreya, Sushil Yadaorao Raut, Renuka Suresh Managuli, Nayanabhirama Udupa & Srinivas Mutalik. (2018) Active Targeting of Drugs and Bioactive Molecules via Oral Administration by Ligand-Conjugated Lipidic Nanocarriers: Recent Advances. AAPS PharmSciTech 20:1.
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Jyotiranjan Bal, Hee-Young Jung, Luong Ngoc Nguyen, Jisang Park, Yong-Suk Jang & Dae-Hyuk Kim. (2018) Evaluation of cell-surface displayed synthetic consensus dengue EDIII cells as a potent oral vaccine candidate. Microbial Cell Factories 17:1.
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Tamiru Negash Alkie, Alexander Yitbarek, Khaled Taha-Abdelaziz, Jake Astill & Shayan Sharif. (2018) Characterization of immunogenicity of avian influenza antigens encapsulated in PLGA nanoparticles following mucosal and subcutaneous delivery in chickens. PLOS ONE 13:11, pages e0206324.
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Inam Ullah Khan, Jiansheng Huang, Rui Liu, Jingbo Wang, Jun Xie & Naishuo Zhu. (2017) Phage Display–Derived Ligand for Mucosal Transcytotic Receptor GP-2 Promotes Antigen Delivery to M Cells and Induces Antigen-Specific Immune Response. SLAS Discovery 22:7, pages 879-886.
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Xiangmei Fan, Yan Yue & Sidong Xiong. (2017) Incorporation of a bi-functional protein FimH enhances the immunoprotection of chitosan-pVP1 vaccine against coxsackievirus B3-induced myocarditis. Antiviral Research 140, pages 121-132.
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Mandeep Singh Bakshi & Gurinder Kaur Ahluwalia. 2017. Applications of Chalcogenides: S, Se, and Te. Applications of Chalcogenides: S, Se, and Te 263 283 .
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Andrew J. Broadbent, Kobporn Boonnak & Kanta Subbarao. 2015. Mucosal Immunology. Mucosal Immunology 1129 1170 .
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Sae-Hae Kim, Dae-Im Jung, In-Young Yang, Sun-Hee Jang, Ju Kim, Thang Thua Truong, Thuc Van Pham, Ninh Uyen Truong, Kyung-Yeol Lee & Yong-Suk Jang. (2013) Application of an M-cell-targeting ligand for oral vaccination induces efficient systemic and mucosal immune responses against a viral antigen. International Immunology 25:11, pages 623-632.
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Emma Louise Walton. (2013) A bacterium's guide to orienteering in the intestinal lumen. Microbes and Infection 15:13, pages 845-848.
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Sae-Hae Kim, In-Young Yang, Sun-Hee Jang, Ju Kim, Thang Thua Truong, Thuc Van Pham, Ninh Uyen Truong, Kyung-Yeol Lee & Yong-Suk Jang. (2013) C5a receptor-targeting ligand-mediated delivery of dengue virus antigen to M cells evokes antigen-specific systemic and mucosal immune responses in oral immunization. Microbes and Infection 15:13, pages 895-902.
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Joshua J. Reineke, Daniel Y. Cho, Yu-Ting Dingle, A. Peter MorelloIIIIII, Jules Jacob, Christopher G. Thanos & Edith Mathiowitz. (2013) Unique insights into the intestinal absorption, transit, and subsequent biodistribution of polymer-derived microspheres. Proceedings of the National Academy of Sciences 110:34, pages 13803-13808.
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Sae‐Hae Kim, Dae‐Im Jung, In‐Young Yang, Ju Kim, Kyung‐Yeol Lee, Tomonori Nochi, Hiroshi Kiyono & Yong‐Suk Jang. (2011) M cells expressing the complement C5a receptor are efficient targets for mucosal vaccine delivery. European Journal of Immunology 41:11, pages 3219-3229.
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Emilie Roger, Frederic Lagarce, Emmanuel Garcion & Jean-Pierre Benoit. (2010) Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomedicine 5:2, pages 287-306.
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