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Pharmacogenetics and the serotonin transporter in late-life depression

, MD MSW & , MD PhD FRCPC
Pages 1465-1478 | Published online: 12 Nov 2008

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Madia Lozupone, Francesco Panza, Eleonora Stella, Maddalena La Montagna, Paola Bisceglia, Giuseppe Miscio, Ilaria Galizia, Antonio Daniele, Lazzaro di Mauro, Antonello Bellomo, Giancarlo Logroscino, Antonio Greco & Davide Seripa. (2017) Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?. Expert Opinion on Drug Metabolism & Toxicology 13:3, pages 259-277.
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Articles from other publishers (21)

Parnika Prashasti Saxena. (2022) Commentary on ‘Perspectives on the Clinical Use of Pharmacogenetic Testing in Late-Life Mental Healthcare: A Survey of the American Association of Geriatric Psychiatry Membership’. The American Journal of Geriatric Psychiatry 30:5, pages 572-574.
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Donald D Chang, Harris A Eyre, Ryan Abbott, Michael Coudreaut, Bernhard T Baune, Jeffrey A Shaman, Helen Lavretsky, Eric J Lenze, David A Merrill, Ajeet B Singh, Benoit H Mulsant, Charles F ReynoldsIIIIII, Daniel J Müller & Chad Bousman. (2018) Pharmacogenetic guidelines and decision support tools for depression treatment: application to late-life. Pharmacogenomics 19:16, pages 1269-1284.
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Miriam Saiz-Rodríguez, Carmen Belmonte, Manuel Román, Dolores Ochoa, Dora Koller, María Talegón, María C. Ovejero-Benito, Rosario López-Rodríguez, Teresa Cabaleiro & Francisco Abad-Santos. (2018) Effect of Polymorphisms on the Pharmacokinetics, Pharmacodynamics and Safety of Sertraline in Healthy Volunteers. Basic & Clinical Pharmacology & Toxicology 122:5, pages 501-511.
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Lidan Dong, Ling Xu, Yanfei Li, Yinghua Lv, Hongxia Liu, Yunfei Li, Fengyan Xu, Junyi Wu, Qingshan Zheng & Lujin Li. (2018) Model-based comparing efficacy of fluoxetine between elderly and non-elderly participants with major depressive disorder. Journal of Affective Disorders 229, pages 224-230.
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Christopher F. Sharpley, David R.H. Christie, Vicki Bitsika, Nicholas M. Andronicos, Linda L. Agnew & Mary E. McMillan. (2017) Does psychological resilience buffer against the link between the 5-HTTLPR polymorphism and depression following stress. Physiology & Behavior 180, pages 53-59.
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Davide Seripa, Andrea Pilotto, Giulia Paroni, Andrea Fontana, Grazia D’Onofrio, Carolina Gravina, Maria Urbano, Leandro Cascavilla, Francesco Paris, Francesco Panza, Alessandro Padovani & Alberto Pilotto. (2015) Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life. Journal of Psychopharmacology 29:5, pages 623-633.
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Jeff S. Kruk, Maryam S. Vasefi, Nyasha Gondora, Nawaz Ahmed, John J. Heikkila & Michael A. Beazely. (2015) Fluoxetine-induced transactivation of the platelet-derived growth factor type β receptor reveals a novel heterologous desensitization process. Molecular and Cellular Neuroscience 65, pages 45-51.
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Paulo R. Shiroma, Maureen S. Drews, Jennifer R. Geske & David A. Mrazek. (2014) SLC6A4 Polymorphisms and Age of Onset in Late-life Depression on Treatment Outcomes with Citalopram: A Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Report. The American Journal of Geriatric Psychiatry 22:11, pages 1140-1148.
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A. Sicras-Mainar, P. Guijarro, B. Armada, M. Blanca-Tamayo & R. Navarro-Artieda. (2020) Influence of combinations of drugs that act on the CYP2D6 metabolic pathway in the treatment of major depressive disorder: A population-based study. European Psychiatry 29:6, pages 331-337.
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P Scibona, F Angriman, C Vazquez, BL Ferreyro, AG Perelsztein, VA Simonovich, JR Jauregui, CG Musso & WH Belloso. (2014) Individualization of drug therapy in older people. Reviews in Clinical Gerontology 24:2, pages 145-157.
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Christina Pataky-Forsyth, Philip Gerretsen & Bruce Pollock. 2014. Handbook of Personalized Medicine. Handbook of Personalized Medicine 341 374 .
Davide Seripa, Francesco Panza, Grazia D'Onofrio, Giulia Paroni, Alessandra Bizzarro, Andrea Fontana, Francesco Paris, Leandro Cascavilla, Massimiliano Copetti, Carlo Masullo & Alberto Pilotto. (2013) The Serotonin Transporter Gene Locus in Late-Life Major Depressive Disorder. The American Journal of Geriatric Psychiatry 21:1, pages 67-77.
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Carmen Andreescu & Charles F. Reynolds. (2012) Depresión a una edad avanzada: tratamiento basado en la evidencia y nuevos caminos prometedores para la investigación y la práctica clínica. Psiquiatría Biológica 19:4, pages 116-126.
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Sharon L. Naismith, Louisa M. Norrie, Loren Mowszowski & Ian B. Hickie. (2012) The neurobiology of depression in later-life: Clinical, neuropsychological, neuroimaging and pathophysiological features. Progress in Neurobiology 98:1, pages 99-143.
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Daniela Haeusler, Markus Mitterhauser & Wolfgang Wadsak. 2012. Radiochemical Syntheses. Radiochemical Syntheses 285 296 .
H P Rang, M M Dale, J M Ritter, R J Flower & G Henderson. 2012. Rang &amp Dale's Pharmacology. Rang &amp Dale's Pharmacology 564 583 .
Maurizio Cardelli, Francesca Marchegiani, Andrea Corsonello, Fabrizia Lattanzio & Mauro Provinciali. (2013) A Review of Pharmacogenetics of Adverse Drug Reactions in Elderly People. Drug Safety 35:S1, pages 3-20.
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Carmen Andreescu & Charles F. ReynoldsIIIIII. (2011) Late-life Depression: Evidence-based Treatment and Promising New Directions for Research and Clinical Practice. Psychiatric Clinics of North America 34:2, pages 335-355.
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Francisco J. de Abajo. (2011) Effects of Selective Serotonin Reuptake Inhibitors on Platelet Function. Drugs & Aging 28:5, pages 345-367.
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Richard Levy. (2010) Medication use by ethnic and racial groups: policy implications. Journal of Pharmaceutical Health Services Research 1:1, pages 15-22.
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Olga O. Yevtushenko & Gavin P. Reynolds. 2010. Handbook of the Behavioral Neurobiology of Serotonin. Handbook of the Behavioral Neurobiology of Serotonin 791 806 .

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