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Genomic and proteomic approaches for predicting toxicity and adverse drug reactions

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Pages 29-37 | Published online: 23 Dec 2008

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Articles from other publishers (16)

Young Hee Choi, Chang Yeob Han, Kwi Suk Kim & Sang Geon Kim. (2019) Future Directions of Pharmacovigilance Studies Using Electronic Medical Recording and Human Genetic Databases. Toxicological Research 35:4, pages 319-330.
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Leonardo Campos Zanelatto, Patrícia Benites Gonçalves da Silva, Daniele Sartori, Carolina Panis, Sandra Lepri, Ângelo de Fátima & Mário Sérgio Mantovani. (2016) LNO3 AND L3 Are Associated With Antiproliferative And Pro-Apoptotic Action In Hepatoma Cells. Genetics and Molecular Biology 39:2, pages 270-278.
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Hong W. Yu & William C. Cho. (2015) The role of microRNAs in toxicology. Archives of Toxicology 89:3, pages 319-325.
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Adrian Roth & Thomas Singer. (2014) The application of 3D cell models to support drug safety assessment: Opportunities & challenges. Advanced Drug Delivery Reviews 69-70, pages 179-189.
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Travis T. Wager, Bethany L. Kormos, Joseph T. Brady, Yvonne Will, Michael D. Aleo, Donald B. Stedman, Max Kuhn & Ramalakshmi Y. Chandrasekaran. (2013) Improving the Odds of Success in Drug Discovery: Choosing the Best Compounds for in Vivo Toxicology Studies. Journal of Medicinal Chemistry 56:23, pages 9771-9779.
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Yoko Nishimura, Yuji Morikawa, Chiaki Kondo, Yutaka Tonomura, Ryou Fukushima, Mikinori Torii & Takeki Uehara. (2013) Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies. Journal of Applied Toxicology 33:10, pages 1120-1130.
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Pritam Sahota, James Popp, Jerry Hardisty & Chirukandath GopinathMark Hoenerhoff & David Malarkey. 2013. Toxicologic Pathology. Toxicologic Pathology 175 208 .
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Patrick Y. Muller & Mark N. Milton. (2012) The determination and interpretation of the therapeutic index in drug development. Nature Reviews Drug Discovery 11:10, pages 751-761.
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Min Zhang, Minjun Chen & Weida Tong. (2011) Is Toxicogenomics a More Reliable and Sensitive Biomarker than Conventional Indicators from Rats To Predict Drug-Induced Liver Injury in Humans?. Chemical Research in Toxicology 25:1, pages 122-129.
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Margaret Barh, Debmalya Blum & Kenneth MadiganNalini Raghavachari. 2011. OMICS. OMICS 1 20 .
Daniel KrewskiMargit WestphalMustafa Al-ZoughoolMaxine C. CroteauMelvin E. Andersen. (2011) New Directions in Toxicity Testing. Annual Review of Public Health 32:1, pages 161-178.
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Shashi Amur, Issam Zineh, Darrell R Abernethy, Shiew-Mei Huang & Lawrence J Lesko. (2010) Pharmacogenomics and adverse drug reactions. Personalized Medicine 7:6, pages 633-642.
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Gopabandhu JenaAjit Vikram, Durga Nand Tripathi & Poduri Ramarao. (2010) Use of Chemoprotectants in Chemotherapy and Radiation Therapy: The Challenges of Selecting an Appropriate Agent. Integrative Cancer Therapies 9:3, pages 253-258.
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Yoko Mori, Chiaki Kondo, Yutaka Tonomura, Mikinori Torii & Takeki Uehara. (2010) Identification of potential genomic biomarkers for early detection of chemically induced cardiotoxicity in rats. Toxicology 271:1-2, pages 36-44.
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Mayukh Banerjee & Ashok K. Giri. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.

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