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Oral antidiabetic drug metabolism: pharmacogenomics and drug interactions

, MD &
Pages 225-241 | Published online: 16 Apr 2009

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Chunlan Zheng, Xiufen Hu, Li Zhao, Minhui Hu & Feng Gao. (2017) Clinical and pharmacological hallmarks of rifapentine’s use in diabetes patients with active and latent tuberculosis: do we know enough?. Drug Design, Development and Therapy 11, pages 2957-2968.
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Minhui Hu, Chunlan Zheng & Feng Gao. (2016) Use of bedaquiline and delamanid in diabetes patients: clinical and pharmacological considerations. Drug Design, Development and Therapy 10, pages 3983-3994.
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Andreas Holstein, Winfried Beil & Peter Kovacs. (2012) CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects. Expert Opinion on Drug Metabolism & Toxicology 8:12, pages 1549-1563.
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Jeffrey S Freeman & Benjamin Gross. (2012) Potential drug interactions associated with treatments for Type 2 diabetes and its comorbidities: a clinical pharmacology review. Expert Review of Clinical Pharmacology 5:1, pages 31-42.
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André J Scheen. (2011) Cytochrome P450-mediated cardiovascular drug interactions. Expert Opinion on Drug Metabolism & Toxicology 7:9, pages 1065-1082.
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Andreas Holstein, Claude Hammer, Michael Hahn, Nidhi-Su-Ann Kulamadayil & Peter Kovacs. (2010) Severe sulfonylurea-induced hypoglycemia: a problem of uncritical prescription and deficiencies of diabetes care in geriatric patients. Expert Opinion on Drug Safety 9:5, pages 675-681.
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Aikaterini Saiti, Alexandros Giannopoulos-Dimitriou, Ioannis Kazakos, Eleftheria Galatou & Ioannis S. Vizirianakis. (2023) Systems Pharmacology and Network Analysis to Advance Pharmacogenomics and Precision Medicine Decisions in Type-2 Diabetes Therapy. Future Pharmacology 3:1, pages 329-363.
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Elza Sundhani, Agung Endro Nugroho, Arief Nurrochmad, Ika Puspitasari, Dita Amalia Prihati & Endang Lukitaningsih. (2022) Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method. Molecules 27:20, pages 6901.
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Jia-Xu Li & Carolyn L. Cummins. (2022) Fresh insights into glucocorticoid-induced diabetes mellitus and new therapeutic directions. Nature Reviews Endocrinology 18:9, pages 540-557.
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Elza Sundhani, Endang Lukitaningsih, Arief Nurrochmad & Agung Endro Nugroho. (2022) Potential pharmacokinetic and pharmacodynamic herb-drug interactions of Andrographis paniculata (Burm. f.) and andrographolide: A systematic review. Journal of Herbmed Pharmacology 11:2, pages 154-165.
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Guyi Wang, Bing Xiao, Jiayi Deng, Linmei Gong, Yi Li, Jinxiu Li & Yanjun Zhong. (2022) The Role of Cytochrome P450 Enzymes in COVID-19 Pathogenesis and Therapy. Frontiers in Pharmacology 13.
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Catarina Andrade, Nelson G.M. Gomes, Sutsawat Duangsrisai, Paula B. Andrade, David M. Pereira & Patrícia Valentão. (2020) Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicals. Journal of Ethnopharmacology 263, pages 113177.
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Tapan Kumar Giri, Payel Roy & Subhasis Maity. (2020) Formulation and Characterization of Solid Dispersion Containing Capsaicin for the Treatment of Diabetes. Current Drug Therapy 15:3, pages 219-225.
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Derek LeRoith, Geert Jan Biessels, Susan S Braithwaite, Felipe F Casanueva, Boris Draznin, Jeffrey B Halter, Irl B Hirsch, Marie E McDonnell, Mark E Molitch, M Hassan Murad & Alan J Sinclair. (2019) Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism 104:5, pages 1520-1574.
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Susana Rivera-Mancía, Joyce Trujillo & José Pedraza Chaverri. (2018) Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies. Journal of Nutrition & Intermediary Metabolism 14, pages 29-41.
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Sarah Maximos, Michel Chamoun, Sophie Gravel, Jacques Turgeon & Veronique Michaud. (2017) Tissue Specific Modulation of cyp2c and cyp3a mRNA Levels and Activities by Diet-Induced Obesity in Mice: The Impact of Type 2 Diabetes on Drug Metabolizing Enzymes in Liver and Extra-Hepatic Tissues. Pharmaceutics 9:4, pages 40.
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X. Li & Z.Q. Liu. 2017. Drug Metabolism in Diseases. Drug Metabolism in Diseases 157 179 .
Amisha Wallia, Vidhya Illuri & Mark E. Molitch. (2016) Diabetes Care After Transplant. Medical Clinics of North America 100:3, pages 535-550.
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Yassine Réggami, Hajira Berredjem, Hadjer Cheloufi, Malika Berredjem & Noureddine Bouzerna. (2016) Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats. European Journal of Pharmacology 779, pages 122-130.
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Marcus May & Christoph Schindler. (2016) Clinically and pharmacologically relevant interactions of antidiabetic drugs. Therapeutic Advances in Endocrinology and Metabolism 7:2, pages 69-83.
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Allison J. Hahr & Mark E. Molitch. (2015) Management of diabetes mellitus in patients with chronic kidney disease. Clinical Diabetes and Endocrinology 1:1.
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Florence Ranchon, Thierry Vial, Catherine Rioufol, Emilie Hénin, Claire Falandry, Gilles Freyer, Véronique Trillet-Lenoir, Christophe Le Tourneau & Benoit You. (2015) Concomitant drugs with low risks of drug–drug interactions for use in oncology clinical trials. Critical Reviews in Oncology/Hematology 94:2, pages 189-200.
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Muhammad Amin & Naeti Suksomboon. (2014) Pharmacotherapy of Type 2 Diabetes Mellitus: An Update on Drug–Drug Interactions. Drug Safety 37:11, pages 903-919.
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Allison J. Hahr & Mark E. Molitch. 2014. Diabetes and Kidney Disease. Diabetes and Kidney Disease 205 214 .
Patricio Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes Georg Bode, Jennifer Bolleyn, Christoph Borner, Jan Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, María Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Chris E. P. Goldring, María José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann-Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens M. Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak-Ublick, Edward L. LeCluyse, Peng Lu, Jennifer Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz-Soja, Patrick McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nussler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan A. Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiss, Agata Widera, Courtney G. Woods, Jinghai James Xu, Kathy M. Yarborough & Jan G. Hengstler. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87:8, pages 1315-1530.
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Alexander Sämann & Ulrich A. Müller. 2013. Diabetes and Kidney Disease. Diabetes and Kidney Disease 186 201 .
Gaia Chiara Mannino & Giorgio Sesti. (2012) Individualized Therapy for Type 2 Diabetes. Molecular Diagnosis & Therapy 16:5, pages 285-302.
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Aleksi Tornio, Mikko Niemi, Pertti J. Neuvonen & Janne T. Backman. (2012) Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications. Trends in Pharmacological Sciences 33:6, pages 312-322.
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A. Holstein, Th. Duning, W. Kleophas, Ch. A. Schneider & Heinz-Jürgen Rüßmann. (2012) Wie kann dieser Notfall verhindert werden?. MMW - Fortschritte der Medizin 154:8, pages 62-69.
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Vita Dolžan. 2012. Pharmacogenetics and Individualized Therapy. Pharmacogenetics and Individualized Therapy 13 80 .
Lisa E. Hines & John E. Murphy. (2011) Potentially Harmful Drug–Drug Interactions in the Elderly: A Review. The American Journal of Geriatric Pharmacotherapy 9:6, pages 364-377.
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Hao Sun & Dennis O. Scott. (2011) Impact of genetic polymorphisms of cytochrome P450 2 C (CYP2C) enzymes on the drug metabolism and design of antidiabetics. Chemico-Biological Interactions 194:2-3, pages 159-167.
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F. Andreelli, D. Jacquier, A. Dierick-Gallet & C. Amouyal. (2011) Pharmacogénétique des antidiabétiques. Médecine des Maladies Métaboliques 5:5, pages 512-519.
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Vangelis G Manolopoulos, Georgia Ragia & Anna Tavridou. (2011) Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective. Pharmacogenomics 12:8, pages 1161-1191.
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A. Holstein. (2011) Impact of renal impairment on the risk of severe hypoglycaemia associated with the use of insulin and glyburide. Nephrology Dialysis Transplantation 26:5, pages 1748-1749.
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Andreas HolsteinAngela Seeringer & Peter Kovacs. (2011) Therapy with oral antidiabetic drugs: applied pharmacogenetics. The British Journal of Diabetes & Vascular Disease 11:1, pages 10-16.
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Jing Li, Martin H. Bluth & Andrea Ferreira-Gonzalez. 2011. Henry's Clinical Diagnosis and Management by Laboratory Methods. Henry's Clinical Diagnosis and Management by Laboratory Methods 1359 1382 .
André J. Scheen. (2010) Dipeptidylpeptitase-4 Inhibitors (Gliptins). Clinical Pharmacokinetics 49:9, pages 573-588.
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H Schelleman, W B Bilker, C M Brensinger, F Wan & S Hennessy. (2010) Anti-Infectives and the Risk of Severe Hypoglycemia in Users of Glipizide or Glyburide. Clinical Pharmacology & Therapeutics 88:2, pages 214-222.
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