Citations (179)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (20)
Isabella Damiani, Alberto Corsini & Stefano Bellosta. (2020) Potential statin drug interactions in elderly patients: a review. Expert Opinion on Drug Metabolism & Toxicology 16:12, pages 1133-1145.
Read now
Read now
Jiaqi Li, Liuying Di, Xu Cheng, Weiwen Ji, Hongyu Piao, Gang Cheng & Meijuan Zou. (2020) The characteristics and mechanism of co-administration of lovastatin solid dispersion with kaempferol to increase oral bioavailability. Xenobiotica 50:5, pages 593-601.
Read now
Read now
Stefano Bellosta & Alberto Corsini. (2018) Statin drug interactions and related adverse reactions: an update. Expert Opinion on Drug Safety 17:1, pages 25-37.
Read now
Read now
Xue-Feng Lu, Yang Zhou, Kai-Shun Bi & Xiao-Hui Chen. (2016) Mixed effects of OATP1B1, BCRP and NTCP polymorphisms on the population pharmacokinetics of pravastatin in healthy volunteers. Xenobiotica 46:9, pages 841-849.
Read now
Read now
Dewei Shang, Shuhua Deng, Zhenhong Yao, Zhanzhang Wang, Xiaojia Ni, Ming Zhang, Jinqing Hu, Haoyang Lu, Xiuqing Zhu, Wencan Huang, Chang Qiu & Yuguan Wen. (2016) The effect of food on the pharmacokinetic properties and bioequivalence of two formulations of pitavastatin calcium in healthy Chinese male subjects. Xenobiotica 46:1, pages 34-39.
Read now
Read now
Manuela de Lima Toccafondo Vieira & Carlos Alberto Tagliati. (2014) Hepatobiliary transporters in drug-induced cholestasis: a perspective on the current identifying tools. Expert Opinion on Drug Metabolism & Toxicology 10:4, pages 581-597.
Read now
Read now
Miao Hu & Brian Tomlinson. (2014) Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin. Expert Opinion on Drug Metabolism & Toxicology 10:1, pages 51-65.
Read now
Read now
Rebecca Schnepf & Oliver Zolk. (2013) Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications. Expert Opinion on Drug Metabolism & Toxicology 9:3, pages 287-306.
Read now
Read now
Stefano Bellosta & Alberto Corsini. (2012) Statin drug interactions and related adverse reactions. Expert Opinion on Drug Safety 11:6, pages 933-946.
Read now
Read now
Yurong Lai, Manthena Varma, Bo Feng, Joel Clay Stephens, Emi Kimoto, Ayman El-Kattan, Katsuomi Ichikawa, Hironori Kikkawa, Chiho Ono, Akiyuki Suzuki, Misaki Suzuki, Yuichi Yamamoto & Larry Tremaine. (2012) Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability – considerations for drug development. Expert Opinion on Drug Metabolism & Toxicology 8:6, pages 723-743.
Read now
Read now
Katherine S. Fenner, Hannah M. Jones, Mohammed Ullah, Sarah Kempshall, Maurice Dickins, Yurong Lai, Paul Morgan & Hugh A. Barton. (2012) The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance. Xenobiotica 42:1, pages 28-45.
Read now
Read now
Charles Harper & Terry Jacobson. (2011) Avoiding statin myopathy: understanding key drug interactions. Clinical Lipidology 6:6, pages 665-674.
Read now
Read now
Anna Koenen, Heyo K Kroemer, Markus Grube & Henriette E Meyer zu Schwabedissen. (2011) Current understanding of hepatic and intestinal OATP-mediated drug–drug interactions. Expert Review of Clinical Pharmacology 4:6, pages 729-742.
Read now
Read now
Grant T. Generaux, Fiorenza M. Bonomo, Marta Johnson & Kelly M. Mahar Doan. (2011) Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins. Xenobiotica 41:8, pages 639-651.
Read now
Read now
Alberto Corsini & Richard Ceska. (2011) Drug–drug interactions with statins: will pitavastatin overcome the statins’ Achilles’ heel?. Current Medical Research and Opinion 27:8, pages 1551-1562.
Read now
Read now
Bruno Stieger & Andreas Geier. (2011) Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis. Expert Opinion on Drug Metabolism & Toxicology 7:4, pages 411-425.
Read now
Read now
Erika K Pollex & Janine R Hutson. (2011) Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents. Expert Opinion on Drug Metabolism & Toxicology 7:3, pages 325-339.
Read now
Read now
Miao Hu, Kenneth KW To, Valiant WL Mak & Brian Tomlinson. (2011) The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins. Expert Opinion on Drug Metabolism & Toxicology 7:1, pages 49-62.
Read now
Read now
Christina Fahrmayr, Martin F. Fromm & Jörg König. (2010) Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects. Drug Metabolism Reviews 42:3, pages 380-401.
Read now
Read now
Masanori Horinouchi, Mariko Yagi, Hiroyuki Imanishi, Takeshi Mori, Tomoko Yanai, Akira Hayakawa, Yasuhiro Takeshima, Michiyo Hijioka, Noboru Okamura, Toshiyuki Sakaeda, Masafumi Matsuo, Katsuhiko Okumura & Tsutomu Nakamura. (2010) ASSOCIATION OF GENETIC POLYMORPHISMS WITH HEPATOTOXICITY IN PATIENTS WITH CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA OR LYMPHOMA. Pediatric Hematology and Oncology 27:5, pages 344-354.
Read now
Read now
Articles from other publishers (159)
Edward Zheng, Paulina Madura, Jakub Grandos, Marlena Broncel, Agnieszka Pawlos, Ewelina Woźniak & Paulina Gorzelak-Pabiś. (2024) When the same treatment has different response: The role of pharmacogenomics in statin therapy. Biomedicine & Pharmacotherapy 170, pages 115966.
Crossref
Crossref
Khurram Rehman, Zoya Iqbal, Deng Zhiqin, Hina Ayub, Naseem Saba, Muzammil Ahamd Khan, Liang Yujie & Li Duan. (2023) Analysis of genetic biomarkers, polymorphisms in ADME-related genes and their impact on pharmacotherapy for prostate cancer. Cancer Cell International 23:1.
Crossref
Crossref
Jessica Chu, Erika Panfen, Linna Wang, Anthony Marino, Xue-Qing Chen, R. Marcus Fancher, Raviraj Landage, Omprakash Patil, Salil Dileep Desai, Devang Shah, Yongjun Xue, Michael Sinz & Hong Shen. (2023) Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions. Pharmaceutical Research.
Crossref
Crossref
Terri L. Morton, Oscar L. Laskin, Diksha Kaushik, Lucy Lee, Jiyuan Ma, Allan Kristensen, Kylie O'Keefe, Lee Golden, Matthew Klein & Ronald Kong. (2023)
A pharmacokinetic drug–drug interaction study between rosuvastatin and emvododstat, a potent
anti‐SARS‐CoV
‐2 (
COVID
‐19)
DHODH
(dihydroorotate dehydrogenase) inhibitor
. Pharmacology Research & Perspectives 11:2.
Crossref
Crossref
Opeyemi Soremekun, Marie-Joe Dib, Skanda Rajasundaram, Segun Fatumo & Dipender Gill. (2023) Genetic heterogeneity in cardiovascular disease across ancestries: Insights for mechanisms and therapeutic intervention. Cambridge Prisms: Precision Medicine 1.
Crossref
Crossref
Parul Sharma, Navneet Singh & Siddharth Sharma. (2022)
Polymorphisms in solute carrier genes (
SLC19A1
,
SLCO1B1
, and
SLCO1B3
) predicts survival and toxicity in North Indian lung cancer patients undergoing platinum‐based doublet chemotherapy
. Journal of Clinical Pharmacy and Therapeutics 47:12, pages 2049-2067.
Crossref
Crossref
Gera Narendra, Shalki Choudhary, Baddipadige Raju, Himanshu Verma & Om Silakari. (2022) Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect. Clinical Pharmacokinetics 61:11, pages 1495-1517.
Crossref
Crossref
Mariana B. Morais & Mariana Verdelho Machado. (2022) Benign inheritable disorders of bilirubin metabolism manifested by conjugated hyperbilirubinemia–A narrative review. United European Gastroenterology Journal 10:7, pages 745-753.
Crossref
Crossref
Carlos Moctezuma-Velazquez & Juan Gonzalez Abraldes. (2022) The Role of Statins in Cirrhosis. Current Treatment Options in Gastroenterology 20:3, pages 316-335.
Crossref
Crossref
Vusumuzi N. Hove, Kenneth Anderson, Elizabeth R. Hayden, Kyle Z. Pasquariello, Alice A. Gibson, Shichen Shen, Jun Qu, Yan Jin, Jeffrey C. Miecznikowski, Shuiying Hu & Jason A. Sprowl. (2022) Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake. Molecular Pharmacology 101:6, pages 381-389.
Crossref
Crossref
Joo Young Na, Eunsol Yang, Jae‐Hoon Kim, In Sun Kwon, Eun‐Heui Jin, Kyung‐Sang Yu, Jinsook Kim, SeungHwan Lee & Jang Hee Hong. (2022) Comparative Pharmacokinetics Between a Fixed‐Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects. Clinical Pharmacology in Drug Development 11:5, pages 615-622.
Crossref
Crossref
Jinfu Peng, Guoping Yang & Zhijun Huang. (2022) Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs. Frontiers in Pharmacology 13.
Crossref
Crossref
Jiayi Ma, Karan Mathur, Jessica L. Muldoon, Marwan Ghabril, Naga Chalasani & Raj Vuppalanchi. (2022) Progressive Cholestasis and Biliary Cirrhosis After Initiating Oral Semaglutide: Report From the Drug-Induced Liver Injury Network. ACG Case Reports Journal 9:12, pages e00922.
Crossref
Crossref
Yoon-Jee Chae, Ji-Eun Chang, Mi-Kyung Lee, Juhee Lim, Kwang-Hee Shin & Kyeong-Ryoon Lee. (2021) Regulation of drug transporters by microRNA and implications in disease treatment. Journal of Pharmaceutical Investigation 52:1, pages 23-47.
Crossref
Crossref
Li Wang, Zhiyao Zhu, Doanh Tran, Shirley K. Seo & Xiaolei Pan. (2021) Advancing Estimation of Hepatobiliary Clearances in Physiologically Based Pharmacokinetic Models of Rosuvastatin Using Human Hepatic Concentrations. Pharmaceutical Research 38:12, pages 2035-2046.
Crossref
Crossref
Chen Ning, Shengdi Su, Jiaming Li, Dexuan Kong, Hui Cai, Zhiying Qin, Han Xing, Xijing Chen & Jiake He. (2021) Evaluation of a Clinically Relevant Drug–Drug Interaction Between Rosuvastatin and Clopidogrel and the Risk of Hepatotoxicity. Frontiers in Pharmacology 12.
Crossref
Crossref
Lemlem G Gebremichael, Vijayaprakash Suppiah, Michael D Wiese, Lorraine Mackenzie, Craig Phillips, Desmond B Williams & Michael S Roberts. (2021) Efficacy and safety of statins in ethnic differences: a lesson for application in Indigenous Australian patient care. Pharmacogenomics 22:9, pages 553-571.
Crossref
Crossref
Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa & Sanjeev Kumar. (2021) Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates. Drug Metabolism and Disposition 49:3, pages 254-264.
Crossref
Crossref
Ioannis Loisios-Konstantinidis & Jennifer Dressman. (2020)
Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Support Waivers of
In Vivo
Clinical Studies: Current Status, Challenges, and Opportunities
. Molecular Pharmaceutics 18:1, pages 1-17.
Crossref
Crossref
Ayaka Tajiri, Takeshi Hirota, Sasagu Kawano, Akira Yonamine & Ichiro Ieiri. (2020) Regulation of Organic Anion Transporting Polypeptide 2B1 Expression by MicroRNA in the Human Liver. Molecular Pharmaceutics 17:8, pages 2821-2830.
Crossref
Crossref
Azusa Kitao, Osamu Matsui, Norihide Yoneda, Kazuto Kozaka, Satoshi Kobayashi, Wataru Koda, Dai Inoue, Takahiro Ogi, Kotaro Yoshida & Toshifumi Gabata. (2020) Gadoxetic acid-enhanced MR imaging for hepatocellular carcinoma: molecular and genetic background. European Radiology 30:6, pages 3438-3447.
Crossref
Crossref
HariOm Singh, Sonam Lata, Ranjana Choudhari & Tapan N. Dhole. (2020)
Prevalence of
ABCC3
‐1767G/A polymorphism among patients with antiretroviral‐associated hepatotoxicity
. Molecular Genetics & Genomic Medicine 8:6.
Crossref
Crossref
Bodine P. S. Belderbos, Mirjam de With, Rajbir K. Singh, Bram C. Agema, Samira El Bouazzaoui, Esther Oomen-de Hoop, Ronald de Wit, Ron H. N. van Schaik, Ron H. J. Mathijssen & Sander Bins. (2020) The influence of single-nucleotide polymorphisms on overall survival and toxicity in cabazitaxel-treated patients with metastatic castration-resistant prostate cancer. Cancer Chemotherapy and Pharmacology 85:3, pages 547-553.
Crossref
Crossref
Ravindra Varma Alluri & Manthena V.S. Varma. 2020. Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters. Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters
609
631
.
Ting-Ting Li, Jia-Xing An, Jing-Yu Xu & Bi-Guang Tuo. (2019) Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver. World Journal of Clinical Cases 7:23, pages 3915-3933.
Crossref
Crossref
Sarah Billington, Steven Shoner, Scott Lee, Kindra Clark‐Snustad, Matthew Pennington, David Lewis, Mark Muzi, Shirley Rene, Jean Lee, Tot Bui Nguyen, Vineet Kumar, Kazuya Ishida, Laigao Chen, Xiaoyan Chu, Yurong Lai, Laurent Salphati, Cornelis E.C.A. Hop, Guangqing Xiao, Mingxiang Liao & Jashvant D. Unadkat. (2019)
Positron Emission Tomography Imaging of [
11
C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A
. Clinical Pharmacology & Therapeutics 106:5, pages 1056-1066.
Crossref
Crossref
Cindy Yanfei Li, Abdul Basit, Anshul Gupta, Zsuzsanna Gáborik, Emese Kis & Bhagwat Prasad. (2019) Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney. The Journal of Steroid Biochemistry and Molecular Biology 191, pages 105350.
Crossref
Crossref
Kenji Takahashi, Hiroshi Nakamura, Atsushi Watanabe, Tokifumi Majima, Masahito Koiwa, Toshikazu Kamada & Shinro Takai. (2019) Polymorphism in Organic Anion-Transporting Polypeptide Gene Related to Methotrexate Response in Rheumatoid Arthritis Treatment. Journal of Nippon Medical School 86:3, pages 149-158.
Crossref
Crossref
Rachael R. Schulte & Richard H. Ho. (2019) Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology. Molecular Pharmacology 95:5, pages 490-506.
Crossref
Crossref
Hidenori Kamio, Toshitaka Uchiyama, Hitoshi Kanno, Yoshiko Onoe, Kayoko Saito, Shingo Kameoka, Takako Kamio & Takahiro Okamoto. (2019)
Association between
SLCO1B1
rs4149056 and tegafur–uracil-induced hepatic dysfunction in breast cancer
. Pharmacogenomics 20:5, pages 353-365.
Crossref
Crossref
Daiki Mori, Yushi Kashihara, Takashi Yoshikado, Miyuki Kimura, Takeshi Hirota, Shunji Matsuki, Kazuya Maeda, Shin Irie, Ichiro Ieiri, Yuichi Sugiyama & Hiroyuki Kusuhara. (2019) Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers. Drug Metabolism and Pharmacokinetics 34:1, pages 78-86.
Crossref
Crossref
Elisa Pose, Jonel Trebicka, Rajeshwar P Mookerjee, Paolo Angeli & Pere Ginès. (2019) Statins: Old drugs as new therapy for liver diseases?. Journal of Hepatology 70:1, pages 194-202.
Crossref
Crossref
Akimitsu Maeda, Kei Irie, Hitoshi Ando, Ayako Hasegawa, Hiroya Taniguchi, Shigenori Kadowaki, Kei Muro, Masahiro Tajika, Masahiro Aoki, Kazuhide Inaguma, Masaki Kajita, Akio Fujimura & Shoji Fukushima. (2018) Associations among regorafenib concentrations, severe adverse reactions, and ABCG2 and OATP1B1 polymorphisms. Cancer Chemotherapy and Pharmacology 83:1, pages 107-113.
Crossref
Crossref
Yaru Xue, Chenhui Ma, Imad Hanna & Guoyu Pan. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity
361
405
.
Guoyu Pan. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity
293
340
.
Chamara Dalugama, Manoji Pathirage & S. A. M. Kularatne. (2018) Delayed presentation of severe rhabdomyolysis leading to acute kidney injury following atorvastatin-gemfibrozil combination therapy: a case report. Journal of Medical Case Reports 12:1.
Crossref
Crossref
Natalia Khuri & Shantanu Deshmukh. (2018) Machine Learning for Classification of Inhibitors of Hepatic Drug Transporters. Machine Learning for Classification of Inhibitors of Hepatic Drug Transporters.
Zsolt Sáfár, Márton Jani, Ildikó Makai, Zsolt Fekete, Annamária Bui, Éva Molnár, Petra Pádár, Jennifer R. Pratt, Emese Kis, Erzsébet Beéry & Péter Krajcsi. (2018) Correlation Analysis of Potential Breast Cancer Resistance Protein Probes in Different Monolayer Systems. Journal of Pharmaceutical Sciences 107:11, pages 2742-2747.
Crossref
Crossref
Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama & Yasuyoshi Watanabe. (2018)
A Clinical Quantitative Evaluation of Hepatobiliary Transport of [
11
C]Dehydropravastatin in Humans Using Positron Emission Tomography
. Drug Metabolism and Disposition 46:5, pages 719-728.
Crossref
Crossref
Ayman F. El-Kattan & Manthena V. S. Varma. (2018) Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System. Drug Metabolism and Disposition 46:5, pages 729-739.
Crossref
Crossref
Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi & Ichiro Ieiri. (2018) Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene. Drug Metabolism and Disposition 46:5, pages 628-635.
Crossref
Crossref
Rui Li & Hugh A. Barton. (2017) Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis. Clinical Pharmacokinetics 57:4, pages 491-503.
Crossref
Crossref
Deanna J. Brackman & Kathleen M. Giacomini. (2018)
Reverse Translational Research of
ABCG2
(BCRP) in Human Disease and Drug Response
. Clinical Pharmacology & Therapeutics 103:2, pages 233-242.
Crossref
Crossref
Soo Hyeon BaeWan-Su ParkSeunghoon HanGab-jin ParkJongtae LeeTaegon HongSangil JeonDong-Seok Yim. (2018) Physiologically-based pharmacokinetic predictions of intestinal BCRP-mediated drug interactions of rosuvastatin in Koreans. The Korean Journal of Physiology & Pharmacology 22:3, pages 321.
Crossref
Crossref
KP. Van Ness & EJ. Kelly. 2018. Comprehensive Toxicology. Comprehensive Toxicology
143
164
.
Darren Michael Moss, Marco Siccardi & Catia Marzolini. 2018. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions
49
85
.
Noriko Okudaira. (2017) Evaluation of New Chemical Entities as Substrates of Liver Transporters in the Pharmaceutical Industry: Response to Regulatory Requirements and Future Steps. Journal of Pharmaceutical Sciences 106:9, pages 2251-2256.
Crossref
Crossref
Issey Takehara, Hanano Terashima, Takeshi Nakayama, Takashi Yoshikado, Miwa Yoshida, Kenichi Furihata, Nobuaki Watanabe, Kazuya Maeda, Osamu Ando, Yuichi Sugiyama & Hiroyuki Kusuhara. (2017) Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers. Pharmaceutical Research 34:8, pages 1601-1614.
Crossref
Crossref
Yan Li, Jezrael Revalde & James W. Paxton. (2017) The effects of dietary and herbal phytochemicals on drug transporters. Advanced Drug Delivery Reviews 116, pages 45-62.
Crossref
Crossref
Soo Hyeon Bae, Wan-Su Park, Seunghoon Han, Gab-jin Park, Jongtae Lee, Taegon Hong, Sangil Jeon & Dong-Seok Yim. (2017) Retracted: Physiologically based pharmacokinetic predictions of intestinal BCRP-mediated effect of telmisartan on the pharmacokinetics of rosuvastatin in humans. Biopharmaceutics & Drug Disposition 38:5, pages 363-363.
Crossref
Crossref
Ayman F. El‐Kattan. 2017. Oral Bioavailability Assessment. Oral Bioavailability Assessment
309
329
.
Ayman F. El‐Kattan. 2017. Oral Bioavailability Assessment. Oral Bioavailability Assessment
203
267
.
Ayman F. El‐Kattan. 2017. Oral Bioavailability Assessment. Oral Bioavailability Assessment
387
430
.
T Prueksaritanont, DA Tatosian, X Chu, R Railkar, R Evers, C Chavez-Eng, R Lutz, W Zeng, J Yabut, GH Chan, X Cai, AH Latham, J Hehman, D Stypinski, J Brejda, C Zhou, B Thornton, KP Bateman, I Fraser & SA Stoch. (2017) Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A. Clinical Pharmacology & Therapeutics 101:4, pages 519-530.
Crossref
Crossref
Andrea Testa, Sergio Dall’Angelo, Marco Mingarelli, Andrea Augello, Lutz Schweiger, Andy Welch, Charles S. Elmore, Pradeep Sharma & Matteo Zanda. (2017) Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters. Bioorganic & Medicinal Chemistry 25:3, pages 963-976.
Crossref
Crossref
Elena Arrigoni, Marzia Del Re, Leonardo Fidilio, Stefano Fogli, Romano Danesi & Antonello Di Paolo. (2017) Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins. International Journal of Molecular Sciences 18:1, pages 104.
Crossref
Crossref
Guilian Zhao, Mei Liu, Xiujun Wu, Guofei Li, Feng Qiu, Jingkai Gu & Limei Zhao. (2017)
Effect of polymorphisms in
CYP3A4, PPARA, NR1I2, NFKB1, ABCG2
and
SLCO1B1
on the pharmacokinetics of lovastatin in healthy Chinese volunteers
. Pharmacogenomics 18:1, pages 65-75.
Crossref
Crossref
Masahiro Okada, Takamichi Murakami, Ryohei Kuwatsuru, Yuko Nakamura, Hiroyoshi Isoda, Satoshi Goshima, Ryota Hanaoka, Hiroki Haradome, Yoshinobu Shinagawa, Azusa Kitao, Yasunari Fujinaga, Nagaaki Marugami, Masako Yuki, Tomoaki Ichikawa, Atsushi Higaki, Masatoshi Hori, Shinya Fujii & Osamu Matsui. (2016) Biochemical and Clinical Predictive Approach and Time Point Analysis of Hepatobiliary Phase Liver Enhancement on Gd-EOB-DTPA–enhanced MR Images: A Multicenter Study. Radiology 281:2, pages 474-483.
Crossref
Crossref
T Yoshikado, K Yoshida, N Kotani, T Nakada, R Asaumi, K Toshimoto, K Maeda, H Kusuhara & Y Sugiyama. (2016) Quantitative Analyses of Hepatic OATP-Mediated Interactions Between Statins and Inhibitors Using PBPK Modeling With a Parameter Optimization Method. Clinical Pharmacology & Therapeutics 100:5, pages 513-523.
Crossref
Crossref
Sander Bins, Anne Lenting, Samira El Bouazzaoui, Leni van Doorn, Esther Oomen-de Hoop, Ferry ALM Eskens, Ron HN van Schaik & Ron HJ Mathijssen. (2016)
Polymorphisms in
SLCO1B1
and
UGT1A1
are associated with sorafenib-induced toxicity
. Pharmacogenomics 17:14, pages 1483-1490.
Crossref
Crossref
S. Ayalasomayajula, Y. Han, T. Langenickel, K. Malcolm, W. Zhou, I. Hanna, N. Alexander, A. Natrillo, B. Goswami, M. Hinder & G. Sunkara. (2016)
In vitro
and clinical evaluation of OATP-mediated drug interaction potential of sacubitril/valsartan (LCZ696)
. Journal of Clinical Pharmacy and Therapeutics 41:4, pages 424-431.
Crossref
Crossref
K. Kato, Y. Hasegawa, K. Iwata, T. Ichikawa, T. Yahara, S. Tsuji, M. Sugiura & J.-i. Yamaguchi. (2016) Recommendation to Exclude Bile-Duct-Cannulated Rats with Hyperbilirubinemia for Proper Conduct of Biliary Drug Excretion Studies. Drug Metabolism and Disposition 44:8, pages 1180-1183.
Crossref
Crossref
Tomoko Hasunuma, Masahiro Tohkin, Nahoko Kaniwa, In‐Jin Jang, Cui Yimin, Masaru Kaneko, Yoshiro Saito, Masahiro Takeuchi, Hiroshi Watanabe, Yasushi Yamazoe, Yoshiaki Uyama & Shinichi Kawai. (2016)
Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East
Asian
populations and Caucasians
. British Journal of Clinical Pharmacology 81:6, pages 1078-1090.
Crossref
Crossref
H. Shen, J. Dai, T. Liu, Y. Cheng, W. Chen, C. Freeden, Y. Zhang, W. G. Humphreys, P. Marathe & Y. Lai. (2016) Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species. Journal of Pharmacology and Experimental Therapeutics 357:2, pages 382-393.
Crossref
Crossref
Muzeeb Syed, Christian Skonberg & Steen Honoré Hansen. (2016) Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: Possible role in drug induced liver injury (DILI). Toxicology in Vitro 31, pages 93-102.
Crossref
Crossref
Li Wang, Yongchao Ren, Xugang shi, Dongya Yuan, Kai Liu, Tingting Geng, Gang Li, Longli Kang & Tian-bo Jin. (2016) The population genetics of pharmacogenomics VIP variants in the Sherpa population. Drug Metabolism and Pharmacokinetics 31:1, pages 82-89.
Crossref
Crossref
Tom De Bruyn, Bruno Stieger, Patrick F. Augustijns & Pieter P. Annaert. (2016) Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake. Journal of Pharmaceutical Sciences 105:2, pages 854-863.
Crossref
Crossref
Selvi Durmus, Gloria Lozano-Mena, Anita van Esch, Els Wagenaar, Olaf van Tellingen & Alfred H. Schinkel. (2015)
Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug–Drug Interactions
in Vivo
. Molecular Pharmaceutics 12:12, pages 4259-4269.
Crossref
Crossref
Manthena V. Varma, Stefanus J. Steyn, Charlotte Allerton & Ayman F. El-Kattan. (2015) Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS). Pharmaceutical Research 32:12, pages 3785-3802.
Crossref
Crossref
Shabnam Nazir, Zafar Iqbal, Yasar Shah, Lateef Ahmad & Abad Khan. (2014) Pharmacokinetic study of rosuvastatin in males and females. European Journal of Drug Metabolism and Pharmacokinetics 40:3, pages 313-318.
Crossref
Crossref
Yuta Tanaka, Yoshiaki Kitamura, Kazuya Maeda & Yuichi Sugiyama. (2015) Quantitative Analysis of the ABCG2 c.421C > A Polymorphism Effect on In Vivo Transport Activity of Breast Cancer Resistance Protein (BCRP) Using an Intestinal Absorption Model. Journal of Pharmaceutical Sciences 104:9, pages 3039-3048.
Crossref
Crossref
Manthena V. Varma, K. Sandy Pang, Nina Isoherranen & Ping Zhao. (2015) Dealing with the complex drug-drug interactions: Towards mechanistic models. Biopharmaceutics & Drug Disposition 36:2, pages 71-92.
Crossref
Crossref
Zidong Donna Fu, Julia Yue Cui & Curtis D. Klaassen. (2014) Atorvastatin induces bile acid-synthetic enzyme Cyp7a1 by suppressing FXR signaling in both liver and intestine in mice. Journal of Lipid Research 55:12, pages 2576-2586.
Crossref
Crossref
Carlos D. Malvestutto, Qing Ma, Gene D. Morse, James A. Underberg & Judith A. Aberg. (2014) Lack of Pharmacokinetic Interactions Between Pitavastatin and Efavirenz or Darunavir/Ritonavir. JAIDS Journal of Acquired Immune Deficiency Syndromes 67:4, pages 390-396.
Crossref
Crossref
K Yang, J L Woodhead, P B Watkins, B A Howell & K L R Brouwer. (2014) Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid–Mediated Troglitazone Hepatotoxicity. Clinical Pharmacology & Therapeutics 96:5, pages 589-598.
Crossref
Crossref
Manthena V. Varma, Yi-an Bi, Emi Kimoto & Jian Lin. (2014) Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model. Journal of Pharmacology and Experimental Therapeutics 351:1, pages 214-223.
Crossref
Crossref
Agnès Poirier, Renée Portmann, Anne-Christine Cascais, Urs Bader, Isabelle Walter, Mohammed Ullah & Christoph Funk. (2014) The Need for Human Breast Cancer Resistance Protein Substrate and Inhibition Evaluation in Drug Discovery and Development: Why, When, and How?. Drug Metabolism and Disposition 42:9, pages 1466-1477.
Crossref
Crossref
Thomayant Prueksaritanont, Xiaoyan Chu, Raymond Evers, Stephanie O. Klopfer, Luzelena Caro, Prajakti A. Kothare, Cynthia Dempsey, Scott Rasmussen, Robert Houle, Grace Chan, Xiaoxin Cai, Robert Valesky, Iain P. Fraser & S. Aubrey Stoch. (2014) Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin. British Journal of Clinical Pharmacology 78:3, pages 587-598.
Crossref
Crossref
Dan Xu, Feng Li, Mian Zhang, Ji Zhang, Can Liu, Meng-yue Hu, Ze-yu Zhong, Ling-ling Jia, Da-wei Wang, Jie Wu, Li Liu & Xiao-dong Liu. (2014) Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes. Acta Pharmacologica Sinica 35:9, pages 1215-1225.
Crossref
Crossref
Yu-hong Huang, Zi-qiang Li, Gui-xiang Pan, Yan-fen Li, Yu Liu, Jin-xia Sun, Xu-fang Gu, Na Li & Bao-he Wang. (2014) Comparison of Scaled-average, Population, and Individual Bioequivalence on 2 Tablets of Pitavastatin Calcium: A 3-Period, Reference-replicated, Crossover Study in Healthy Chinese Volunteers. Clinical Therapeutics 36:9, pages 1205-1216.e6.
Crossref
Crossref
Hiroyuki Kusuhara, Takashi Sekine, Naohiko Anzai & Hitoshi Endou. 2014. Drug Transporters. Drug Transporters
303
325
.
Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel & Nico Scheer. (2014) Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins. Drug Metabolism and Disposition 42:8, pages 1301-1313.
Crossref
Crossref
Rui Li, Hugh A. Barton & Manthena V. Varma. (2014) Prediction of Pharmacokinetics and Drug–Drug Interactions When Hepatic Transporters are Involved. Clinical Pharmacokinetics 53:8, pages 659-678.
Crossref
Crossref
. (2014) To avoid muscle-related adverse events, choose statins carefully in patients receiving antiviral protease inhibitors. Drugs & Therapy Perspectives 30:7, pages 264-267.
Crossref
Crossref
Márton Jani, Csilla Ambrus, Rémi Magnan, Katalin Tauberné Jakab, Erzsébet Beéry, Joseph K. Zolnerciks & Péter Krajcsi. (2014) Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics. Archives of Toxicology 88:6, pages 1205-1248.
Crossref
Crossref
Aizati NA Daud, Jorieke EH Bergman, Marian K Bakker, Hao Wang, Hermien EK de Walle, Torsten Plösch & Bob Wilffert. (2014) Pharmacogenetics of drug-induced birth defects: the role of polymorphisms of placental transporter proteins. Pharmacogenomics 15:7, pages 1029-1041.
Crossref
Crossref
Catherine M. Pastor, Beat Müllhaupt & Bruno Stieger. (2014) The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging. Drug Metabolism and Disposition 42:4, pages 675-684.
Crossref
Crossref
Beáta Tóth, Péter Krajcsi & Rémi Magnan. 2014. Biomarkers in Toxicology. Biomarkers in Toxicology
947
963
.
Tristan M. Sissung, Andrew K. L. Goey, Ariel M. Ley, Jonathan D. Strope & William D. Figg. 2014. Pharmacogenomics in Drug Discovery and Development. Pharmacogenomics in Drug Discovery and Development
91
120
.
Hironao Okubo, Hitoshi AndoShigehiro Kokubu, Akihisa Miyazaki, Sumio Watanabe & Akio Fujimura. (2013) Polymorphisms in the organic anion transporting polypeptide genes influence liver parenchymal enhancement in gadoxetic acid-enhanced MRI. Pharmacogenomics 14:13, pages 1573-1582.
Crossref
Crossref
Benoit Chauvin, Sylvain Drouot, Aurélie Barrail-Tran & Anne-Marie Taburet. (2013) Drug–Drug Interactions Between HMG-CoA Reductase Inhibitors (Statins) and Antiviral Protease Inhibitors. Clinical Pharmacokinetics 52:10, pages 815-831.
Crossref
Crossref
Yoshihisa Shitara, Kumiko Takeuchi & Toshiharu Horie. (2013) Long-Lasting Inhibitory Effects of Saquinavir and Ritonavir on OATP1B1-Mediated Uptake. Journal of Pharmaceutical Sciences 102:9, pages 3427-3435.
Crossref
Crossref
Patricio Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes Georg Bode, Jennifer Bolleyn, Christoph Borner, Jan Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, María Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Chris E. P. Goldring, María José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann-Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens M. Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak-Ublick, Edward L. LeCluyse, Peng Lu, Jennifer Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz-Soja, Patrick McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nussler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan A. Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiss, Agata Widera, Courtney G. Woods, Jinghai James Xu, Kathy M. Yarborough & Jan G. Hengstler. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87:8, pages 1315-1530.
Crossref
Crossref
ZongWen Wang, YingWei Fan, JinFa Chen, Ying Guo, WeiHua Wu, Ye He, LiangJun Xu & FengFu Fu. (2013) A microfluidic chip-based fluorescent biosensor for the sensitive and specific detection of label-free single-base mismatch via magnetic beads-based “sandwich” hybridization strategy. ELECTROPHORESIS 34:15, pages 2177-2184.
Crossref
Crossref
Daniel L Hertz. (2013) Germline pharmacogenetics of paclitaxel for cancer treatment. Pharmacogenomics 14:9, pages 1065-1084.
Crossref
Crossref
Brandon Swift, Noelia Nebot, Jin Kyung Lee, Tianxiang Han, William R. Proctor, Dhiren R. Thakker, Dieter Lang, Martin Radtke, Mark J. Gnoth & Kim L. R. Brouwer. (2013) Sorafenib Hepatobiliary Disposition: Mechanisms of Hepatic Uptake and Disposition of Generated Metabolites. Drug Metabolism and Disposition 41:6, pages 1179-1186.
Crossref
Crossref
J. H. Lewis & J. G. Stine. (2013) Review article: prescribing medications in patients with cirrhosis – a practical guide. Alimentary Pharmacology & Therapeutics 37:12, pages 1132-1156.
Crossref
Crossref
Lun Yang, Elvin T. Price, Ching-Wei Chang, Yan Li, Ying Huang, Li-Wu Guo, Yongli Guo, Jim Kaput, Leming Shi & Baitang Ning. (2013) Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters. PLoS ONE 8:4, pages e60368.
Crossref
Crossref
Jörg König & Martin F. Fromm. 2013. Pharmacogenomics of Human Drug Transporters. Pharmacogenomics of Human Drug Transporters
141
169
.
Li Li, Sagar Agarwal & William F. Elmquist. (2013) Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate. Drug Metabolism and Disposition 41:3, pages 659-667.
Crossref
Crossref
Douglas B. Kell, Paul D. Dobson, Elizabeth Bilsland & Stephen G. Oliver. (2013) The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so. Drug Discovery Today 18:5-6, pages 218-239.
Crossref
Crossref
Eun Sil Oh, Choon Ok Kim, Sung Kweon Cho, Min Soo Park & Jae-Yong Chung. (2013) Impact of ABCC2, ABCG2 and SLCO1B1 Polymorphisms on the Pharmacokinetics of Pitavastatin in Humans. Drug Metabolism and Pharmacokinetics 28:3, pages 196-202.
Crossref
Crossref
H.A. Chakkera, Y.-H. Chang, J.K. Bodner, S. Behmen, R.L. Heilman, K.S. Reddy, D.C. Mulligan, A.A. Moss, H. Khamash, N. Katariya, W.R. Hewitt, T.L. Pitta & L.A. Frassetto. (2013) Genetic Differences in Native Americans and Tacrolimus Dosing After Kidney Transplantation. Transplantation Proceedings 45:1, pages 137-141.
Crossref
Crossref
Bruno Stieger & Gerd A. Kullak-Ublick. 2013. Drug-Induced Liver Disease. Drug-Induced Liver Disease
123
133
.
Hiroyuki Kusuhara, Kenta Yoshida & Yuichi Sugiyama. 2013. Transporters in Drug Development. Transporters in Drug Development
67
97
.
Yoshihisa Shitara, Kazuya Maeda, Kazuaki Ikejiri, Kenta Yoshida, Toshiharu Horie & Yuichi Sugiyama. (2013) Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption. Biopharmaceutics & Drug Disposition 34:1, pages 45-78.
Crossref
Crossref
John Dickenson, Fiona Freeman, Chris Lloyd Mills, Shiva Sivasubramaniam & Christian Thode. 2012. Molecular Pharmacology. Molecular Pharmacology
201
226
.
Naoki Kotani, Kazuya Maeda, Yasuyuki Debori, Sandrine Camus, Ruoya Li, Christophe Chesne & Yuichi Sugiyama. (2012) Expression and Transport Function of Drug Uptake Transporters in Differentiated HepaRG Cells. Molecular Pharmaceutics 9:12, pages 3434-3441.
Crossref
Crossref
Alexander V. LyubimovKazuya Maeda & Yuichi Sugiyama. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
32
.
Yuko Sugita, Eisuke Inoue & Mamoru Narukawa. (2013) Impact of Clinical Response on Different Approved Doses in Japan and the United States. Clinical Pharmacology in Drug Development 1:4, pages 158-169.
Crossref
Crossref
Wen Jin Hua, Wei Xiao Hua & Hu Jin Fang. (2011) The Role of OATP1B1 and BCRP in Pharmacokinetics and DDI of Novel Statins. Cardiovascular Therapeutics 30:5.
Crossref
Crossref
Manthena V. S. Varma, Yurong Lai, Bo Feng, John Litchfield, Theunis C. Goosen & Arthur Bergman. (2012) Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions. Pharmaceutical Research 29:10, pages 2860-2873.
Crossref
Crossref
Karelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston & Aleksandra Galetin. (2012) Use of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat Hepatocytes. Drug Metabolism and Disposition 40:9, pages 1744-1756.
Crossref
Crossref
Choon O. Kim, Sung K. Cho, Eun S. Oh, Min S. Park & Jae-Yong Chung. (2012) Influence of ABCC2, SLCO1B1, and ABCG2 Polymorphisms on the Pharmacokinetics of Olmesartan. Journal of Cardiovascular Pharmacology 60:1, pages 49-54.
Crossref
Crossref
Kei Suzuki, Yoshihisa Shitara, Kousuke Fukuda & Toshiharu Horie. (2012) Long-Lasting Inhibition of the Intestinal Absorption of Fexofenadine by Cyclosporin a in Rats. Journal of Pharmaceutical Sciences 101:7, pages 2606-2615.
Crossref
Crossref
Miao Hu, Bernard M.Y. Cheung & Brian Tomlinson. (2012) Safety of statins: an update. Therapeutic Advances in Drug Safety 3:3, pages 133-144.
Crossref
Crossref
Ursula Ehmer, Sandra Kalthoff, Bastian Fakundiny, Brigitte Pabst, Nicole Freiberg, Ronald Naumann, Michael P. Manns & Christian P. Strassburg. (2012) Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation. Hepatology 55:6, pages 1912-1921.
Crossref
Crossref
Tadayuki Takashima, Satoshi Kitamura, Yasuhiro Wada, Masaaki Tanaka, Yoshihito Shigihara, Hideki Ishii, Ryosuke Ijuin, Susumu Shiomi, Takahiro Nakae, Yumiko Watanabe, Yilong Cui, Hisashi Doi, Masaaki Suzuki, Kazuya Maeda, Hiroyuki Kusuhara, Yuichi Sugiyama & Yasuyoshi Watanabe. (2012)
PET Imaging–Based Evaluation of Hepatobiliary Transport in Humans with (15
R
)-
11
C-TIC-Me
. Journal of Nuclear Medicine 53:5, pages 741-748.
Crossref
Crossref
Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai & Jashvant D. Unadkat. (2012) Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry. Drug Metabolism and Disposition 40:5, pages 852-855.
Crossref
Crossref
Lan-Xiang Wu, Cheng-Xian Guo, Wang-Qing Chen, Jing Yu, Qiang Qu, Yao Chen, Zhi-Rong Tan, Guo Wang, Lan Fan, Qing Li, Wei Zhang & Hong-Hao Zhou. (2012) Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment. British Journal of Clinical Pharmacology 73:5, pages 750-757.
Crossref
Crossref
Kuan Gandelman, Gordon L. Fung, Michael Messig & Rachel Laskey. (2012) Systemic Exposure to Atorvastatin Between Asian and Caucasian Subjects. American Journal of Therapeutics 19:3, pages 164-173.
Crossref
Crossref
Koji Kato, Hiroyuki Kusuhara, Yuji Kumagai, Ichiro Ieiri, Haruyuki Mori, Sumito Ito, Yasuhiro Nakai, Kazuya Maeda & Yuichi Sugiyama. (2012) Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in healthy Japanese individuals. Pharmacogenetics and Genomics 22:5, pages 344-354.
Crossref
Crossref
Imad Hanna & Ryan M. Pelis. 2012. ADME‐Enabling Technologies in Drug Design and Development. ADME‐Enabling Technologies in Drug Design and Development
29
54
.
Praveen V. Balimane, Yong‐Hae Han & Saeho Chong. 2012. ADME‐Enabling Technologies in Drug Design and Development. ADME‐Enabling Technologies in Drug Design and Development
161
168
.
Karelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston & Aleksandra Galetin. (2012) Simultaneous Assessment of Uptake and Metabolism in Rat Hepatocytes: A Comprehensive Mechanistic Model. Journal of Pharmacology and Experimental Therapeutics 341:1, pages 2-15.
Crossref
Crossref
Andrew A. Monte, Kennon J. Heard & Vasilis Vasiliou. (2011) Prediction of Drug Response and Safety in Clinical Practice. Journal of Medical Toxicology 8:1, pages 43-51.
Crossref
Crossref
Helen Graham, Mike Walker, Owen Jones, James Yates, Aleksandra Galetin & Leon Aarons. (2012) Comparison of in-vivo and in-silico methods used for prediction of tissue: plasma partition coefficients in rat. Journal of Pharmacy and Pharmacology 64:3, pages 383-396.
Crossref
Crossref
Dilek Iusuf, Evita van de Steeg & Alfred H. Schinkel. (2012) Functions of OATP1A and 1B transporters in vivo: insights from mouse models. Trends in Pharmacological Sciences 33:2, pages 100-108.
Crossref
Crossref
Ichiro Ieiri. (2012) Functional Significance of Genetic Polymorphisms in P-glycoprotein (MDR1, ABCB1) and Breast Cancer Resistance Protein (BCRP, ABCG2). Drug Metabolism and Pharmacokinetics 27:1, pages 85-105.
Crossref
Crossref
Yoshihisa Shitara, Kumiko Takeuchi, Yoshiko Nagamatsu, Satomi Wada, Yuichi Sugiyama & Toshiharu Horie. (2012) Long-lasting Inhibitory Effects of Cyclosporin A, but Not Tacrolimus, on OATP1B1- and OATP1B3-mediated Uptake. Drug Metabolism and Pharmacokinetics 27:4, pages 368-378.
Crossref
Crossref
J.P. Keogh. 2012. Current Concepts in Drug Metabolism and Toxicology. Current Concepts in Drug Metabolism and Toxicology
1
42
.
Alison J. Wilby, Kazuya Maeda, Paul F. Courtney, Yasuyuki Debori, Peter J. H. Webborn, Yoshiaki Kitamura, Hiroyuki Kusuhara, Rob J. Riley & Yuichi Sugiyama. (2011) Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4. Drug Metabolism and Disposition 39:12, pages 2361-2369.
Crossref
Crossref
Hiroshi TAKANE. (2011) Genetic Polymorphisms of <i>SLCO1B1</i> for Drug Pharmacokinetics and Its Clinical Implications薬物の体内動態に及ぼす<i>SLCO1B1</i>遺伝子多型の影響と臨床的意義. YAKUGAKU ZASSHI 131:11, pages 1589-1594.
Crossref
Crossref
Yoshiyuki Yabe, Aleksandra Galetin & J. Brian Houston. (2011) Kinetic Characterization of Rat Hepatic Uptake of 16 Actively Transported Drugs. Drug Metabolism and Disposition 39:10, pages 1808-1814.
Crossref
Crossref
Ryan M. Pelis & Stephen H. Wright. 2011. Comprehensive Physiology. Comprehensive Physiology
1795
1835
.
Alice C. Rodrigues, Paula M. S. Perin, Sheila G. Purim, Vivian N. Silbiger, Fabiana D. V. Genvigir, Maria Alice V. Willrich, Simone S. Arazi, Andre D. Luchessi, Mario H. Hirata, Marcia M. S. Bernik, Egidio L. Dorea, Carla Santos, Andre A. Faludi, Marcelo C. Bertolami, Antonio Salas, Ana Freire, Maria V. Lareu, Christopher Phillips, Liliana Porras-Hurtado, Manuel Fondevila, Angel Carracedo & Rosario D. C. Hirata. (2011) Pharmacogenetics of OATP Transporters Reveals That SLCO1B1 c.388A>G Variant Is Determinant of Increased Atorvastatin Response. International Journal of Molecular Sciences 12:9, pages 5815-5827.
Crossref
Crossref
Owen M. Woodward, Anna Köttgen & Michael Köttgen. (2011) ABCG transporters and disease. The FEBS Journal 278:18, pages 3215-3225.
Crossref
Crossref
Shigeki Sekine, Reiko Ogawa, Hidenori Ojima & Yae Kanai. (2011) Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma. Cancer Science 102:9, pages 1742-1747.
Crossref
Crossref
Akihiro Yamada, Kazuya Maeda, Naoki Ishiguro, Yasuhiro Tsuda, Takashi Igarashi, Thomas Ebner, Willy Roth, Shinichi Ikushiro & Yuichi Sugiyama. (2011) The impact of pharmacogenetics of metabolic enzymes and transporters on the pharmacokinetics of telmisartan in healthy volunteers. Pharmacogenetics and Genomics 21:9, pages 523-530.
Crossref
Crossref
Takashi Sekine & Hiroyuki Kusuhara. 2011. Oral Bioavailability. Oral Bioavailability
309
327
.
Maria L. H. Vlaming, Anita van Esch, Evita van de Steeg, Zeliha Pala, Els Wagenaar, Olaf van Tellingen & Alfred H. Schinkel. (2011) Impact of Abcc2 [Multidrug Resistance-Associated Protein (Mrp) 2], Abcc3 (Mrp3), and Abcg2 (Breast Cancer Resistance Protein) on the Oral Pharmacokinetics of Methotrexate and Its Main Metabolite 7-Hydroxymethotrexate. Drug Metabolism and Disposition 39:8, pages 1338-1344.
Crossref
Crossref
Ichiro Ieiri, Chisa Nishimura, Kazuya Maeda, Tomohiro Sasaki, Miyuki Kimura, Takeshi Chiyoda, Tekeshi Hirota, Shin Irie, Hitoshi Shimizu, Takanori Noguchi, Kenji Yoshida & Yuichi Sugiyama. (2011) Pharmacokinetic and pharmacogenomic profiles of telmisartan after the oral microdose and therapeutic dose. Pharmacogenetics and Genomics 21:8, pages 495-505.
Crossref
Crossref
Manthena V. Varma, Charles J. Rotter, Jonathan Chupka, Kevin M. Whalen, David B. Duignan, Bo Feng, John Litchfield, Theunis C. Goosen & Ayman F. El-Kattan. (2011) pH-Sensitive Interaction of HMG-CoA Reductase Inhibitors (Statins) with Organic Anion Transporting Polypeptide 2B1. Molecular Pharmaceutics 8:4, pages 1303-1313.
Crossref
Crossref
Jibin Li, Donna A. Volpe, Ying Wang, Wei Zhang, Chris Bode, Albert Owen & Ismael J. Hidalgo. (2011) Use of Transporter Knockdown Caco-2 Cells to Investigate the In Vitro Efflux of Statin Drugs. Drug Metabolism and Disposition 39:7, pages 1196-1202.
Crossref
Crossref
Kazuya Maeda & Yuichi Sugiyama. (2011) Novel strategies for microdose studies using non-radiolabeled compounds. Advanced Drug Delivery Reviews 63:7, pages 532-538.
Crossref
Crossref
Heather Pressler, Tristan M. Sissung, David Venzon, Douglas K. Price & William D. Figg. (2011) Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of Progression. PLoS ONE 6:5, pages e20372.
Crossref
Crossref
Bruno Stieger & Peter J Meier. (2011) Pharmacogenetics of drug transporters in the enterohepatic circulation. Pharmacogenomics 12:5, pages 611-631.
Crossref
Crossref
Masanori Ichikawa, Aki Yokomizo, Masao Itoh, Kazuyuki Sugita, Hiroyuki Usui, Hironari Shimizu, Makoto Suzuki, Koji Terayama & Akira Kanda. (2011) Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors. Bioorganic & Medicinal Chemistry 19:6, pages 1930-1949.
Crossref
Crossref
Yoshihisa Shitara. (2011) Clinical Importance of OATP1B1 and OATP1B3 in DrugDrug Interactions. Drug Metabolism and Pharmacokinetics 26:3, pages 220-227.
Crossref
Crossref
Catia Marzolini, Manuel Battegay & David Back. 2011. Drug Interactions in Infectious Diseases. Drug Interactions in Infectious Diseases
43
72
.
Iván L. Csanaky, Hong Lu, Youcai Zhang, Kenichiro Ogura, Supratim Choudhuri & Curtis D. Klaassen. (2011) Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice. Hepatology 53:1, pages 272-281.
Crossref
Crossref
Stephan Buch, Clemens Schafmayer, Henry Völzke, Marcus Seeger, Juan F. Miquel, Silvia C. Sookoian, Jan H. Egberts, Alexander Arlt, Carlos J. Pirola, Markus M. Lerch, Ulrich John, Andre Franke, Oliver von Kampen, Mario Brosch, Michael Nothnagel, Wolfgang Kratzer, Bernhard O. Boehm, Dieter C. Bröring, Stefan Schreiber, Michael Krawczak & Jochen Hampe. (2010) Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition. Gastroenterology 139:6, pages 1942-1951.e2.
Crossref
Crossref
Tae Kaneda, Shuichi Tsuruoka & Akio Fujimura. (2010) Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells. European Journal of Pharmacology 649:1-3, pages 38-43.
Crossref
Crossref
Takao Watanabe, Hiroyuki Kusuhara & Yuichi Sugiyama. (2010) Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans. Journal of Pharmacokinetics and Pharmacodynamics 37:6, pages 575-590.
Crossref
Crossref
Jane PF Bai. (2010) Drug delivery to the brain: considerations of genetic polymorphisms of blood–brain barrier transporters and imaging technologies. Therapeutic Delivery 1:4, pages 563-570.
Crossref
Crossref
Hajime Fukuda, Rikiya Ohashi, Noriko Ohashi, Hikaru Yabuuchi & Ikumi Tamai. (2010) Estimation of Transporters Involved in the Hepatobiliary Transport of TA-0201CA Using Sandwich-Cultured Rat Hepatocytes from Normal and Multidrug Resistance-Associated Protein 2-Deficient Rats. Drug Metabolism and Disposition 38:9, pages 1505-1513.
Crossref
Crossref
Kiyohiko Sugano, Manfred Kansy, Per Artursson, Alex Avdeef, Stefanie Bendels, Li Di, Gerhard F. Ecker, Bernard Faller, Holger Fischer, Grégori Gerebtzoff, Hans Lennernaes & Frank Senner. (2010) Coexistence of passive and carrier-mediated processes in drug transport. Nature Reviews Drug Discovery 9:8, pages 597-614.
Crossref
Crossref
S P R Romaine, K M Bailey, A S Hall & A J Balmforth. (2009) The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy. The Pharmacogenomics Journal 10:1, pages 1-11.
Crossref
Crossref
Aleksandra Galetin, Michael Gertz & J. Brian Houston. (2010) Contribution of Intestinal Cytochrome P450-Mediated Metabolism to Drug-Drug Inhibition and Induction Interactions. Drug Metabolism and Pharmacokinetics 25:1, pages 28-47.
Crossref
Crossref