Citations (49)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Mohammad Mahdi Vahedi, Davood Mahdian, Amir Hossein Jafarian, Mehrdad Iranshahi, Mahdi Esmaeilizadeh & Ahmad Ghorbani. (2018) Toxicity assessment of Ferula gummosa administration during pregnancy, lactation, and juvenile period in rat. Drug and Chemical Toxicology 41:2, pages 199-205.
Read now
Read now
Johnny X Huang, Mark A Blaskovich & Matthew A Cooper. (2014) Cell- and biomarker-based assays for predicting nephrotoxicity. Expert Opinion on Drug Metabolism & Toxicology 10:12, pages 1621-1635.
Read now
Read now
Sarah Campion, Jiri Aubrecht, Kim Boekelheide, David W Brewster, Vishal S Vaidya, Linnea Anderson, Deborah Burt, Edward Dere, Kathleen Hwang, Sara Pacheco, Janani Saikumar, Shelli Schomaker, Mark Sigman & Federico Goodsaid. (2013) The current status of biomarkers for predicting toxicity. Expert Opinion on Drug Metabolism & Toxicology 9:11, pages 1391-1408.
Read now
Read now
Marcela
Rodrigues De Camargo, Luís
Fernando Barbisan, Meire
França Martinez, Carla
Adriene Da Silva Franchi, João
Lauro Viana De Camargo & Ana
Lúcia Tozzi Spinardi-Barbisan. (2013) Macrophage activity and histopathology of the lymphohematopoietic organs in male Wistar rats orally exposed to single or mixed pesticides. Journal of Environmental Science and Health, Part B 48:7, pages 607-613.
Read now
Read now
Jonathan Moggs, Pierre Moulin, Francois Pognan, Dominique Brees, Michele Leonard, Steve Busch, Andre Cordier, David J Heard, Michael Kammüller, Michael Merz, Page Bouchard & Salah-Dine Chibout. (2012) Investigative safety science as a competitive advantage for Pharma. Expert Opinion on Drug Metabolism & Toxicology 8:9, pages 1071-1082.
Read now
Read now
Icilio Cavero. (2012) 2011 Annual Meeting of the Safety Pharmacology Society: an overview. Expert Opinion on Drug Safety 11:2, pages 341-353.
Read now
Read now
Uwe Christians, Jost Klawitter, Jelena Klawitter, Nina Brunner & Volker Schmitz. (2011) Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions. Expert Opinion on Drug Metabolism & Toxicology 7:2, pages 175-200.
Read now
Read now
Gordon Liss, Sushil Rattan & James H Lewis. (2010) Predicting and preventing acute drug-induced liver injury: what's new in 2010?. Expert Opinion on Drug Metabolism & Toxicology 6:9, pages 1047-1061.
Read now
Read now
Elizabeth A Tengstrand, Gerald T Miwa & Frank Y Hsieh. (2010) Bis(monoacylglycerol)phosphate as a non-invasive biomarker to monitor the onset and time-course of phospholipidosis with drug-induced toxicities. Expert Opinion on Drug Metabolism & Toxicology 6:5, pages 555-570.
Read now
Read now
Articles from other publishers (40)
Andra-Sorina Tatar, Cosmin Farcău, Adriana Vulpoi, Sanda Boca & Simion Astilean. (2022) Development and evaluation of a gold nanourchin (GNU)-based sandwich architecture for SERS immunosensing in liquid. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 273, pages 121069.
Crossref
Crossref
Robert N. Schuck, Jana G. Delfino, Christopher Leptak & John A. Wagner. 2022. Atkinson's Principles of Clinical Pharmacology. Atkinson's Principles of Clinical Pharmacology
323
342
.
Anne Rix, Natascha Ingrid Drude, Anna Mrugalla, Ferhan Baskaya, Koon Yan Pak, Brian Gray, Hans-Jürgen Kaiser, René Hany Tolba, Eva Fiegle, Wiltrud Lederle, Felix Manuel Mottaghy & Fabian Kiessling. (2019) Assessment of Chemotherapy-Induced Organ Damage with Ga-68 Labeled Duramycin. Molecular Imaging and Biology 22:3, pages 623-633.
Crossref
Crossref
Alexandre J. S. Ribeiro, Xinning Yang, Vikram Patel, Rajnikanth Madabushi & David G. Strauss. (2019) Liver Microphysiological Systems for Predicting and Evaluating Drug Effects. Clinical Pharmacology & Therapeutics 106:1, pages 139-147.
Crossref
Crossref
Xiao xu Li, Jiayi Yin, Jing Tang, Yinghong Li, Qingxia Yang, Ziyu Xiao, Runyuan Zhang, Yunxia Wang, Jiajun Hong, Lin Tao, Weiwei Xue & Feng Zhu. (2018) Determining the Balance Between Drug Efficacy and Safety by the Network and Biological System Profile of Its Therapeutic Target. Frontiers in Pharmacology 9.
Crossref
Crossref
Marcela Rodrigues de Camargo, Pedro Vinicius Teruya Akamine, James Venturini, Maria Sueli P. de Arruda & Carla Adriene da Silva Franchi. (2017) Pesticide dichorvos induces early solid Ehrlich tumoral development associated with a non-protective pro-inflammatory response. Environmental Science and Pollution Research 25:8, pages 7681-7687.
Crossref
Crossref
Ermei Chen, Juan Lu, Deying Chen, Danhua Zhu, Yini Wang, Yimin Zhang, Ning Zhou, Jie Wang, Jianzhou Li & Lanjuan Li. (2017) Dynamic changes of plasma metabolites in pigs with GalN-induced acute liver failure using GC–MS and UPLC–MS. Biomedicine & Pharmacotherapy 93, pages 480-489.
Crossref
Crossref
William R. Proctor, Alison J. Foster, Jennifer Vogt, Claire Summers, Brian Middleton, Mark A. Pilling, Daniel Shienson, Monika Kijanska, Simon Ströbel, Jens M. Kelm, Paul Morgan, Simon Messner & Dominic Williams. (2017) Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury. Archives of Toxicology 91:8, pages 2849-2863.
Crossref
Crossref
U. Christians, J. Klawitter, J. Klepacki & J. Klawitter. 2017. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease
119
223
.
U. Christians, J. Klawitter, J. Klepacki & J. Klawitter. 2017. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease
33
118
.
Aaron Smith, John Calley, Sachin Mathur, Hui-Rong Qian, Han Wu, Mark Farmen, Florian Caiment, Pierre R. Bushel, Jianying Li, Craig Fisher, Patrick Kirby, Erik Koenig, David G. Hall & David E Watson. (2016) The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog. BMC Genomics 17:1.
Crossref
Crossref
Ahmad Ghorbani, Reza Mohebbati, Amir Hossein Jafarian, Mohammad Mahdi Vahedi, Seyed Mahmoud Hosseini, Mohammad Soukhtanloo, Hamid Reza Sadeghnia & Azar hosseini. (2016) Toxicity evaluation of hydroalcoholic extract of Ferula gummosa root. Regulatory Toxicology and Pharmacology 77, pages 35-41.
Crossref
Crossref
G Lavezzari & AW Womack. (2015) Industry perspectives on biomarker qualification. Clinical Pharmacology & Therapeutics 99:2, pages 208-213.
Crossref
Crossref
Xuemei Zhao, Vijay Modur, Leonidas N Carayannopoulos & Omar F Laterza. (2015) Biomarkers in Pharmaceutical Research. Clinical Chemistry 61:11, pages 1343-1353.
Crossref
Crossref
Richard D. Beger, Sudeepa Bhattacharyya, Xi Yang, Pritmohinder S. Gill, Laura K. Schnackenberg, Jinchun Sun & Laura P. James. (2015) Translational biomarkers of acetaminophen-induced acute liver injury. Archives of Toxicology 89:9, pages 1497-1522.
Crossref
Crossref
Fangping Liu, Yuexia Lin, Zhi Li, Xin Ma, Qing Han, Yingshu Liu, Qiong Zhou, Jingli Liu, Rui Li, Jichang Li & Li Gao. (2014) Glutathione S-transferase A1 (GSTA1) release, an early indicator of acute hepatic injury in mice. Food and Chemical Toxicology 71, pages 225-230.
Crossref
Crossref
Mira Pavkovic, Björn Riefke, Katrin Gutberlet, Marian Raschke & Heidrun Ellinger-Ziegelbauer. (2014) Comparison of the Mesoscale Discovery and Luminex multiplex platforms for measurement of urinary biomarkers in a cisplatin rat kidney injury model. Journal of Pharmacological and Toxicological Methods 69:2, pages 196-204.
Crossref
Crossref
Junnat Hamdam, Swaminathan Sethu, Trevor Smith, Ana Alfirevic, Mohammad Alhaidari, Jeffrey Atkinson, Mimieveshiofuo Ayala, Helen Box, Michael Cross, Annie Delaunois, Ailsa Dermody, Karthik Govindappa, Jean-Michel Guillon, Rosalind Jenkins, Gerry Kenna, Björn Lemmer, Ken Meecham, Adedamola Olayanju, Sabine Pestel, Andreas Rothfuss, James Sidaway, Rowena Sison-Young, Emma Smith, Richard Stebbings, Yulia Tingle, Jean-Pierre Valentin, Awel Williams, Dominic Williams, Kevin Park & Christopher Goldring. (2013) Safety pharmacology — Current and emerging concepts. Toxicology and Applied Pharmacology 273:2, pages 229-241.
Crossref
Crossref
Rahul Bohra, Jacek Klepacki, Jelena Klawitter, Jost Klawitter, Joshua M. Thurman & Uwe Christians. (2013) Proteomics and metabolomics in renal transplantation-quo vadis?. Transplant International 26:3, pages 225-241.
Crossref
Crossref
Shingo Okubo, Makoto Miyamoto, Kenji Takami, Masayuki Kanki, Atsushi Ono, Noriyuki Nakatsu, Hiroshi Yamada, Yasuo Ohno & Tetsuro Urushidani. (2013) Identification of Novel Liver-Specific mRNAs in Plasma for Biomarkers of Drug-Induced Liver Injury and Quantitative Evaluation in Rats Treated With Various Hepatotoxic Compounds. Toxicological Sciences 132:1, pages 21-31.
Crossref
Crossref
Ibon Iloro, Esperanza Gonzalez, Virginia Gutierrez-de Juan, Jose M. Mato, Juan M. Falcon-Perez & Felix Elortza. (2013) Non-invasive detection of drug toxicity in rats by solid-phase extraction and MALDI-TOF analysis of urine samples. Analytical and Bioanalytical Chemistry 405:7, pages 2311-2320.
Crossref
Crossref
W. B. Mattes, H. G. Kamp, E. Fabian, M. Herold, G. Krennrich, R. Looser, W. Mellert, A. Prokoudine, V. Strauss, B. van Ravenzwaay, T. Walk, H. Naraoka, K. Omura, I. Schuppe-Koistinen, S. Nadanaciva, E. D. Bush, N. Moeller, P. Ruiz-Noppinger & S. P. Piccoli. (2013) Prediction of Clinically Relevant Safety Signals of Nephrotoxicity through Plasma Metabolite Profiling. BioMed Research International 2013, pages 1-12.
Crossref
Crossref
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson & Jean-Pierre Valentin. (2013) Functional assessments in repeat-dose toxicity studies: the art of the possible. Toxicology Research 2:4, pages 209.
Crossref
Crossref
Graham S. Smith, Gail L. Walter & Robin M. Walker. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology
565
594
.
Myrtle A. Davis, Sandy Eldridge & Calvert Louden. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology
317
352
.
Jürgen Sandow. 2013. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
421
520
.
Bruce Campbell & Bob Ings. 2013. Global Approach in Safety Testing. Global Approach in Safety Testing
119
158
.
Esperanza Gonzalez, Sebastiaan van Liempd, Javier Conde-Vancells, Virginia Gutierrez-de Juan, Miriam Perez-Cormenzana, Rebeca Mayo, Agustin Berisa, Cristina Alonso, Cesar A. Marquez, Jonathan Barr, Shelly C. Lu, Jose M. Mato & Juan M. Falcon-Perez. (2011) Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity. Metabolomics 8:6, pages 997-1011.
Crossref
Crossref
Uwe Christians, Jacek Klepacki, Touraj Shokati, Jost Klawitter & Jelena Klawitter. (2012) Mass spectrometry-based multiplexing for the analysis of biomarkers in drug development and clinical diagnostics — How much is too much?. Microchemical Journal 105, pages 32-38.
Crossref
Crossref
Nicola M Robas. (2012) Use of PD biomarkers to drive dose selection and early clinical decision making. Bioanalysis 4:20, pages 2485-2497.
Crossref
Crossref
Patrick Y. Muller & Mark N. Milton. (2012) The determination and interpretation of the therapeutic index in drug development. Nature Reviews Drug Discovery 11:10, pages 751-761.
Crossref
Crossref
Uwe Christians, Volker Schmitz, Jost Klawitter & Jelena Klawitter. 2012. Analytical Techniques for Clinical Chemistry. Analytical Techniques for Clinical Chemistry
691
774
.
Tewes Tralau & Andreas Luch. (2012) Drug-mediated toxicity: illuminating the ‘bad’ in the test tube by means of cellular assays?. Trends in Pharmacological Sciences 33:7, pages 353-364.
Crossref
Crossref
Natalie Mesens, Miek Desmidt, Geert R. Verheyen, Sofie Starckx, Siegrid Damsch, Ronald De Vries, Marc Verhemeldonck, Jacky Van Gompel, Ann Lampo & Lieve Lammens. (2012) Phospholipidosis in Rats Treated with Amiodarone: Serum Biochemistry and Whole Genome Micro-Array Analysis Supporting the Lipid Traffic Jam Hypothesis and the Subsequent Rise of the Biomarker BMP. Toxicologic Pathology 40:3, pages 491-503.
Crossref
Crossref
Fan Zhang & Jake Y Chen. (2011) HOMER: a human organ-specific molecular electronic repository. BMC Bioinformatics 12:S10.
Crossref
Crossref
Patrick Y. Muller. (2011) Comparative requirements for exploratory clinical trials — eIND, eCTA and microdosing. Advanced Drug Delivery Reviews 63:7, pages 511-517.
Crossref
Crossref
Pralhad Wangikar, Tausif Ahmed & Subrahmanyam Vangala. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology
1003
1026
.
Uwe Christians, Stephanie McCrery, Jost Klawitter & Jelena Klawitter. 2011. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease
101
176
.
Uwe Christians, Jeska Albuisson, Jost Klawitter & Jelena Klawitter. 2011. Biomarkers of Kidney Disease. Biomarkers of Kidney Disease
39
100
.
Joseph F. Sina & Frank D. Sistare. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.