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Expert Opinion on Drug Metabolism & Toxicology Volume 5, 2009 - Issue 11
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Impact of rat P450 genetic polymorphism on diazepam metabolism

Noriaki Sakai Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18W9 North Ward, Sapporo 060-0818, Japan +81 11 706 6949; +81 11 706 5105; [email protected]
&
Mayumi Ishizuka Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18W9 North Ward, Sapporo 060-0818, Japan +81 11 706 6949; +81 11 706 5105; [email protected]
, PhD
Pages 1421-1433 | Published online: 19 Aug 2009

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Raneem E. Moustafa, Fuad Tarbah, Huda Sulaiman Saeed & Suleiman I. Sharif. (2021) Designer benzodiazepines versus prescription benzodiazepines: can structural relation predict the next step?. Critical Reviews in Toxicology 51:3, pages 249-263.
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Ricardo Jorge Dinis-Oliveira. (2017) Metabolic profile of oxazepam and related benzodiazepines: clinical and forensic aspects. Drug Metabolism Reviews 49:4, pages 451-463.
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Articles from other publishers (12)

Le-le Wang, Xin-xin Ren, Yi He, Guan-feng Cui, Jia-jia Liu, Juan Jia, Jie Cao, Yao Liu, Bin Cong, Zhi-wen Wei & Ke-ming Yun. (2022) Pharmacokinetics of Diazepam and Its Metabolites in Urine of Chinese Participants. Drugs in R&D 22:1, pages 43-50.
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Louise Carton, Candice Niot, Maéva Kyheng, Maud Petrault, Charlotte Laloux, Camille Potey, Marie Lenski, Régis Bordet & Julie Deguil. (2021) Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach. Translational Psychiatry 11:1.
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Kajsa P. Kanebratt, Annika Janefeldt, Liisa Vilén, Anna Vildhede, Kristin Samuelsson, Lucas Milton, Anders Björkbom, Marie Persson, Carina Leandersson, Tommy B. Andersson & Constanze Hilgendorf. (2021) Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies. Journal of Pharmaceutical Sciences 110:1, pages 422-431.
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Yunfang Zhou, Deru Meng, Feifei Chen, Zhengping Wu, Binglan Wang, Shuanghu Wang, Peiwu Geng, Dapeng Dai, Quan Zhou & Weiwen Qiu. (2020) Inhibitory Effect of Imperatorin on the Pharmacokinetics of Diazepam In Vitro and In Vivo. Frontiers in Pharmacology 11.
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Le-le Wang, Xin-xin Ren, Yi He, Guan-feng Cui, Zhi-wen Wei, Juan Jia, Jie Cao, Yao Liu, Bin Cong, Yong Niu & Ke-ming Yun. (2020) Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People. European Journal of Drug Metabolism and Pharmacokinetics.
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Mohammad Azab, Omar F. Khabour, Karem H. Alzoubi & Duaa H. Almomani. (2018) Diazepam induced oxidative DNA damage in cultured human lymphocytes. Journal of King Saud University - Science 30:3, pages 412-416.
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Wojciech Słupski, Małgorzata Trocha & Maria Rutkowska. (2017) Pharmacodynamic and pharmacokinetic interactions between simvastatin and diazepam in rats. Pharmacological Reports 69:5, pages 943-952.
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S. M. M. Nakayama, Y. Ikenaka, A. Hayami, H. Mizukawa, W. S. Darwish, K. P. Watanabe, Y. K. Kawai & M. Ishizuka. (2016) Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam. Journal of Veterinary Pharmacology and Therapeutics 39:5, pages 478-487.
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Tobias Heckel & Laura Suter‐Dick. 2014. Predictive Toxicology. Predictive Toxicology 151 170 .
A. Vettorazzi, E. González-Peñas & A. López de Cerain. (2014) Ochratoxin A kinetics: A review of analytical methods and studies in rat model. Food and Chemical Toxicology 72, pages 273-288.
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Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius & Tommy B. Andersson. (2014) The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions. Drug Metabolism and Disposition 42:3, pages 469-480.
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Elizabeth CM de Lange. 2014. Applied Pharmacometrics. Applied Pharmacometrics 407 449 .

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