Citations (22)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Eva Ramboer, Tamara Vanhaecke, Vera Rogiers & Mathieu Vinken. (2013) Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters. Drug Metabolism Reviews 45:2, pages 196-217.
Read now
Read now
Bo Feng, Jennnifer L LaPerle, George Chang & Manthena VS Varma. (2010) Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state. Expert Opinion on Drug Metabolism & Toxicology 6:8, pages 939-952.
Read now
Read now
Nicola J. Hewitt, María José Gómez Lechón, J. Brian Houston, David Hallifax, Hayley S. Brown, Patrick Maurel, J. Gerald Kenna, Lena Gustavsson, Christina Lohmann, Christian Skonberg, Andre Guillouzo, Gregor Tuschl, Albert P. Li, Edward LeCluyse, Geny M. M. Groothuis & Jan G. Hengstler. (2007) Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies. Drug Metabolism Reviews 39:1, pages 159-234.
Read now
Read now
Articles from other publishers (19)
SY Chang, EJ Weber, KP Van Ness, DL Eaton & EJ Kelly. (2016) Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function. Clinical Pharmacology & Therapeutics 100:5, pages 464-478.
Crossref
Crossref
C. Zetterberg, F. Maltais, L. Laitinen, S. Liao, H. Tsao, A. Chakilam & N. Hariparsad. (2016) VX-509 (Decernotinib)-Mediated CYP3A Time-Dependent Inhibition: An Aldehyde Oxidase Metabolite as a Perpetrator of Drug-Drug Interactions. Drug Metabolism and Disposition 44:8, pages 1286-1295.
Crossref
Crossref
Huaping Tang, Ding Ren Shen, Yong-Hae Han, Yan Kong, Praveen Balimane, Anthony Marino, Mian Gao, Sophie Wu, Dianlin Xie, Matthew G. Soars, Jonathan C. O’Connell, A. David Rodrigues, Litao Zhang & Mary Ellen Cvijic. (2013) Development of Novel, 384-Well High-Throughput Assay Panels for Human Drug Transporters: Drug Interaction and Safety Assessment in Support of Discovery Research. SLAS Discovery 18:9, pages 1072-1083.
Crossref
Crossref
Anders Sonesson & Birgitte Buur Rasmussen. (2013) In Vitro and In Vivo Human Metabolism of Degarelix, a Gonadotropin-Releasing Hormone Receptor Blocker. Drug Metabolism and Disposition 41:7, pages 1339-1346.
Crossref
Crossref
Yurong Lai. 2013. Transporters in Drug Discovery and Development. Transporters in Drug Discovery and Development
633
674
.
Donglu Zhang, Gang Luo, Xinxin Ding & Chuang Lu. (2012) Preclinical experimental models of drug metabolism and disposition in drug discovery and development. Acta Pharmaceutica Sinica B 2:6, pages 549-561.
Crossref
Crossref
Alexander V. LyubimovJasminder Sahi, Cornelia Smith, LaHoma Easterwood, Susan Grepper & Edward LeCluyse. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
53
.
Praveen V. Balimane, Yong‐Hae Han & Saeho Chong. 2012. ADME‐Enabling Technologies in Drug Design and Development. ADME‐Enabling Technologies in Drug Design and Development
161
168
.
. 2012. Pharmacokinetics and Metabolism in Drug Design. Pharmacokinetics and Metabolism in Drug Design
229
250
.
Eskouhie H. Tchaparian, Jessica S. Houghton, Craig Uyeda, Mark P. Grillo & Lixia Jin. (2011) Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes. Drug Metabolism and Disposition 39:12, pages 2387-2394.
Crossref
Crossref
Anders Sonesson, Wolfgang Koechling, Jacek Stalewski, László B. Tankó & Birgitte Buur Rasmussen. (2011) Metabolite Profiles of Degarelix, a New Gonadotropin-Releasing Hormone Receptor Antagonist, in Rat, Dog, and Monkey. Drug Metabolism and Disposition 39:10, pages 1895-1903.
Crossref
Crossref
Pankaj Gupta, Bo Feng & Jack Cook. 2011. Oral Bioavailability. Oral Bioavailability
167
182
.
Annie Lumen, Deborah Silverman, Esteban Martinez, Zeba Ahmed, Deep Agnani, Poulomi Acharya & Joe Bentz. 2011. The Structure of Biological Membranes, Third Edition. The Structure of Biological Membranes, Third Edition
241
272
.
Jana Rohacova, M. Luisa Marin, Alicia Martínez-Romero, José-Enrique O’Connor, M. Jose Gomez-Lechon, M. Teresa Donato, Jose V. Castell & Miguel A. Miranda. (2008) Photophysical characterization and flow cytometry applications of cholylamidofluorescein, a fluorescent bile acid scaffold. Photochemical & Photobiological Sciences 7:7, pages 860-866.
Crossref
Crossref
Punit H. Marathe, Christine Huang & A. David Rodrigues. 2008.
311
328
.
Kelly A. Rose, Vsevolod Kostrubsky & Jasminder Sahi. (2006) Hepatobiliary Disposition in Primary Cultures of Dog and Monkey Hepatocytes. Molecular Pharmaceutics 3:3, pages 266-274.
Crossref
Crossref
Jarkko Rautio, Joan E. Humphreys, Lindsey O. Webster, Anand Balakrishnan, John P. Keogh, Jeevan R. Kunta, Cosette J. Serabjit-Singh & Joseph W. Polli. (2006) IN VITRO P-GLYCOPROTEIN INHIBITION ASSAYS FOR ASSESSMENT OF CLINICAL DRUG INTERACTION POTENTIAL OF NEW DRUG CANDIDATES: A RECOMMENDATION FOR PROBE SUBSTRATES. Drug Metabolism and Disposition 34:5, pages 786-792.
Crossref
Crossref
Michael W. Sinz & Sean Kim. (2006) Stem cells, immortalized cells and primary cells in ADMET assays. Drug Discovery Today: Technologies 3:1, pages 79-85.
Crossref
Crossref
Jasminder Sahi, Michael W. Sinz, Scott Campbell, Rouchelle Mireles, Xianxian Zheng, Kelly A. Rose, Shamsi Raeissi, Muhammed F. Hashim, Yuyang Ye, Sonia M. de Morais, Christopher Black, Meera Tugnait & Laurence H. Keller. (2006) Metabolism and transporter-mediated drug–drug interactions of the endothelin-A receptor antagonist CI-1034. Chemico-Biological Interactions 159:2, pages 156-168.
Crossref
Crossref