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Expert Opinion on Drug Metabolism & Toxicology Volume 7, 2011 - Issue 5
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Drug Evaluations

The pharmacokinetics, pharmacodynamics, clinical efficacy, safety and tolerability of linaclotide

Noel LeeUniversity of Wisconsin School of Medicine and Public Health, Division of Gastroenterology and Hepatology, Centennial Building, 4th floor, 1685 Highland Avenue, Madison, WI 53705, USA
&
Arnold WaldUniversity of Wisconsin School of Medicine and Public Health, Division of Gastroenterology and Hepatology, Centennial Building, 4th floor, 1685 Highland Avenue, Madison, WI 53705, USA. +1 608 263 1995; +1 608 265 5677; [email protected]
, MD (Professor of Medicine)
Pages 651-659 | Published online: 30 Mar 2011

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Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi. (2014) The safety of novel drugs used to treat irritable bowel syndrome. Expert Opinion on Drug Safety 13:5, pages 625-638.
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Jan Tack. (2013) How can we achieve relief of bowel and abdominal symptoms for patients with irritable bowel syndrome with constipation?. Expert Review of Gastroenterology & Hepatology 7:sup1, pages 21-26.
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Stefan Müller-Lissner. (2013) Pharmacokinetic and pharmacodynamic considerations for the current chronic constipation treatments. Expert Opinion on Drug Metabolism & Toxicology 9:4, pages 391-401.
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Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi. (2013) Metabolic and toxicological considerations for the latest drugs used to treat irritable bowel syndrome. Expert Opinion on Drug Metabolism & Toxicology 9:4, pages 403-421.
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Articles from other publishers (14)

Desale Yacob & Carlo Di Lorenzo. (2020) Constipation in Children: A guide to Prompt Diagnosis and Effective Treatment. Current Treatment Options in Pediatrics 6:2, pages 101-115.
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Adam D Farmer, Asbjørn M Drewes, Giuseppe Chiarioni, Roberto De Giorgio, Tony O'Brien, Bart Morlion & Jan Tack. (2019) Pathophysiology and management of opioid‐induced constipation: European expert consensus statement. United European Gastroenterology Journal 7:1, pages 7-20.
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Adam D. Farmer, James K. Ruffle & Anthony R. Hobson. (2018) Linaclotide increases cecal pH, accelerates colonic transit, and increases colonic motility in irritable bowel syndrome with constipation. Neurogastroenterology & Motility 31:2, pages e13492.
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Hans-Dieter Allescher & Wolfram Reeker. 2019. Die Anästhesiologie. Die Anästhesiologie 2055 2071 .
David Stepensky. (2018) Pharmacokinetics of Toxin-Derived Peptide Drugs. Toxins 10:11, pages 483.
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Hans-Dieter Allescher & Wolfram Reeker. 2018. Die Anästhesiologie. Die Anästhesiologie 1 18 .
Miguel Saps & Adrian Miranda. 2017. Gastrointestinal Pharmacology. Gastrointestinal Pharmacology 147 176 .
Timothy A. Hill, Nicholas E. Shepherd, Frederik Diness & David P. Fairlie. (2014) Constraining Cyclic Peptides To Mimic Protein Structure Motifs. Angewandte Chemie International Edition 53:48, pages 13020-13041.
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Timothy A. Hill, Nicholas E. Shepherd, Frederik Diness & David P. Fairlie. (2014) Fixierung cyclischer Peptide: Mimetika von Proteinstrukturmotiven. Angewandte Chemie 126:48, pages 13234-13257.
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P. Layer & V. Stanghellini. (2014) Review article: linaclotide for the management of irritable bowel syndrome with constipation. Alimentary Pharmacology & Therapeutics 39:4, pages 371-384.
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Urspeter Masche. (2013) Linaclotid. pharma-kritik 35:9.
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S. M?ller-Lissner. (2013) Pharmakologische Behandlung der ObstipationPharmacological treatment of constipation. Der Internist 54:4, pages 498-504.
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Stefan Müller-Lissner. (2013) Meist blande, aber extrem belastend. MMW - Fortschritte der Medizin 155:S1, pages 72-78.
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Stuart M Brierley. (2012) Guanylate cyclase-C receptor activation: unexpected biology. Current Opinion in Pharmacology 12:6, pages 632-640.
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