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Drug Evaluations

Pharmacokinetic evaluation of pemetrexed

, MD DMSc MPA (Associate Professor, Chief)
Pages 919-928 | Published online: 21 May 2011

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Read on this site (8)

Giovanni Rossi, Angela Alama, Carlo Genova, Erika Rijavec, Marco Tagliamento, Federica Biello, Simona Coco, Maria Giovanna Dal Bello, Simona Boccardo & Francesco Grossi. (2018) The evolving role of pemetrexed disodium for the treatment of non-small cell lung cancer. Expert Opinion on Pharmacotherapy 19:17, pages 1969-1976.
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Gary Middleton, Cesare Gridelli, Filippo De Marinis, Jean-Louis Pujol, Martin Reck, Rodryg Ramlau, Barbara Parente, Thierry Pieters, Carla M. Visseren-Grul, Bélen San Antonio, William J. John, Annamaria Hayden Zimmermann, Nadia Chouaki & Luis Paz-Ares. (2018) Evaluation of changes in renal function in PARAMOUNT: a phase III study of maintenance pemetrexed plus best supportive care versus placebo plus best supportive care after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer. Current Medical Research and Opinion 34:5, pages 865-871.
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Berrin Küçüktürkmen, Burcu Devrim, Ongun M. Saka, Şükran Yilmaz, Taibe Arsoy & Asuman Bozkir. (2017) Co-delivery of pemetrexed and miR-21 antisense oligonucleotide by lipid-polymer hybrid nanoparticles and effects on glioblastoma cells. Drug Development and Industrial Pharmacy 43:1, pages 12-21.
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Weiyou Zhu, Oluf Dimitri Røe, Chen Wu, Wei Li, Renhua Guo, Yanhong Gu, Yiqian Liu, Yongqian Shu & Xiaofeng Chen. (2015) Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: a retrospective study. Journal of Chemotherapy 27:4, pages 221-226.
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Xin Li, Sen Wei & Jun Chen. (2014) Critical appraisal of pemetrexed in the treatment of NSCLC and metastatic pulmonary nodules. OncoTargets and Therapy 7, pages 937-945.
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Carlo Genova, Erika Rijavec, Anna Truini, Simona Coco, Claudio Sini, Giulia Barletta, Maria Giovanna Dal Bello, Angela Alama, Grazia Savarino, Paolo Pronzato, Francesco Boccardo & Francesco Grossi. (2013) Pemetrexed for the treatment of non-small cell lung cancer. Expert Opinion on Pharmacotherapy 14:11, pages 1545-1558.
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M Morotti, M Valenzano Menada, PL Venturini, S Mammoliti & S Ferrero. (2012) Pemetrexed disodium in ovarian cancer treatment. Expert Opinion on Investigational Drugs 21:4, pages 437-449.
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Articles from other publishers (8)

Maria Joseph, Arun Chandrasekharan & Muhammed Fayiz. (2022) A review of the pharmacokinetic and polymorphic profiles of pemetrexed and their influence on its activity. Cancer Research, Statistics, and Treatment 5:4, pages 785.
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Binsheng He, Jialiang Yang, Geng Tian, Pingping Bing & Jidong Lang. (2021) Detecting TYMS Tandem Repeat Polymorphism by the PSSD Method Based on Next-generation Sequencing. Current Bioinformatics 15:10, pages 1153-1159.
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Wang Chun Kwok, Tan Fong Cheong, Ka Yan Chiang, James Chung Man Ho, David Chi Leung Lam, Mary Sau Man Ip & Terence Chi Chun Tam. (2021) Haematological toxicity of pemetrexed in patients with metastatic non-squamous non-small cell carcinoma of lung with third-space fluid. Lung Cancer 152, pages 15-20.
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Zhenyu Pan, Guozi Yang, Jiuwei Cui, Wei Li, Yu Li, Pengxiang Gao, Tongchao Jiang, Yanan Sun, Lihua Dong, Yuanyuan Song & Gang Zhao. (2019) A Pilot Phase 1 Study of Intrathecal Pemetrexed for Refractory Leptomeningeal Metastases From Non-small-cell Lung Cancer. Frontiers in Oncology 9.
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David Badrudin, Lucas Sideris, Camille Perrault‐Mercier, Julien Hubert, François A. Leblond & Pierre Dubé. (2018) Comparison of open and closed abdomen techniques for the delivery of intraperitoneal pemetrexed using a murine model. Journal of Surgical Oncology 117:6, pages 1318-1322.
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Li‐Yan Zhou, Ye‐Hui Shi, Yong‐Sheng Jia & Zhong‐Sheng Tong. (2015) Potential role of pemetrexed in metastatic breast cancer patients pre‐treated with anthracycline or taxane. Chronic Diseases and Translational Medicine 1:1, pages 27-35.
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Jan Nyrop Jakobsen, Eric Santoni-Rugiu & Jens Benn Sørensen. (2014) Thymidylate synthase protein expression levels remain stable during paclitaxel and carboplatin treatment in non-small cell lung cancer. Journal of Cancer Research and Clinical Oncology 140:4, pages 645-652.
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Young Saing Kim, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn & Keunchil Park. (2013) The optimal duration of vitamin supplementation prior to the first dose of pemetrexed in patients with non-small-cell lung cancer. Lung Cancer 81:2, pages 231-235.
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