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Expert Opinion on Drug Metabolism & Toxicology Volume 8, 2012 - Issue 10
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Reviews

ADMET considerations for phosphodiesterase-5 inhibitors

Mohammad Amin RezvanfarTehran University of Medical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences Research Center (PSRC), Department of Toxicology and Pharmacology, Tehran, Iran
,
Hamid Reza RahimiTehran University of Medical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences Research Center (PSRC), Department of Toxicology and Pharmacology, Tehran, Iran
&
Mohammad AbdollahiTehran University of Medical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences Research Center (PSRC), Department of Toxicology and Pharmacology, Tehran, Iran;Tehran University of Medical Sciences, Endocrinology & Metabolism Research Institute, Tehran, Iran;Tehran University of Medical Sciences, Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, and Endocrinology & Metabolism Research Institute, Tehran 1417614411, Iran+ 98 21 66959104; + 98 21 66959104; [email protected]
(Professor)
Pages 1231-1245 | Published online: 07 Jul 2012

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Mohsen Doostmohammadi & Hamid-Reza Rahimi. (2020) ADME and toxicity considerations for tramadol: from basic research to clinical implications. Expert Opinion on Drug Metabolism & Toxicology 16:7, pages 627-640.
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Maliheh Safavi, Maryam Baeeri & Mohammad Abdollahi. (2013) New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurological and inflammatory disorders. Expert Opinion on Drug Discovery 8:6, pages 733-751.
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Marie-Camille Chaumais, Swanny Perrin, Olivier Sitbon, Gérald Simonneau, Marc Humbert & David Montani. (2013) Pharmacokinetic evaluation of sildenafil as a pulmonary hypertension treatment. Expert Opinion on Drug Metabolism & Toxicology 9:9, pages 1193-1205.
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Articles from other publishers (11)

Kishor Vasant Otari, Rupesh J. Patil & Chandrashekhar Devidas Upasani. (2022) Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil. Fundamental & Clinical Pharmacology 37:2, pages 263-274.
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Yu-Bin Lv, Cong Chen, Qi-Ming Yu, Liang Lyu, Yan-Fen Peng & Xiang-Duan Tan. (2022) Synthesis and biological evaluation of novel pentanediamide derivatives as S-adenosyl-l-homocysteine hydrolase inhibitors. Bioorganic & Medicinal Chemistry Letters 72, pages 128880.
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Jie Jack Li. 2020. Medicinal Chemistry for Practitioners. Medicinal Chemistry for Practitioners 225 304 .
Jie Jack Li. 2020. Medicinal Chemistry for Practitioners. Medicinal Chemistry for Practitioners 133 224 .
Pramila Chaubey, Munira Momin & Sujata Sawarkar. (2020) Significance of Ligand-Anchored Polymers for Drug Targeting in the Treatment of Colonic Disorders. Frontiers in Pharmacology 10.
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Young-Guk Na, Jin-Ju Byeon, Hyun Wook Huh, Min-Ki Kim, Young G. Shin, Hong-Ki Lee & Cheong-Weon Cho. (2019) Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats. Pharmaceutics 11:7, pages 354.
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Irena Žuntar, Adela Krivohlavek, Josipa Kosić-Vukšić, Daniel Granato, Danijela Bursać Kovačević & Predrag Putnik. (2018) Pharmacological and toxicological health risk of food (herbal) supplements adulterated with erectile dysfunction medications. Current Opinion in Food Science 24, pages 9-15.
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Smita Pattanaik, Ravimohan S Mavuduru, Arabind Panda, Joseph L Mathew, Mayank M Agarwal, Eu Chang Hwang, Jennifer A Lyon, Shrawan K Singh & Arup K Mandal. (2018) Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia. Cochrane Database of Systematic Reviews 2018:11.
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Zhi-wei Gao, Yun-ting Zhu, Ming-ming Yu, Bin Zan, Jia Liu, Yi-fan Zhang, Xiao-yan Chen, Xue-ning Li & Da-fang Zhong. (2015) Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model. Acta Pharmacologica Sinica 36:12, pages 1528-1536.
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Mohammad A. Rezvanfar, Sepideh Saadat, Habib A. Shojaei Saadi, Parisa Mansoori, Sarah Saeedi, Maziar Gooshe, Maryam Baeeri & Mohammad Abdollahi. (2015) Cellular and molecular mechanisms of pentoxifylline's beneficial effects in experimental polycystic ovary. Theriogenology 83:6, pages 968-977.
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Shilan Mozaffari & Mohammad Abdollahi. (2013) A Review on the Role of Oxidative Stress and Inflammation in Necrotizing Enterocolitis and Benefits of the Phosphodiesterase Inhibitor Pentoxifylline. International Journal of Pharmacology 9:4, pages 245-250.
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