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Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs

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Pages 1565-1577 | Published online: 13 Sep 2012

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Josef Reznicek, Martina Ceckova, Lukas Cerveny, Fabian Müller & Frantisek Staud. (2017) Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters. Xenobiotica 47:1, pages 77-85.
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Ursula Gundert-Remy, Ulrike Bernauer, Brunhilde Blömeke, Barbara Döring, Eric Fabian, Carsten Goebel, Stefanie Hessel, Christine Jäckh, Alfonso Lampen, Franz Oesch, Ernst Petzinger, Wolfgang Völkel & Peter H. Roos. (2014) Extrahepatic metabolism at the body's internal–external interfaces. Drug Metabolism Reviews 46:3, pages 291-324.
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Articles from other publishers (21)

Natascha Schweighofer, Moritz Strasser, Anna Obermayer, Olivia Trummer, Harald Sourij, Caren Sourij & Barbara Obermayer-Pietsch. (2023) Identification of Novel Intronic SNPs in Transporter Genes Associated with Metformin Side Effects. Genes 14:8, pages 1609.
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Emanuela Salvatorelli, Giorgio Minotti & Pierantonio Menna. (2023) NEW TARGETED DRUGS FOR ACUTE MYELOID LEUKEMIA AND ANTIFUNGALS: PHARMACOKINETIC CHALLENGES AND OPPORTUNITIES. Chemotherapy.
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Xiaomei I. Liu, Dionna J. Green, John N. van den Anker, Natella Y. Rakhmanina, Homa K. Ahmadzia, Jeremiah D. Momper, Kyunghun Park, Gilbert J. Burckart & André Dallmann. (2021) Mechanistic Modeling of Placental Drug Transfer in Humans: How Do Differences in Maternal/Fetal Fraction of Unbound Drug and Placental Influx/Efflux Transfer Rates Affect Fetal Pharmacokinetics?. Frontiers in Pediatrics 9.
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Darren Michael Moss, Marco Siccardi & Catia Marzolini. 2018. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions. Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions 49 85 .
Sue-Chih Lee, Vikram Arya, Xinning Yang, Donna A. Volpe & Lei Zhang. (2017) Evaluation of transporters in drug development: Current status and contemporary issues. Advanced Drug Delivery Reviews 116, pages 100-118.
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Yan Li, Jezrael Revalde & James W. Paxton. (2017) The effects of dietary and herbal phytochemicals on drug transporters. Advanced Drug Delivery Reviews 116, pages 45-62.
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Mei Hong. (2017) Biochemical studies on the structure–function relationship of major drug transporters in the ATP-binding cassette family and solute carrier family. Advanced Drug Delivery Reviews 116, pages 3-20.
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Lucy J. Martínez-Guerrero, Mark Morales, Sean Ekins & Stephen H. Wright. (2016) Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1. Molecular Pharmacology 90:3, pages 254-264.
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David J. Wagner, Tao Hu & Joanne Wang. (2016) Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics. Pharmacological Research 111, pages 237-246.
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A. Hubeny, M. Keiser, S. Oswald, G. Jedlitschky, H. K. Kroemer, W. Siegmund & M. Grube. (2016) Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy. Drug Metabolism and Disposition 44:10, pages 1562-1568.
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Anne T. Nies, Katja Damme, Stephan Kruck, Elke Schaeffeler & Matthias Schwab. (2016) Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine. Archives of Toxicology 90:7, pages 1555-1584.
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Xiaojie Jin, Yonghua Shao, Qifeng Bai, Weiwei Xue, Huanxiang Liu & Xiaojun Yao. (2016) Insights into conformational regulation of PfMATE transporter from Pyrococcus furiosus induced by alternating protonation state of Asp41 residue: A molecular dynamics simulation study. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:6, pages 1173-1180.
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Ivan Sabolić, Davorka Breljak & Tvrtko Smital. 2016. Organic Cation Transporters. Organic Cation Transporters 217 242 .
Xiaojie Jin, Qifeng Bai, Weiwei Xue, Huanxiang Liu & Xiaojun Yao. (2015) Computational study on the inhibition mechanism of a cyclic peptide MaD5 to PfMATE: Insight from molecular dynamics simulation, free energy calculation and dynamical network analysis. Chemometrics and Intelligent Laboratory Systems 149, pages 81-88.
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Tamanna & Jayashree Ramana. (2015) MATEPRED-A-SVM-Based Prediction Method for Multidrug And Toxin Extrusion (MATE) Proteins. Computational Biology and Chemistry 58, pages 199-204.
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Douglas B. Kell & Stephen G. Oliver. (2014) How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion. Frontiers in Pharmacology 5.
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Serena Marchetti & Jan H. M. Schellens. 2014. Drug Transporters. Drug Transporters 433 471 .
Richard B. Pyles, Kathleen L. Vincent, Marc M. Baum, Barry Elsom, Aaron L. Miller, Carrie Maxwell, Tonyia D. Eaves-Pyles, Guangyu Li, Vsevolod L. Popov, Rebecca J. Nusbaum & Monique R. Ferguson. (2014) Cultivated Vaginal Microbiomes Alter HIV-1 Infection and Antiretroviral Efficacy in Colonized Epithelial Multilayer Cultures. PLoS ONE 9:3, pages e93419.
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Ida Pernicova & Márta Korbonits. (2014) Metformin—mode of action and clinical implications for diabetes and cancer. Nature Reviews Endocrinology 10:3, pages 143-156.
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Jialan Cao, Dana K?rsten, Katrin Krause, Erika Kothe, Karin Martin, Martin Roth & J. Michael K?hler. (2013) Application of micro-segmented flow for two-dimensional characterization of the combinatorial effect of zinc and copper ions on metal-tolerant Streptomyces strains. Applied Microbiology and Biotechnology 97:20, pages 8923-8930.
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Arian Emami Riedmaier, Pascale Fisel, Anne T. Nies, Elke Schaeffeler & Matthias Schwab. (2013) Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects. Trends in Pharmacological Sciences 34:2, pages 126-135.
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