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Tobacco smoking effect on HIV-1 pathogenesis: role of cytochrome P450 isozymes

, BS PhD, , MD PhD (Professor) , , PhD (Professor and Chair) & , PhD (Assistant Professor)
Pages 1453-1464 | Published online: 04 Jul 2013

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Santosh Kumar, PSS Rao, Ravindra Earla & Anil Kumar. (2015) Drug–drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems. Expert Opinion on Drug Metabolism & Toxicology 11:3, pages 343-355.
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Linda Chang, Huajun Liang, Suresh R. Kandel & Johnny J. He. (2020) Independent and Combined Effects of Nicotine or Chronic Tobacco Smoking and HIV on the Brain: A Review of Preclinical and Clinical Studies. Journal of Neuroimmune Pharmacology 15:4, pages 658-693.
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Helen C. Steel, W. D. Francois Venter, Annette J. Theron, Ronald Anderson, Charles Feldman, Luyanda Kwofie, Tanita Cronjé, Natasha Arullapan & Theresa M. Rossouw. (2018) Effects of Tobacco Usage and Antiretroviral Therapy on Biomarkers of Systemic Immune Activation in HIV-Infected Participants. Mediators of Inflammation 2018, pages 1-10.
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Haijun Han, Zhongli Yang, Sulie L. Chang & Ming D. Li. (2018) Modulatory Effects of Nicotine on neuroHIV/neuroAIDS. Journal of Neuroimmune Pharmacology 13:4, pages 467-478.
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Sabina Ranjit, Namita Sinha, Sunitha Kodidela & Santosh Kumar. (2018) Benzo(a)pyrene in Cigarette Smoke Enhances HIV-1 Replication through NF-κB Activation via CYP-Mediated Oxidative Stress Pathway. Scientific Reports 8:1.
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Theresa Winhusen, Daniel J. Feaster, Rui Duan, Jennifer L. Brown, Eric S. Daar, Raul Mandler & Lisa R. Metsch. (2017) Baseline Cigarette Smoking Status as a Predictor of Virologic Suppression and CD4 Cell Count During One-Year Follow-Up in Substance Users with Uncontrolled HIV Infection. AIDS and Behavior 22:6, pages 2026-2032.
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S. Chinnapaiyan, R. Dutta, J. Bala, T. Parira, M. Agudelo, M. Nair & H. J. Unwalla. (2018) Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function. Scientific Reports 8:1.
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Sanjana Haque, Namita Sinha, Sabina Ranjit, Narasimha M. Midde, Fatah Kashanchi & Santosh Kumar. (2017) Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication. Scientific Reports 7:1.
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Santosh Kumar, P.S.S. Rao, Namita Sinha & Narasimha M. Midde. 2016. Neuropathology of Drug Addictions and Substance Misuse. Neuropathology of Drug Addictions and Substance Misuse 179 188 .
Theresa M. Rossouw, Ronald Anderson & Charles Feldman. (2015) Impact of HIV infection and smoking on lung immunity and related disorders. European Respiratory Journal 46:6, pages 1781-1795.
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P. S. S. Rao & Santosh Kumar. (2015) Polycyclic aromatic hydrocarbons and cytochrome P450 in HIV pathogenesis. Frontiers in Microbiology 6.
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Anusha Ande, Carole McArthur, Leo Ayuk, Charles Awasom, Paul Ngang Achu, Annette Njinda, Namita Sinha, P. S. S. Rao, Marisela Agudelo, Anantha Ram Nookala, Stephen Simon, Anil Kumar & Santosh Kumar. (2015) Effect of Mild-to-Moderate Smoking on Viral Load, Cytokines, Oxidative Stress, and Cytochrome P450 Enzymes in HIV-Infected Individuals. PLOS ONE 10:4, pages e0122402.
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Ravinder Earla, Anusha Ande, Carole McArthur, Anil Kumar & Santosh Kumar. (2014) Enhanced Nicotine Metabolism in HIV-1–Positive Smokers Compared with HIV-Negative Smokers: Simultaneous Determination of Nicotine and its Four Metabolites in Their Plasma Using a Simple and Sensitive Electrospray Ionization Liquid Chromatography–Tandem Mass Spectrometry Technique. Drug Metabolism and Disposition 42:2, pages 282-293.
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