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The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications

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Pages 1541-1554 | Published online: 13 Aug 2013

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Tewes Tralau, Juliane Sowada & Andreas Luch. (2015) Insights on the human microbiome and its xenobiotic metabolism: what is known about its effects on human physiology?. Expert Opinion on Drug Metabolism & Toxicology 11:3, pages 411-425.
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Sharoen Yu Ming Lim, Mustafa Alshagga, Cin Kong, Mohammed Abdullah Alshawsh, Salah AbdulRazak Alshehade & Yan Pan. (2022) CYP35 family in Caenorhabditis elegans biological processes: fatty acid synthesis, xenobiotic metabolism, and stress responses. Archives of Toxicology 96:12, pages 3163-3174.
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Willow R. Lindsay, Rute Mendonça, Mathilda Waleij Slight, Maria Prager, Mats X. Andersson, Nicholas I. Mundy & Staffan Andersson. (2022) Seasonal but not sex-biased gene expression of the carotenoid ketolase, CYP2J19 , in the sexually dichromatic southern red bishop ( Euplectes orix ) . Royal Society Open Science 9:8.
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Radim Vrzal. (2021) Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage. International Journal of Molecular Sciences 22:22, pages 12306.
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Daniela Pemp, Leo N. Geppert, Claudia Wigmann, Carolin Kleider, René Hauptstein, Katja Schmalbach, Katja Ickstadt, Harald L. Esch & Leane Lehmann. (2020) Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast. Archives of Toxicology 94:9, pages 3013-3025.
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Jacqueline Wen Hui Leow & Eric Chun Yong Chan. (2019) Atypical Michaelis-Menten kinetics in cytochrome P450 enzymes: A focus on substrate inhibition. Biochemical Pharmacology 169, pages 113615.
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Daniela Pemp, Carolin Kleider, Katja Schmalbach, René Hauptstein, Leo N. Geppert, Claudia Köllmann, Katja Ickstadt, Peter Eckert, Iva Neshkova, Rafael Jakubietz, Harald L. Esch & Leane Lehmann. (2019) Qualitative and quantitative differences in estrogen biotransformation in human breast glandular and adipose tissues: implications for studies using mammary biospecimens. Archives of Toxicology 93:10, pages 2823-2833.
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Marija Herholz, Estela Cepeda, Linda Baumann, Alexandra Kukat, Johannes Hermeling, Sarah Maciej, Karolina Szczepanowska, Victor Pavlenko, Peter Frommolt & Aleksandra Trifunovic. (2019) KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants. Nature Communications 10:1.
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Gerard Clarke, Kiran V. Sandhu, Brendan T. Griffin, Timothy G. Dinan, John F. Cryan & Niall P. Hyland. (2019) Gut Reactions: Breaking Down Xenobiotic–Microbiome Interactions. Pharmacological Reviews 71:2, pages 198-224.
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Andrew J. Annalora, Craig B. Marcus & Patrick L. Iversen. (2017) Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism. Drug Metabolism and Disposition 45:4, pages 375-389.
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Patrick Tarnow, Tewes Tralau & Andreas Luch. (2015) G protein-coupled receptor 30 ligand G-1 increases aryl hydrocarbon receptor signalling by inhibition of tubulin assembly and cell cycle arrest in human MCF-7 cells. Archives of Toxicology 90:8, pages 1939-1948.
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Shu-Ting Pan, Danfeng Xue, Zhi-Ling Li, Zhi-Wei Zhou, Zhi-Xu He, Yinxue Yang, Tianxin Yang, Jia-Xuan Qiu & Shu-Feng Zhou. (2016) Computational Identification of the Paralogs and Orthologs of Human Cytochrome P450 Superfamily and the Implication in Drug Discovery. International Journal of Molecular Sciences 17:7, pages 1020.
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D. R. Davydov. (2016) Molecular organization of the microsomal oxidative system: a new connotation for an old term. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 10:1, pages 10-21.
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Bagavathy Shanmugam Karthikeyan, Mohammad Abdulkader Akbarsha & Subbiah Parthasarathy. (2016) Network analysis and cross species comparison of protein–protein interaction networks of human, mouse and rat cytochrome P450 proteins that degrade xenobiotics. Molecular BioSystems 12:7, pages 2119-2134.
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D.R. Davydov. (2015) Molecular organization of the microsomal oxidative system: a new connotation for an old term. Biomeditsinskaya Khimiya 61:2, pages 176-187.
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Hemantkumar Chavan, Feng Li, Robert Tessman, Kristen Mickey, Kenneth Dorko, Timothy Schmitt, Sean Kumer, Sumedha Gunewardena, Nilesh Gaikwad & Partha Krishnamurthy. (2015) Functional Coupling of ATP-binding Cassette Transporter Abcb6 to Cytochrome P450 Expression and Activity in Liver. Journal of Biological Chemistry 290:12, pages 7871-7886.
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