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Pharmacokinetic and toxicological considerations for the treatment of diabetes in patients with liver disease

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Rianne A. Weersink, David M. Burger, Kelly L. Hayward, Katja Taxis, Joost P.H. Drenth & Sander D. Borgsteede. (2020) Safe use of medication in patients with cirrhosis: pharmacokinetic and pharmacodynamic considerations. Expert Opinion on Drug Metabolism & Toxicology 16:1, pages 45-57.
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Hidayat Hussain, Ivan R. Green, Iftikhar Ali, Ikhlas A. Khan, Zulfiqar Ali, Abdullah M. Al-Sadi & Ishtiaq Ahmed. (2017) Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016). Expert Opinion on Therapeutic Patents 27:9, pages 1061-1072.
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Christoph G. Dietrich, Monika Rau, Daniel Jahn & Andreas Geier. (2017) Changes in drug transport and metabolism and their clinical implications in non-alcoholic fatty liver disease. Expert Opinion on Drug Metabolism & Toxicology 13:6, pages 625-640.
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André J Scheen. (2015) Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes. Expert Opinion on Drug Metabolism & Toxicology 11:6, pages 1005-1020.
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Martha Gonzalez, Laura Goracci, Gabriele Cruciani & Italo Poggesi. (2014) Some considerations on the predictions of pharmacokinetic alterations in subjects with liver disease. Expert Opinion on Drug Metabolism & Toxicology 10:10, pages 1397-1408.
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Articles from other publishers (37)

Anne-Sofie H. Jensen, Henriette Ytting, Marie Winther-Sørensen, Johan Burisch, Annika Bergquist, Lise Lotte Gluud & Nicolai J. Wewer Albrechtsen. (2023) Autoimmune liver diseases and diabetes. European Journal of Gastroenterology & Hepatology 35:9, pages 938-947.
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Laurent Castera & Kenneth Cusi. (2023) Diabetes and cirrhosis: Current concepts on diagnosis and management. Hepatology 77:6, pages 2128-2146.
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Fu-Shun Yen, Ming-Chih Hou, James Cheng-Chung Wei, Ying-Hsiu Shih, Chung Y. Hsu, Chih-Cheng Hsu & Chii-Min Hwu. (2023) Glucagon-like Peptide-1 Receptor Agonist Use in Patients With Liver Cirrhosis and Type 2 Diabetes. Clinical Gastroenterology and Hepatology.
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Maxime Mallet, Cristina Alina Silaghi, Philippe Sultanik, Filomena Conti, Marika Rudler, Vlad Ratziu, Dominique Thabut & Raluca Pais. (2023) Current challenges and future perspectives in treating patients with NAFLD-related cirrhosis. Hepatology.
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Md. Salam, Md. Rana, Prodip Baral, Md. Rahman, Shaheen Ahmed, Rubiya Rahman, Nusaiba Jahan, Tanoy Mazumder, Mohammad Islam & Md. Hussain. (2023) Glipizide has Low Influences on Lipid Index and Major Organs Weight Variation and Considerable Anxiolytic Properties: An in vivo Investigation. Journal of Medical Sciences 23:1, pages 7-17.
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Fu-Shun Yen, Ming-Chih Hou, Jia-Sin Liu, Chih-Cheng Hsu & Chii-Min Hwu. (2023) Severe hypoglycemia in patients with liver cirrhosis and type 2 diabetes. Frontiers in Medicine 9.
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Maria Letizia Petroni, Lucia Brodosi & Giulio Marchesini. (2023) The treatment of diabetes in advanced liver disease: change of a paradigm. Annals of Hepatology 28:1, pages 100772.
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Fu-Shun Yen, Ming-Chih Hou, Chun-Wei Pan, Jia-Sin Liu, Chih-Cheng Hsu & Chii-Min Hwu. (2022) The Risk of Severe Hypoglycemia and Mortality in Patients With Type 2 Diabetes and Discharged With Acute Liver Injury. Diabetes Care.
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Chia-Yen Dai, Tzu-Jung Fang, Wei-Wen Hung, Hui-Ju Tsai & Yi-Chun Tsai. (2022) The Determinants of Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus. Biomedicines 10:7, pages 1487.
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Lucia Brodosi, Salvatore Petta, Maria L. Petroni, Giulio Marchesini & Maria C. Morelli. (2021) Management of Diabetes in Candidates for Liver Transplantation and in Transplant Recipients. Transplantation 106:3, pages 462-478.
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Pankaj Puri & Narendra Kotwal. (2022) An Approach to the Management of Diabetes Mellitus in Cirrhosis: A Primer for the Hepatologist. Journal of Clinical and Experimental Hepatology 12:2, pages 560-574.
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Fu-Shun Yen, Chih-Cheng Hsu, James Cheng-Chung Wei, Ming-Chih Hou & Chii-Min Hwu. (2022) Selection and Warning of Evidence-Based Antidiabetic Medications for Patients With Chronic Liver Disease. Frontiers in Medicine 9.
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Jörg Bojunga & Mireen Friedrich-Rust. (2021) Diabetestherapie bei fortgeschrittenen Lebererkrankungen und LeberzirrhoseDiabetes treatment in advanced liver disease and liver cirrhosis. Der Diabetologe 18:1, pages 26-35.
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Jerome Boursier, Rodolphe Anty, Claire Carette, Bertrand Cariou, Laurent Castera, Cyrielle Caussy, Helene Fontaine, Armand Garioud, Pierre Gourdy, Bruno Guerci, Maeva Guillaume, Niasha Michot, Anne Minello, Dann J Ouizeman, Lawrence Serfaty, Fabrice Bonnet, Bruno Vergès & Jean-Michel Petit. (2021) Management of diabetes mellitus in patients with cirrhosis: An overview and joint statement. Diabetes & Metabolism 47:5, pages 101272.
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Fu-Shun Yen, Jung-Nien Lai, James Cheng-Chung Wei, Lu-Ting Chiu, Chii-Min Hwu, Ming-Chih Hou & Chih-Cheng Hsu. (2020) Sulfonylureas may be useful for glycemic management in patients with diabetes and liver cirrhosis. PLOS ONE 15:12, pages e0243783.
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Kelly L. Hayward & Rianne A. Weersink. (2020) Improving Medication‐Related Outcomes in Chronic Liver Disease. Hepatology Communications 4:11, pages 1562-1577.
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Jörg Bojunga. (2020) Diabetestherapie bei nichtalkoholischer Fettlebererkrankung und LeberzirrhoseDiabetes therapy in nonalcoholic fatty liver disease and liver cirrhosis. Der Gastroenterologe 15:2, pages 96-105.
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Eun Yi Cho, Jee-Yeon Ryu, Han A. Reum Lee, Shin Hee Hong, Hye Sun Park, Kwan Soo Hong, Sang-Gyu Park, Hong Pyo Kim & Tae-Jong Yoon. (2019) Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes. Journal of Nanobiotechnology 17:1.
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R. Chawla, B. M. Makkar, S. Aggarwal, S. Bajaj, A. K. Das, S. Ghosh, A. Gupta, S. Gupta, S. Jaggi, J. Jana, J. Keswadev, S. Kalra, P. Keswani, V. Kumar, A. Maheshwari, A. Moses, C. L. Nawal, J. Panda, V. Panikar, G. D. Ramchandani, P. V. Rao, B. Saboo, R. Sahay, K. R. Setty, V. Viswanathan, SR Aravind, S Banarjee, A Bhansali, HB Chandalia, S Das, OP Gupta, S Joshi, A Kumar, KM Kumar, SV Madhu, A Mittal, V Mohan, C Munichhoodappa, A Ramachandran, BK Sahay, J Sai, V Seshiah & AH Zargar. (2019) RSSDI consensus recommendations on insulin therapy in the management of diabetes. International Journal of Diabetes in Developing Countries 39:S2, pages 43-92.
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Athanasia Papazafiropoulou & Andreas Melidonis. (2019) Antidiabetic agents in patients with hepatic impairment. World Journal of Meta-Analysis 7:8, pages 380-388.
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Matteo Tacelli, Ciro Celsa, Bianca Magro, Aurora Giannetti, Grazia Pennisi, Federica Spatola & Salvatore Petta. (2018) Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once?. Pharmaceuticals 11:4, pages 121.
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Chia-Ter Chao, Jui Wang, Jenq-Wen Huang & Kuo-Liong Chien. (2018) Acarbose Use and Liver Injury in Diabetic Patients With Severe Renal Insufficiency and Hepatic Diseases: A Propensity Score-Matched Cohort Study. Frontiers in Pharmacology 9.
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Chunmei Xu, Junyu Zhao, Xiaojun Zhou, Rui Zhang, Tianyue Xie, Zhiwei Zou, Lin Liao & Jianjun Dong. (2018) Thiazolidinediones versus metformin on improving abnormal liver enzymes in patients with type 2 diabetes mellitus: a meta-analysis. Oncotarget 9:15, pages 12389-12399.
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L. Yu. Morgunov. (2017) DIABETES MELLITUS IN PATIENTS WITH LIVER CIRRHOSIS: NEW TREATMENT OPTIONS. Research'n Practical Medicine Journal 4:3, pages 75-85.
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André J. Scheen. (2016) Pharmacokinetic Characteristics and Clinical Efficacy of an SGLT2 Inhibitor Plus DPP-4 Inhibitor Combination Therapy in Type 2 Diabetes. Clinical Pharmacokinetics 56:7, pages 703-718.
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Chalermrat Bunchorntavakul & K. Rajender Reddy. (2017) Drug Hepatotoxicity. Clinics in Liver Disease 21:1, pages 115-134.
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Nobuya Inagaki, Wayne H.-H. Sheu, David R. Owens, Susanne Crowe, Amit Bhandari, Yan Gong & Sanjay Patel. (2016) Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials. Journal of Diabetes and its Complications 30:8, pages 1622-1630.
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Joan S. Grant & Lucinda J. Graven. (2016) Progressing From Metformin to Sulfonylureas or Meglitinides. Workplace Health & Safety 64:9, pages 433-439.
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André J. Scheen. (2016) Precision medicine: The future in diabetes care?. Diabetes Research and Clinical Practice 117, pages 12-21.
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Filomena S. G. Silva, Paulo J. Oliveira & Maria F. Duarte. (2016) Oleanolic, Ursolic, and Betulinic Acids as Food Supplements or Pharmaceutical Agents for Type 2 Diabetes: Promise or Illusion?. Journal of Agricultural and Food Chemistry 64:15, pages 2991-3008.
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Diego García-Compeán, José Alberto González-González, Fernando Javier Lavalle-González, Emmanuel Irineo González-Moreno, Jesús Zacarías Villarreal-Pérez & Héctor J. Maldonado-Garza. (2015) Current Concepts in Diabetes Mellitus and Chronic Liver Disease: Clinical Outcomes, Hepatitis C Virus Association, and Therapy. Digestive Diseases and Sciences 61:2, pages 371-380.
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Diego García-Compeán, José Alberto González-González, Fernando Javier Lavalle-González, Emmanuel Irineo González-Moreno, Jesús Zacarías Villarreal-Pérez & Héctor Jesús Maldonado-Garza. (2016) Hepatogenous diabetes: Is it a neglected condition in chronic liver disease?. World Journal of Gastroenterology 22:10, pages 2869.
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Diego García-Compeán, José A. González-González, Fernando J. Lavalle-González, Emmanuel I. González-Moreno, Héctor J. Maldonado-Garza & Jesús Z. Villarreal-Pérez. (2015) The treatment of diabetes mellitus of patients with chronic liver disease. Annals of Hepatology 14:6, pages 780-788.
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Wenguang ChangLi ChenGrant M. Hatch. (2015) Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies. Biochemistry and Cell Biology 93:5, pages 479-486.
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John D. Clarke, Anika L. Dzierlenga, Nicholas R. Nelson, Hui Li, Samantha Werts, Michael J. Goedken & Nathan J. Cherrington. (2015) Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis. Diabetes 64:9, pages 3305-3313.
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Jingye Zhou, Jianfeng Xu, Zheng Huang & Minmin Wang. (2015) Transporter-mediated tissue targeting of therapeutic molecules in drug discovery. Bioorganic & Medicinal Chemistry Letters 25:5, pages 993-997.
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André J. Scheen. (2014) Pharmacokinetics in Patients with Chronic Liver Disease and Hepatic Safety of Incretin-Based Therapies for the Management of Type 2 Diabetes Mellitus. Clinical Pharmacokinetics 53:9, pages 773-785.
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