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Expert Opinion on Drug Metabolism & Toxicology Volume 10, 2014 - Issue 11
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Reviews

Effect of drug transporter pharmacogenetics on cholestasis

Christoph G DietrichBethlehem Center of Health, Medical Clinic, Stolberg/Rhld, Germany
&
Andreas GeierUniversity of Würzburg, Division of Hepatology, Department of Internal Medicine II, Oberdürrbacherstrasse 6, D-97080 Würzburg, Germany+49 931 201 40170; +49 931 201 640170; [email protected]
, MD (Professor of Medicine and Hepatology)
Pages 1533-1551 | Published online: 26 Sep 2014

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Petar D. Petrov, M. Leonor Fernández-Murga, Mireia López-Riera, M. José Goméz-Lechón, Jose V. Castell & Ramiro Jover. (2018) Predicting drug-induced cholestasis: preclinical models. Expert Opinion on Drug Metabolism & Toxicology 14:7, pages 721-738.
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Articles from other publishers (15)

Shuting Wang, Jie Bao, Jie Li, Wanfang Li, Mengyin Tian, Caixia Qiu, Fei Pang, Xin Li, Jianbo Yang, Yuchi Hu, Sujuan Wang & Hongtao Jin. (2022) Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway. Molecules 27:9, pages 2647.
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A Halawi, N Ibrahim & R Bitar. (2021) Triggers of benign recurrent intrahepatic cholestasis and its pathophysiology: a review of literature. Acta Gastro Enterologica Belgica 84:3, pages 477-486.
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Birk Poller, Felix Huth, Vlasia Kastrinou‐Lampou, Gerd A. Kullak‐Ublick, Michael Arand & Gian Camenisch. 2021. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity 455 479 .
Na Li, Bijun Wang, Yuhuan Wu, Xia Luo, Zhengyuan Chen, Chuanlan Sang & Tianqin Xiong. (2019) Modification effects of SanWei GanJiang Powder on liver and intestinal damage through reversing bile acid homeostasis. Biomedicine & Pharmacotherapy 116, pages 109044.
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M. Leonor Fernández-Murga, Petar D. Petrov, Isabel Conde, Jose V. Castell, M. José Goméz-Lechón & Ramiro Jover. (2018) Advances in drug-induced cholestasis: Clinical perspectives, potential mechanisms and in vitro systems. Food and Chemical Toxicology 120, pages 196-212.
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Bridgett Knox, Yong Wang, Lora J. Rogers, Jiekun Xuan, Dianke Yu, Huaijin Guan, Jiwei Chen, Tieliu Shi, Baitang Ning, Susan A. Kadlubar & R. Rasoulpour. (2017) A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression. Environmental and Molecular Mutagenesis 59:2, pages 134-143.
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J.E. Manautou & C.I. Ghanem. 2018. Comprehensive Toxicology. Comprehensive Toxicology 215 276 .
Jia-Sheng Wu, Yi-Fei Li, Yuan-Yuan Li, Yan Dai, Wen-Kai Li, Min Zheng, Zheng-Chun Shi, Rong Shi, Tian-Ming Wang, Bing-Liang Ma, Ping Liu & Yue-Ming Ma. (2017) Huangqi Decoction Alleviates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis by Reversing Disordered Bile Acid and Glutathione Homeostasis in Mice. Frontiers in Pharmacology 8.
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Julia Riede, Birk Poller, Jörg Huwyler & Gian Camenisch. (2017) Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations. Drug Metabolism and Disposition 45:5, pages 523-531.
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Monicah A. Otieno, Vasanthi Bhaskaran, Evan Janovitz, Yimer Callejas, William B. Foster, William Washburn, John R. Megill, Lois Lehman-McKeeman & Brian Gemzik. (2017) Mechanisms for Hepatobiliary Toxicity in Rats Treated with an Antagonist of Melanin Concentrating Hormone Receptor 1 (MCHR1). Toxicological Sciences 155:2, pages 379-388.
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Maria Kulecka, Andrzej Habior, Agnieszka Paziewska, Krzysztof Goryca, Michalina Dąbrowska, Filip Ambrozkiewicz, Bożena Walewska-Zielecka, Andrzej Gabriel, Michal Mikula & Jerzy Ostrowski. (2017) Clinical Applicability of Whole-Exome Sequencing Exemplified by a Study in Young Adults with the Advanced Cryptogenic Cholestatic Liver Diseases. Gastroenterology Research and Practice 2017, pages 1-8.
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Pramod B. Mahajan. (2016) Recent Advances in Application of Pharmacogenomics for Biotherapeutics. The AAPS Journal 18:3, pages 605-611.
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Christoph G Dietrich. (2016) Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importance. World Journal of Gastroenterology 22:1, pages 72.
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Larry Tremaine, William Brian, Terrye DelMonte, Stephan Francke, Peter Groenen, Keith Johnson, Lei Li, Kimberly Pearson & Jean-Claude Marshall. (2015) The role of ADME pharmacogenomics in early clinical trials: perspective of the Industry Pharmacogenomics Working Group (I-PWG). Pharmacogenomics 16:18, pages 2055-2067.
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Souzan B. Yanni. 2015. Translational ADMET for Drug Therapy. Translational ADMET for Drug Therapy 63 110 .

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