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Role of pharmacogenetics of drug-metabolizing enzymes in treating osteosarcoma

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Claudia Maria Hattinger, Maria Pia Patrizio, Silvia Luppi, Federica Magagnoli, Piero Picci & Massimo Serra. (2019) Current understanding of pharmacogenetic implications of DNA damaging drugs used in osteosarcoma treatment. Expert Opinion on Drug Metabolism & Toxicology 15:4, pages 299-311.
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Claudia Maria Hattinger, Maria Pia Patrizio, Elisa Tavanti, Silvia Luppi, Federica Magagnoli, Piero Picci & Massimo Serra. (2018) Genetic testing for high-grade osteosarcoma: a guide for future tailored treatments?. Expert Review of Molecular Diagnostics 18:11, pages 947-961.
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Di Liu, Wen Xu, Xi Ding, Yang Yang, Yanlin Lu, Ke Fei & Bo Su. (2017) Caspase 8 polymorphisms contribute to the prognosis of advanced lung adenocarcinoma patients after platinum-based chemotherapy. Cancer Biology & Therapy 18:12, pages 948-957.
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Julia E. Vorontsova, Angelina A. Akishina, Roman O. Cherezov & Olga B. Simonova. (2023) A new insight into the aryl hydrocarbon receptor/cytochrome 450 signaling pathway in MG63, HOS, SAOS2, and U2OS cell lines. Biochimie 207, pages 102-112.
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Marina Sáez‐Belló, Víctor Mangas‐Sanjuán, Mª. Amparo Martínez‐Gómez, Mª. Ángeles López‐Montenegro Soria, Mónica Climente‐Martí & Matilde Merino‐Sanjuán. (2020) Evaluation of ABC gene polymorphisms on the pharmacokinetics and pharmacodynamics of capecitabine in colorectal patients: Implications for dosing recommendations. British Journal of Clinical Pharmacology 87:3, pages 905-915.
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Manuela Piazzi, Snezana Kojic, Cristina Capanni, Nemanja Stamenkovic, Alberto Bavelloni, Oriano Marin, Giovanna Lattanzi, William Blalock & Vittoria Cenni. (2021) Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells. Cancers 13:2, pages 174.
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Alini Trujillo-PaolilloCarolina Salinas-SouzaIndhira Dias-OliveiraAntônio S. PetrilliSílvia R.C. Toledo. (2020) CYP Genotypes Are Associated with Toxicity and Survival in Osteosarcoma Patients . Journal of Adolescent and Young Adult Oncology 9:6, pages 621-627.
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J. E. Vorontsova, A. A. Akishina, R. O. Cherezov & O. B. Simonova. (2021) Functional Activity of Aryl Hydrocarbon Receptor in Human Osteosarcoma Cell Cultures. Moscow University Biological Sciences Bulletin 75:4, pages 247-251.
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Katia Scotlandi, Claudia Maria Hattinger, Evelin Pellegrini, Marco Gambarotti & Massimo Serra. (2020) Genomics and Therapeutic Vulnerabilities of Primary Bone Tumors. Cells 9:4, pages 968.
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Leilei Xu, Lujun Wang, Bingchuan Xue & Shoufeng Wang. (2018) MTHFR variant is associated with high-dose methotrexate-induced toxicity in the Chinese osteosarcoma patients. Journal of Bone Oncology 13, pages 143-147.
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Leilei Xu, Chao Xia, Qi Sun, Fei Sheng, Jin Xiong & Shoufeng Wang. (2018) Variants of FasL and ABCC5 are predictive of outcome after chemotherapy-based treatment in osteosarcoma. Journal of Bone Oncology 12, pages 44-48.
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Roelof Koster, Orestis A. Panagiotou, William A. Wheeler, Eric Karlins, Julie M. Gastier‐Foster, Silvia Regina Caminada de Toledo, Antonio S. Petrilli, Adrienne M. Flanagan, Roberto Tirabosco, Irene L. Andrulis, Jay S. Wunder, Nalan Gokgoz, Ana Patiño‐Garcia, Fernando Lecanda, Massimo Serra, Claudia Hattinger, Piero Picci, Katia Scotlandi, David M. Thomas, Mandy L. Ballinger, Richard Gorlick, Donald A. Barkauskas, Logan G. Spector, Margaret Tucker, D. Hicks Belynda, Meredith Yeager, Robert N. Hoover, Sholom Wacholder, Stephen J. Chanock, Sharon A. Savage & Lisa Mirabello. (2017) Genome‐wide association study identifies the GLDC / IL33 locus associated with survival of osteosarcoma patients . International Journal of Cancer 142:8, pages 1594-1601.
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Alini Trujillo-Paolillo, Francine Tesser-Gamba, Antonio Sergio Petrilli, Maria Teresa de Seixas Alves, Reynaldo Jesus Garcia Filho, Renato de Oliveira & Silvia Regina Caminada de Toledo. (2017) CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response. Oncotarget 8:24, pages 38530-38540.
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D. Matthew Gianferante, Lisa Mirabello & Sharon A. Savage. (2017) Germline and somatic genetics of osteosarcoma — connecting aetiology, biology and therapy. Nature Reviews Endocrinology 13:8, pages 480-491.
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M Serra & C M Hattinger. (2016) The pharmacogenomics of osteosarcoma. The Pharmacogenomics Journal 17:1, pages 11-20.
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Ryan A. Durfee, Maryam Mohammed & Hue H. Luu. (2016) Review of Osteosarcoma and Current Management. Rheumatology and Therapy 3:2, pages 221-243.
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Hanneke I. Vos, Marieke J.H. Coenen, Henk-Jan Guchelaar & Dunja Maroeska W.M. te Loo. (2016) The role of pharmacogenetics in the treatment of osteosarcoma. Drug Discovery Today 21:11, pages 1775-1786.
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S. Scheil-Bertram & V. Krenn. (2016) Sitzungsbericht der AG Knochen-, Gelenk- und WeichgewebspathologieMinutes of the AG Knochen-, Gelenk- und Weichgewebspathologie. Der Pathologe 37:S2, pages 242-246.
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Claudia M. Hattinger, Paola Biason, Erika Iacoboni, Sara Gagno, Marilù Fanelli, Elisa Tavanti, Serena Vella, Stefano Ferrari, Andrea Roli, Rossana Roncato, Luciana Giodini, Katia Scotlandi, Piero Picci, Giuseppe Toffoli & Massimo Serra. (2016) Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma. Oncotarget 7:38, pages 61970-61987.
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Meena Subramanyam & Jaya Goyal. (2016) Translational biomarkers: from discovery and development to clinical practice. Drug Discovery Today: Technologies 21-22, pages 3-10.
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