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Expert Opinion on Drug Metabolism & Toxicology Volume 11, 2015 - Issue 10
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Drug Evaluation

Pharmacokinetics, pharmacodynamics and clinical efficacy of pertuzumab in breast cancer therapy

Andrea RoccaIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Daniele AndreisIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Unit of Biostatistics and Clinical Trials, Via P. Maroncelli 40, 47014 Meldola (FC), Italy
, BSc,
Anna FedeliIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Roberta MaltoniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Samanta SartiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Lorenzo CecconettoIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Elisabetta PietriIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Alessio SchironeIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD,
Sara BravacciniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Biosciences Laboratory, Via P. Maroncelli 40, 47014 Meldola (FC), Italy
, PhD,
Patrizia SerraIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Unit of Biostatistics and Clinical Trials, Via P. Maroncelli 40, 47014 Meldola (FC), Italy
, BSc,
Alberto FarolfiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD &
Dino AmadoriIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Via P. Maroncelli 40, 47014 Meldola (FC), Italy+39 05 4373 9278; +39 05 4373 9249; [email protected]
, MD show all
Pages 1647-1663 | Published online: 26 Aug 2015

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Nadia Saoudi Gonzalez, Daniel López, Diego Gómez, Javier Ros, Iosune Baraibar, Francesc Salva, Josep Tabernero & Elena Élez. (2022) Pharmacokinetics and pharmacodynamics of approved monoclonal antibody therapy for colorectal cancer. Expert Opinion on Drug Metabolism & Toxicology 18:11, pages 755-767.
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Guangwen Liu, Zhongnan Xu, Wei Yang, Jinling Xue, Yanli Wang, Zhengzhi Liu, Yingzi Cui, Xinyao Qu, Tianying Chang, Shuang Yu, Yang Cheng, Yannan Zhou, Jiahui Chen, Qing Ren, Wanhua Wang, Qiaohuan Deng, Zeyu Wang & Haimiao Yang. (2022) A randomized, double-blind, single-dose, single-center, parallel phase I clinical study comparing the pharmacokinetics, immunogenicity, safety, and tolerance of pertuzumab injection and Perjeta® in healthy Chinese male subjects. Expert Opinion on Biological Therapy 22:2, pages 187-195.
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Matteo Lambertini, Noam F. Pondé, Cinzia Solinas & Evandro de Azambuja. (2017) Adjuvant trastuzumab: a 10-year overview of its benefit. Expert Review of Anticancer Therapy 17:1, pages 61-74.
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Articles from other publishers (7)

Takuo Ogihara, Kenta Mizoi & Akiko Ishii-Watabe. (2023) Pharmacokinetics of Biopharmaceuticals: Their Critical Role in Molecular Design. Biomedicines 11:5, pages 1456.
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Kelly M Gaertner, Indu G Poornima & Christie Hilton. (2021) Trastuzumab and pertuzumab in hemodialysis: A case report. Journal of Oncology Pharmacy Practice 27:7, pages 1799-1801.
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Semir Vranic, Farhan S. Cyprian, Zoran Gatalica & Juan Palazzo. (2021) PD-L1 status in breast cancer: Current view and perspectives. Seminars in Cancer Biology 72, pages 146-154.
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Angelo Paci, Aude Desnoyer, Julia Delahousse, Louis Blondel, Christophe Maritaz, Nathalie Chaput, Olivier Mir & Sophie Broutin. (2020) Pharmacokinetic/pharmacodynamic relationship of therapeutic monoclonal antibodies used in oncology: Part 1, monoclonal antibodies, antibody-drug conjugates and bispecific T-cell engagers. European Journal of Cancer 128, pages 107-118.
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Andrea Nicolini, Vivian Barak, Piermario Biava, Paola Ferrari, Giuseppe Rossi & Angelo Carpi. (2019) The Use of Immunotherapy to Treat Metastatic Breast Cancer. Current Medicinal Chemistry 26:6, pages 941-962.
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Zheng Lu, Jennifer Sheng & Wenhui Zhang. 2017. Protein Therapeutics. Protein Therapeutics 311 340 .
Hanine Lattouf, Coralie Poulard, Isabelle Treilleux, Nader Hussein, Mona Diab-Assaf & Muriel Le Romancer. (2016) LKB1, A New Biomarker in Breast Cancer. Journal of Cancer Therapy 07:10, pages 690-699.
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