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Original Research

Ethnic sensitivity assessment – pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs

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Takafumi Ide, Amit Roy, Yasuhiko Imai & Heather E. Vezina. (2020) Model‐Based Determination of Elotuzumab Pharmacokinetics in Japanese Patients With Multiple Myeloma Incorporating Time‐Varying M Protein. The Journal of Clinical Pharmacology 61:1, pages 64-73.
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Iris Rajman, Masaru Hirano, Wataru Honma & Sylvia Zhao. (2020) New paradigm for expediting drug development in Asia. Drug Discovery Today 25:3, pages 491-496.
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Chen Wang, Qingshan Zheng, Mingqiang Zhang & Hong Lu. (2018) Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of evolocumab between Caucasian and Asian populations. British Journal of Clinical Pharmacology 85:1, pages 114-125.
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E Chigutsa, AJ Long & JE Wallin. (2017) Exposure-Response Analysis of Necitumumab Efficacy in Squamous Non-Small Cell Lung Cancer Patients. CPT: Pharmacometrics & Systems Pharmacology 6:8, pages 560-568.
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Chunze Li, Bei Wang, Dan Lu, Jin Y. Jin, Yuying Gao, Kiyoshi Matsunaga, Yuriko Igawa, Ihsan Nijem, Michael Lu, Alexander Strasak, Nataliya Chernyukhin & Sandhya Girish. (2016) Ethnic sensitivity assessment of the antibody–drug conjugate trastuzumab emtansine (T-DM1) in patients with HER2-positive locally advanced or metastatic breast cancer. Cancer Chemotherapy and Pharmacology 78:3, pages 547-558.
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O. Nemoto, M. Furue, H. Nakagawa, M. Shiramoto, R. Hanada, S. Matsuki, S. Imayama, M. Kato, I. Hasebe, K. Taira, M. Yamamoto, R. Mihara, K. Kabashima, T. Ruzicka, J. Hanifin & Y. Kumagai. (2016) The first trial of CIM331, a humanized antihuman interleukin-31 receptor A antibody, in healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomized, double-blind, placebo-co. British Journal of Dermatology 174:2, pages 296-304.
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