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Expert Opinion on Drug Metabolism & Toxicology Volume 12, 2016 - Issue 1
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The pregnane X receptor in tuberculosis therapeutics

Amina I ShehuCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA15261, USA
,
Guangming LiDepartment of Hepatology, the 6 People’s Hospital of Zhengzhou, the Hospital for Infectious Diseases in Henan Province, Zhengzhou, China
,
Wen XieCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA15261, USA
&
Xiaochao MaCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA15261, USACorrespondence[email protected]
Pages 21-30 | Published online: 05 Dec 2015

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Helena Rabie, Eric H. Decloedt, Anthony J. Garcia-Prats, Mark F. Cotton, Lisa Frigati, Marc Lallemant, Anneke Hesseling & H. Simon Schaaf. (2017) Antiretroviral treatment in HIV-infected children who require a rifamycin-containing regimen for tuberculosis. Expert Opinion on Pharmacotherapy 18:6, pages 589-598.
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Articles from other publishers (12)

Harvesh Kumar Rana, Amit Kumar Singh & Abhay Kumar Pandey. (2023) Therapeutic Potential of Morin Hydrate Against Rifampicin Induced Hepato and Renotoxicity in Albino Wistar Rats: Modulation of Organ Function, Oxidative Stress and Inflammatory Response. Indian Journal of Clinical Biochemistry.
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Zdeněk Dvořák, Hao Li & Sridhar Mani. (2023) Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future. Drug Metabolism and Disposition 51:2, pages 219-227.
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Jayaprakasam Bolleddula, Sathej Gopalakrishnan, Ping Hu, Jennifer Dong & Karthik Venkatakrishnan. (2022) Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies . Clinical and Translational Science 15:9, pages 2075-2095.
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Moumita Dutta, Joe Jongpyo Lim & Julia Yue Cui. (2022) Pregnane X Receptor and the Gut-Liver Axis: A Recent Update. Drug Metabolism and Disposition 50:4, pages 478-491.
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Sergio C. Chai & Taosheng Chen. 2021. Nuclear Receptors. Nuclear Receptors 179 198 .
Sergio C. Chai, William C. Wright & Taosheng Chen. (2019) Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer. Medicinal Research Reviews 40:3, pages 1061-1083.
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Andrea Calcagno, Jessica Cusato, Christine Sekaggya‐Wiltshire, Amrei Braun, Ilaria Motta, Grace Turyasingura, Barbara Castelnuovo, Jan Fehr, Giovanni Di Perri & Mohammed Lamorde. (2019) The Influence of Pharmacogenetic Variants in HIV/Tuberculosis Coinfected Patients in Uganda in the SOUTH Study. Clinical Pharmacology & Therapeutics 106:2, pages 450-457.
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Chrissy M. Leopold Wager, Eusondia Arnett & Larry S. Schlesinger. (2019) Mycobacterium tuberculosis and macrophage nuclear receptors: What we do and don't know. Tuberculosis 116, pages S98-S106.
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Lucky Legbosi Nwidu & Raphael Ellis Teme. (2018) Hot aqueous leaf extract of Lasianthera africana (Icacinaceae) attenuates rifampicin-isoniazid-induced hepatotoxicity. Journal of Integrative Medicine 16:4, pages 263-272.
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Ella Bhagyaraj, Drishti Tiwari, Nancy Ahuja, Ravikanth Nanduri, Ankita Saini, Rashi Kalra, Sumit Kumar, Ashok Kumar Janmeja & Pawan Gupta. (2018) A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin. Journal of Biological Chemistry 293:10, pages 3747-3757.
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Liuqin He, Xihong Zhou, Niu Huang, Huan Li, Tiejun Li, Kang Yao, Yanan Tian, Chien-An Andy Hu & Yulong Yin. (2017) Functions of pregnane X receptor in self-detoxification. Amino Acids 49:12, pages 1999-2007.
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Udhaya Lavinya Baskaran & Evan Prince Sabina. (2017) Clinical and experimental research in antituberculosis drug-induced hepatotoxicity: a review. Journal of Integrative Medicine 15:1, pages 27-36.
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