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Expert Opinion on Drug Metabolism & Toxicology Volume 12, 2016 - Issue 4
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Drug Evaluation

Pharmacokinetic, pharmacodynamic and clinical evaluation of saxagliptin in type 2 diabetes

Rose AndersonDepartment of Diabetes & Endocrinology, Morriston Hospital, ABM University Health Board, Swansea, UK
,
Jennifer HayesDepartment of Diabetes & Endocrinology, Morriston Hospital, ABM University Health Board, Swansea, UK
&
Jeffrey W. StephensDepartment of Diabetes & Endocrinology, Morriston Hospital, ABM University Health Board, Swansea, UK;Diabetes Research Group, Institute of Life Sciences, Swansea University, Swansea, UKCorrespondence[email protected]
Pages 467-473 | Received 07 Dec 2015, Accepted 10 Feb 2016, Published online: 29 Feb 2016

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Read on this site (4)

Kazuki Orime & Yasuo Terauchi. (2020) Efficacy and safety of saxagliptin for the treatment of type 2 diabetes mellitus. Expert Opinion on Pharmacotherapy 21:17, pages 2101-2114.
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María Molina-Vega, Araceli Muñoz-Garach, José C. Fernández-García & Francisco J. Tinahones. (2018) The safety of DPP-4 inhibitor and SGLT2 inhibitor combination therapies. Expert Opinion on Drug Safety 17:8, pages 815-824.
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André J. Scheen. (2017) Dapagliflozin and saxagliptin tablets for adults with type 2 diabetes. Expert Review of Clinical Pharmacology 10:12, pages 1303-1316.
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André J. Scheen. (2017) Pharmacokinetic drug evaluation of saxagliptin plus dapagliflozin for the treatment of type 2 diabetes. Expert Opinion on Drug Metabolism & Toxicology 13:5, pages 583-592.
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Articles from other publishers (5)

Wanhong Wu, Rongfang Lin, Meng Ke, Lingling Ye & Cuihong Lin. (2023) Physiologically Based Pharmacokinetic Modeling Characterizes the Drug‐Drug Interaction Between Saxagliptin and Rifampicin in Patients With Renal Impairment. The Journal of Clinical Pharmacology.
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Min Wu, Qian‐Qian Li, Hong Zhang, Xiao‐Xue Zhu, Xiao‐Jiao Li, Ying Li, Hai‐Gang Sun & Yan‐Hua Ding. (2021) Safety, Pharmacokinetics, and Pharmacodynamics of a Dipeptidyl Peptidase‐4 Inhibitor: A Randomized, Double‐Blinded, Placebo‐Controlled Daily Administration of Fotagliptin Benzoate for 14 Days for Type 2 Diabetes Mellitus. Clinical Pharmacology in Drug Development 10:6, pages 660-668.
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Maryam Rameshrad, Bibi Marjan Razavi, Gordon A. A. Ferns & Hossein Hosseinzadeh. (2019) Pharmacology of dipeptidyl peptidase-4 inhibitors and its use in the management of metabolic syndrome: a comprehensive review on drug repositioning. DARU Journal of Pharmaceutical Sciences 27:1, pages 341-360.
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David W. Boulton. (2016) Clinical Pharmacokinetics and Pharmacodynamics of Saxagliptin, a Dipeptidyl Peptidase-4 Inhibitor. Clinical Pharmacokinetics 56:1, pages 11-24.
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Yanwei Li, Lin Li & Christian Hölscher. (2016) Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseases. Reviews in the Neurosciences 27:7, pages 689-711.
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