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Review

Transporter-mediated drug interactions: clinical implications and in vitro assessment

Pages 81-92 | Published online: 01 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

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Edoardo Spina, Maria Antonietta Barbieri, Giuseppe Cicala, Antonio Bruno & Jose de Leon. (2020) Clinically relevant drug interactions between newer antidepressants and oral anticoagulants. Expert Opinion on Drug Metabolism & Toxicology 16:1, pages 31-44.
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Jimmy Flarakos, Yancy Du, Helen Gu, Lai Wang, Heidi J. Einolf, Dung Y. Chun, Bing Zhu, Natalia Alexander, Adrienne Natrillo, Imad Hanna, Lillian Ting, Wei Zhou, Kiran Dole, Haiying Sun, Steven J. Kovacs, Daniel S. Stein, S. Ken Tanaka, Stephen Villano & James B. Mangold. (2017) Clinical disposition, metabolism and in vitro drug–drug interaction properties of omadacycline. Xenobiotica 47:8, pages 682-696.
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Lori WE van der Schoor, Henkjan J Verkade, Folkert Kuipers & Johan W Jonker. (2015) New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition. Expert Opinion on Drug Metabolism & Toxicology 11:2, pages 273-293.
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Motoya Suzuki, Hiroshi Komura, Tomonori Yoshikawa, Seiji Enya, Akemi Nagao, Hiroaki Takubo & Motohiro Kogayu. (2014) Characterization of gastrointestinal absorption of digoxin involving influx and efflux transporter in rats: application of mdr1a knockout (−/−) rats into absorption study of multiple transporter substrate. Xenobiotica 44:11, pages 1039-1045.
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Domenico Italiano, Edoardo Spina & Jose de Leon. (2014) Pharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants. Expert Opinion on Drug Metabolism & Toxicology 10:11, pages 1457-1489.
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Edoardo Spina & Jose de Leon. (2014) Clinically relevant interactions between newer antidepressants and second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 10:5, pages 721-746.
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Eve-Irene Lepist & Adrian S Ray. (2012) Renal drug–drug interactions: what we have learned and where we are going. Expert Opinion on Drug Metabolism & Toxicology 8:4, pages 433-448.
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Jan-Shiang Taur, Christopher S. DesJardins, Edgar L. Schuck & Y. Nancy Wong. (2011) Interactions between the chemotherapeutic agent eribulin mesylate (E7389) and P-glycoprotein in CF-1 abcb1a-deficient mice and Caco-2 cells. Xenobiotica 41:4, pages 320-326.
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Grzegorz Kofla, Vincent Turner, Bettina Schulz, Ulrike Storch, Daniela Froelich, Bénédicte Rognon, Alix T. Coste, Dominique Sanglard & Markus Ruhnke. (2011) Doxorubicin induces drug efflux pumps in Candida albicans. Medical Mycology 49:2, pages 132-142.
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Christoph Funk. (2008) The role of hepatic transporters in drug elimination. Expert Opinion on Drug Metabolism & Toxicology 4:4, pages 363-379.
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Rainer Cermak. (2008) Effect of dietary flavonoids on pathways involved in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 4:1, pages 17-35.
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