182
Views
29
CrossRef citations to date
0
Altmetric
Reviews

Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective

Pages 1053-1064 | Published online: 04 Aug 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Yun-Jing Zhang, Wen-Li Zhou, Fei Yu, Qian Wang, Can Peng & Jia-Yi Kan. (2021) Evaluation of the effect of Bovis Calculus Artifactus on eight rat liver cytochrome P450 isozymes using LC-MS/MS and cocktail approach. Xenobiotica 51:9, pages 1010-1018.
Read now
Jessica H. Hartman, Gunnar Boysen & Grover P. Miller. (2013) Cooperative effects for CYP2E1 differ between styrene and its metabolites. Xenobiotica 43:9, pages 755-764.
Read now

Articles from other publishers (27)

Michael Fasullo & Michael Dolan. (2022) The continuing evolution of barcode applications: Functional toxicology to cell lineage. Experimental Biology and Medicine 247:23, pages 2119-2127.
Crossref
Sherif M. Shoieb, Mahmoud A. El-Ghiaty & Ayman O. S. El-Kadi. (2020) Targeting arachidonic acid–related metabolites in COVID-19 patients: potential use of drug-loaded nanoparticles. Emergent Materials 4:1, pages 265-277.
Crossref
Qi-Lin Zhang, Zhi-Xiang Dong, Zhi-Wen Luo, Man Zhang, Xian-Yu Deng, Jun Guo, Feng Wang & Lian-Bing Lin. (2020) The impact of mercury on the genome-wide transcription profile of zebrafish intestine. Journal of Hazardous Materials 389, pages 121842.
Crossref
Mengchen Xu, Tong Zhang, Chao Lv, Qigui Niu, Wansong Zong, Jingchun Tang & Rutao Liu. (2019) Perfluorodecanoic acid-induced oxidative stress and DNA damage investigated at the cellular and molecular levels. Ecotoxicology and Environmental Safety 185, pages 109699.
Crossref
Sherif M. Shoieb, Ahmed A. El-Sherbeni & Ayman O.S. El-Kadi. (2019) Subterminal hydroxyeicosatetraenoic acids: Crucial lipid mediators in normal physiology and disease states. Chemico-Biological Interactions 299, pages 140-150.
Crossref
Abhinav Parashar, Daniel Andrew Gideon & Kelath Murali Manoj. (2018) Murburn Concept: A Molecular Explanation for Hormetic and Idiosyncratic Dose Responses. Dose-Response 16:2, pages 155932581877442.
Crossref
Jessica H. Hartman, Jordan S. Kozal, Richard T. Di Giulio & Joel N. Meyer. (2017) Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like. Environmental Toxicology and Pharmacology 54, pages 142-145.
Crossref
Yong Wang, Dianke Yu, William H. Tolleson, Li-Rong Yu, Bridgett Green, Linjuan Zeng, Yinting Chen, Si Chen, Zhen Ren, Lei Guo, Weida Tong, Huaijin Guan & Baitang Ning. (2017) A systematic evaluation of microRNAs in regulating human hepatic CYP2E1. Biochemical Pharmacology 138, pages 174-184.
Crossref
Jessica H. Hartman, Grover P. Miller, Andres A. Caro, Stephanie D. Byrum, Lisa M. Orr, Samuel G. Mackintosh, Alan J. Tackett, Lee Ann MacMillan-Crow, Lance M. Hallberg, Bill T. Ameredes & Gunnar Boysen. (2017) 1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice. Toxicology 378, pages 114-124.
Crossref
Peter Hlavica. (2017) Challenges in assignment of allosteric effects in cytochrome P450-catalyzed substrate oxidations to structural dynamics in the hemoprotein architecture. Journal of Inorganic Biochemistry 167, pages 100-115.
Crossref
Jessica H. Hartman, Grover P. Miller & Joel N. Meyer. (2017) Toxicological implications of mitochondrial localization of CYP2E1. Toxicology Research 6:3, pages 273-289.
Crossref
Yue Wang, Hong Gao, Xiao-Lin Na, Shu-Ying Dong, Hong-Wei Dong, Jia Yu, Li Jia & Yong-Hui Wu. (2016) Aniline Induces Oxidative Stress and Apoptosis of Primary Cultured Hepatocytes. International Journal of Environmental Research and Public Health 13:12, pages 1188.
Crossref
Ahmed A. El-Sherbeni & Ayman O. S. El-Kadi. (2016) Repurposing Resveratrol and Fluconazole To Modulate Human Cytochrome P450-Mediated Arachidonic Acid Metabolism. Molecular Pharmaceutics 13:4, pages 1278-1288.
Crossref
Yufeng J. Tseng, Bo-Han Su, Ming-Tsung Hsu & Olivia A. Lin. 2016. Frontiers in Molecular Design and Chemical Information Science - Herman Skolnik Award Symposium 2015: Jürgen Bajorath. Frontiers in Molecular Design and Chemical Information Science - Herman Skolnik Award Symposium 2015: Jürgen Bajorath 283 329 .
Jessica H. Hartman, H. Cass Martin, Andres A. Caro, Amy R. Pearce & Grover P. Miller. (2015) Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates. Toxicology 338, pages 47-58.
Crossref
Yan Wang, Qingchuan Zheng, Jilong Zhang, Mo Xie, Jiuyu Zhan & Hongxing Zhang. (2015) How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants. Chemical Research in Chinese Universities 31:6, pages 1029-1038.
Crossref
Jessica H. Hartman, Lynda G. Letzig, Dean W. Roberts, Laura P. James, E.Kim Fifer & Grover P. Miller. (2015) Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures. Biochemical Pharmacology 97:3, pages 341-349.
Crossref
Bo-Han Su, Yi-shu Tu, Chieh Lin, Chi-Yu Shao, Olivia A. Lin & Yufeng J. Tseng. (2015) Rule-Based Prediction Models of Cytochrome P450 Inhibition. Journal of Chemical Information and Modeling 55:7, pages 1426-1434.
Crossref
Syed Subhani & Kaiser Jamil. (2015) Molecular docking of chemotherapeutic agents to CYP3A4 in non-small cell lung cancer. Biomedicine & Pharmacotherapy 73, pages 65-74.
Crossref
Joseph W. Levy, Jessica H. Hartman, Martin D. PerryJr.Jr. & Grover P. Miller. (2015) Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations. Journal of Molecular Graphics and Modelling 56, pages 43-52.
Crossref
Jessica H. Hartman, Katie Knott & Grover P. Miller. (2014) CYP2E1 hydroxylation of aniline involves negative cooperativity. Biochemical Pharmacology 87:3, pages 523-533.
Crossref
Jessica H. Hartman, Amber M. Bradley, Ryan M. Laddusaw, Martin D. PerryJr.Jr. & Grover P. Miller. (2013) Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes. Archives of Biochemistry and Biophysics 537:1, pages 12-20.
Crossref
Jessica H. Hartman, Gunnar Boysen & Grover P. Miller. (2012) CYP2E1 Metabolism of Styrene Involves Allostery. Drug Metabolism and Disposition 40:10, pages 1976-1983.
Crossref
Jayalakshmi Sridhar, Jiawang Liu, Maryam Foroozesh & Cheryl L. Klein Stevens. (2012) Insights on Cytochrome P450 Enzymes and Inhibitors Obtained Through QSAR Studies. Molecules 17:8, pages 9283-9305.
Crossref
Thomas Peyret & Kannan Krishnan. (2012) Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans. Journal of Toxicology 2012, pages 1-22.
Crossref
Jue Li, Dong-Qing Wei, Jing-Fang Wang & Yi-Xue Li. (2011) A Negative Cooperativity Mechanism of Human CYP2E1 Inferred from Molecular Dynamics Simulations and Free Energy Calculations. Journal of Chemical Information and Modeling 51:12, pages 3217-3225.
Crossref
Ilia G. Denisov, Daniel J. Frank & Stephen G. Sligar. (2009) Cooperative properties of cytochromes P450. Pharmacology & Therapeutics 124:2, pages 151-167.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.