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Expert Opinion on Drug Discovery Volume 4, 2009 - Issue 5
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Case History

Early development of the Toll-like receptor 9 agonist, PF-3512676, for the treatment of patients with advanced cancers

Ahmad A Tarhini Assistant Professor of Medicine University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Centre Avenue, RM 555 Pittsburgh, Pennsylvania, USA +1 412 648 6507; +1 412 648 6579; [email protected]
, MD MSc,
John M Kirkwood Professor and Vice Chair of Clinical Research, Director of Melanoma Program University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
, MD &
Arthur M Krieg Chief Scientific Officer of Research Technology Pfizer Inc., Cambridge, Massachusetts, USA
, MD
Pages 587-603 | Published online: 07 May 2009

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Ahmad A Tarhini & Fatima Iqbal. (2010) CTLA-4 blockade: therapeutic potential in cancer treatments. OncoTargets and Therapy 3, pages 15-25.
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Articles from other publishers (4)

Sumana Narayanan & Joseph J. Skitzki. 2020. Cancer Immunology. Cancer Immunology 363 378 .
Kerstin Kapp, Barbara Volz, Michael A. Curran, Detlef Oswald, Burghardt Wittig & Manuel Schmidt. (2019) EnanDIM - a novel family of L-nucleotide-protected TLR9 agonists for cancer immunotherapy. Journal for ImmunoTherapy of Cancer 7:1.
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Julie A. Alosi, Scott W. Baldwin, Jacqueline Oxenberg & Joseph J. Skitzki. 2015. Cancer Immunology. Cancer Immunology 319 332 .
Donald W. Northfelt, Ramesh K. Ramanathan, Peter A. Cohen, Daniel D. Von Hoff, Glen J. Weiss, Gregory N. Dietsch, Kristi L. Manjarrez, Tressa D. Randall & Robert M. Hershberg. (2014) A Phase I Dose-Finding Study of the Novel Toll-like Receptor 8 Agonist VTX-2337 in Adult Subjects with Advanced Solid Tumors or Lymphoma. Clinical Cancer Research 20:14, pages 3683-3691.
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