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Animal models of anorexia and cachexia

, MD MS MCR (Assistant Professor of Pediatrics)
Pages 1145-1155 | Published online: 06 Oct 2009

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Hui-Feng Gao, Lian-Yu Chen, Chien-Shan Cheng, Hao Chen, Zhi-Qiang Meng & Zhen Chen. (2019) SLC5A1 promotes growth and proliferation of pancreatic carcinoma via glucose-dependent AMPK/mTOR signaling. Cancer Management and Research 11, pages 3171-3185.
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Masaaki Konishi, Nicole Ebner, Stephan von Haehling, Stefan D Anker & Jochen Springer. (2015) Developing models for cachexia and their implications in drug discovery. Expert Opinion on Drug Discovery 10:7, pages 743-752.
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Jochen Springer & Stefan D Anker. (2010) The underestimated impact of cachexia. Expert Opinion on Drug Discovery 5:1, pages 1-3.
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Kaitlin Giles, Chen Guan, Thomas R. Jagoe & Vera Mazurak. (2016) Diet composition as a source of variation in experimental animal models of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle 7:2, pages 110-125.
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Serkan Kir, Hirotaka Komaba, Ana P. Garcia, Konstantinos P. Economopoulos, Wei Liu, Beate Lanske, Richard A. Hodin & Bruce M. Spiegelman. (2016) PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. Cell Metabolism 23:2, pages 315-323.
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Valentina Sala, Stefano Gatti, Simona Gallo, Enzo Medico, Daniela Cantarella, James Cimino, Antonio Ponzetto & Tiziana Crepaldi. (2016) A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart. BioMed Research International 2016, pages 1-13.
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Ana I. Faustino-Rocha, Rita Ferreira, Paula A. Oliveira, Adelina Gama & Mário Ginja. (2015) N-Methyl-N-nitrosourea as a mammary carcinogenic agent. Tumor Biology 36:12, pages 9095-9117.
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Francesco Elia Marino, Gail Risbridger & Elspeth Gold. (2015) Activin-β C modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways . Journal of Cachexia, Sarcopenia and Muscle 6:4, pages 365-380.
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Stephanie H. Greco, Lena Tomkötter, Anne-Kristin Vahle, Rae Rokosh, Antonina Avanzi, Syed Kashif Mahmood, Michael Deutsch, Sara Alothman, Dalia Alqunaibit, Atsuo Ochi, Constantinos Zambirinis, Tasnima Mohaimin, Mauricio Rendon, Elliot Levie, Mridul Pansari, Alejandro Torres-Hernandez, Donnele Daley, Rocky Barilla, H. Leon Pachter, Daniel Tippens, Hassan Malik, Allal Boutajangout, Thomas Wisniewski & George Miller. (2015) TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia. PLOS ONE 10:7, pages e0132786.
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Young Kwon, Wei Song, Ilia A. Droujinine, Yanhui Hu, John M. Asara & Norbert Perrimon. (2015) Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2. Developmental Cell 33:1, pages 36-46.
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Katja Cvan Trobec, Mojca Kerec Kos, Jurij Trontelj, Iztok Grabnar, Anika Tschirner, Sandra Palus, Stefan D. Anker, Jochen Springer & Mitja Lainscak. (2015) Influence of cancer cachexia on drug liver metabolism and renal elimination in rats. Journal of Cachexia, Sarcopenia and Muscle 6:1, pages 45-52.
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Ronan Thibault, Sylvain Chanséaume, Kasra Azarnoush, Christelle Guillet, Christophe Giraudet, Véronique Patrac, Jean-René Lusson, Noël Cano, Yves Boirie & Stéphane Walrand. (2014) Mitochondrial protein synthesis is increased in oxidative skeletal muscles of rats with cardiac cachexia. Nutrition Research 34:3, pages 250-257.
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Mark D. DeBoer. (2011) Ghrelin and cachexia: Will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes?. Molecular and Cellular Endocrinology 340:1, pages 97-105.
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Marat Fudim, Gabriel Wagman, Rebecca Altschul, Evin Yucel, Michelle Bloom & Timothy J. Vittorio. (2011) Pathophysiology and Treatment Options for Cardiac Anorexia. Current Heart Failure Reports 8:2, pages 147-153.
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