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Leadhopping – and beyond

Pages 311-321 | Published online: 06 Sep 2006

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S.G. Bhansali & V.M. Kulkarni. (2014) Combined 2D and 3D-QSAR, molecular modelling and docking studies of pyrazolodiazepinones as novel phosphodiesterase 2 inhibitors. SAR and QSAR in Environmental Research 25:11, pages 905-937.
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Vijayalakshmi Ezhilarasan, Ankush Jadhav & Archana Pan. (2014) Screening of potent antibacterial agents targeting Clostridium difficile virulence factor toxin B: an in silico approach. Medicinal Chemistry Research 23:10, pages 4464-4481.
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Richard D. Cramer & Bernd Wendt. (2014) Template CoMFA: The 3D-QSAR Grail?. Journal of Chemical Information and Modeling 54:2, pages 660-671.
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Ting-Lan Chiu, Kimberly M. Maize & Elizabeth A. Amin. 2013. In Silico Models for Drug Discovery. In Silico Models for Drug Discovery 177 184 .
Haitao Ji. 2011. ADMET for Medicinal Chemists. ADMET for Medicinal Chemists 417 485 .
Sarah R. Langdon, Peter Ertl & Nathan Brown. (2010) Bioisosteric Replacement and Scaffold Hopping in Lead Generation and Optimization. Molecular Informatics 29:5, pages 366-385.
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Ting-Lan Chiu, Jonathan Solberg, Satish Patil, Todd W. Geders, Xia Zhang, Subhashree Rangarajan, Rawle Francis, Barry C. Finzel, Michael A. Walters, Derek J. Hook & Elizabeth A. Amin. (2009) Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening. Journal of Chemical Information and Modeling 49:12, pages 2726-2734.
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Jack Andrew Bikker & Lakshmi S. Narasimhan. 2010. Lead-Seeking Approaches. Lead-Seeking Approaches 85 124 .

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