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Targeting kinases for the treatment of inflammatory diseases

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Pages 867-881 | Published online: 15 Jul 2010

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Karianne Fredenfeldt Lind, Bjarne Østerud, Espen Hansen, Trond Ø. Jørgensen & Jeanette Hammer Andersen. (2015) The immunomodulatory effects of barettin and involvement of the kinases CAMK1α and RIPK2. Immunopharmacology and Immunotoxicology 37:5, pages 458-464.
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Paul Bamborough. (2012) System-based drug discovery within the human kinome. Expert Opinion on Drug Discovery 7:11, pages 1053-1070.
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Articles from other publishers (19)

Renzo Rossi & Maurizio Ciofalo. (2019) Current Advances in the Synthesis and Biological Evaluation of Pharmacologically Relevant 1,2,4,5-Tetrasubstituted-1H-Imidazole Derivatives. Current Organic Chemistry 23:19, pages 2016-2101.
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Chieyeon Chough, Misuk Joung, Sunmin Lee, Jaemin Lee, Jong Hoon Kim & B. Moon Kim. (2018) Development of selective inhibitors for the treatment of rheumatoid arthritis: (R)-3-(3-(Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)-3-oxopropanenitrile as a JAK1-selective inhibitor. Bioorganic & Medicinal Chemistry 26:8, pages 1495-1510.
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Chieyeon Chough, Sunmin Lee, Misuk Joung, Jaemin Lee, Jong Hoon Kim & B. Moon Kim. (2018) Design, synthesis and evaluation of ( R )-3-(7-(methyl(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)amino)-5-azaspiro[2.4]heptan-5-yl)-3-oxopropanenitrile as a JAK1-selective inhibitor . MedChemComm 9:3, pages 477-489.
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Zeynep Yurtsever, Dhara A. Patel, Daniel L. Kober, Alvin Su, Chantel A. Miller, Arthur G. Romero, Michael J. Holtzman & Tom J. Brett. (2016) First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:11, pages 2335-2344.
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Mark J. Mondrinos, Linda C. Knight, Paul A. Kennedy, Jichuan Wu, Matthew Kauffman, Sandy T. Baker, Marla R. Wolfson & Laurie E. Kilpatrick. (2015) Biodistribution and Efficacy of Targeted Pulmonary Delivery of a Protein Kinase C- δ Inhibitory Peptide: Impact on Indirect Lung Injury . Journal of Pharmacology and Experimental Therapeutics 355:1, pages 86-98.
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Doriano Fabbro, Sandra W Cowan-Jacob & Henrik Moebitz. (2015) Ten things you should know about protein kinases: IUPHAR Review 14. British Journal of Pharmacology 172:11, pages 2675-2700.
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Christel J Menet, Oscar Mammoliti & Miriam López-Ramos. (2015) Progress toward JAK1-selective inhibitors. Future Medicinal Chemistry 7:2, pages 203-235.
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Sandra Marmiroli, Doriano Fabbro, Yoshihiko Miyata, Mariaelena Pierobon & Maria Ruzzene. (2015) Phosphorylation, Signaling, and Cancer: Targets and Targeting. BioMed Research International 2015, pages 1-3.
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Mathias Rask-Andersen, Jin Zhang, Doriano Fabbro & Helgi B. Schiöth. (2014) Advances in kinase targeting: current clinical use and clinical trials. Trends in Pharmacological Sciences 35:11, pages 604-620.
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Jean-Paul G. Seerden, Gabriela Leusink-Ionescu, Titia Woudenberg-Vrenken, Bas Dros, Grietje Molema, Jan A.A.M. Kamps & Richard M. Kellogg. (2014) Synthesis and structure–activity relationships of 4-fluorophenyl-imidazole p38α MAPK, CK1δ and JAK2 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 24:15, pages 3412-3418.
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Jean-Paul G. Seerden, Gabriela Leusink-Ionescu, Robin Leguijt, Catherine Saccavini, Edith Gelens, Bas Dros, Titia Woudenberg-Vrenken, Grietje Molema, Jan A.A.M. Kamps & Richard M. Kellogg. (2014) Syntheses and structure–activity relationships for some triazolyl p38α MAPK inhibitors. Bioorganic & Medicinal Chemistry Letters 24:5, pages 1352-1357.
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Oscar P. J. van Linden, Albert J. Kooistra, Rob Leurs, Iwan J. P. de Esch & Chris de Graaf. (2013) KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space. Journal of Medicinal Chemistry 57:2, pages 249-277.
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J. L. NORCLIFFE, E. ALVAREZ-RUIZ, J. J. MARTIN-PLAZA, P. G. STEEL & P. W. DENNY. (2013) The utility of yeast as a tool for cell-based, target-directed high-throughput screening. Parasitology 141:1, pages 8-16.
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Mark J. Mondrinos, Ting Zhang, Shuang Sun, Paul A. Kennedy, Devon J. King, Marla R. Wolfson, Linda C. Knight, Rosario Scalia & Laurie E. Kilpatrick. (2014) Pulmonary Endothelial Protein Kinase C-Delta (PKCδ) Regulates Neutrophil Migration in Acute Lung Inflammation. The American Journal of Pathology 184:1, pages 200-213.
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Dramane Lainé, Matthew Lucas, Francisco Lopez-Tapia & Stephen Lynch. 2013. Medicinal Chemistry Approaches to Personalized Medicine. Medicinal Chemistry Approaches to Personalized Medicine 255 288 .
Mark J. Mondrinos, Paul A. Kennedy, Melanie Lyons, Clifford S. Deutschman & Laurie E. Kilpatrick. (2013) Protein Kinase C and Acute Respiratory Distress Syndrome. Shock 39:6, pages 467-479.
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Stacy Van Epps, Bryan Fiamengo, Jeremy Edmunds, Anna Ericsson, Kristine Frank, Michael Friedman, Dawn George, Jonathan George, Eric Goedken, Brian Kotecki, Gloria Martinez, Philip Merta, Michael Morytko, Shashank Shekhar, Barbara Skinner, Kent Stewart, Jeffrey Voss, Grier Wallace, Lu Wang, Lu Wang & Neil Wishart. (2013) Design and synthesis of tricyclic cores for kinase inhibition. Bioorganic & Medicinal Chemistry Letters 23:3, pages 693-698.
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David H. Drewry, Paul Bamborough, Klaus Schneider & Gary K. Smith. 2011. Kinase Drug Discovery. Kinase Drug Discovery 1 53 .
Michal Brylinski & Jeffrey Skolnick. (2010) Cross-Reactivity Virtual Profiling of the Human Kinome by X-React KIN : A Chemical Systems Biology Approach . Molecular Pharmaceutics 7:6, pages 2324-2333.
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