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Expert Opinion on Drug Discovery Volume 6, 2011 - Issue 11
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The preclinical discovery of amyotrophic lateral sclerosis drugs

Marcie A Glicksman Brigham and Women's Hospital, Department of Neurology, 4th floor Partner's Research Building, 65 Landsdowne Street, Cambridge, MA 02139, [email protected]
Pages 1127-1138 | Published online: 25 Oct 2011

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Petra Dunkel, Christina LL Chai, Beáta Sperlágh, Paul B Huleatt & Péter Mátyus. (2012) Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis. Expert Opinion on Investigational Drugs 21:9, pages 1267-1308.
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Articles from other publishers (9)

Alyssa Walker & Daniel M. Czyz. (2023) Oh my gut! Is the microbial origin of neurodegenerative diseases real?. Infection and Immunity 91:10.
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Roohi Mohi-ud-din, Reyaz Hassan Mir, Abdul Jalil Shah, Saba Sabreen, Taha Umair Wani, Mubashir Hussain Masoodi, Esra Küpeli Akkol, Zulfiqar Ali Bhat & Haroon Khan. (2022) Plant-Derived Natural Compounds for the Treatment of Amyotrophic Lateral Sclerosis: An Update. Current Neuropharmacology 20:1, pages 179-193.
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Benjamin C Creekmore, Yi-Wei Chang & Edward B Lee. (2021) The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Aggregates. Journal of Neuropathology & Experimental Neurology 80:6, pages 514-529.
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Žiga Jakopin. (2020) 2-aminothiazoles in drug discovery: Privileged structures or toxicophores?. Chemico-Biological Interactions 330, pages 109244.
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Shunmoogum A. Patten, Dina Aggad, Jose Martinez, Elsa Tremblay, Janet Petrillo, Gary A.B. Armstrong, Alexandre La Fontaine, Claudia Maios, Meijiang Liao, Sorana Ciura, Xiao-Yan Wen, Victor Rafuse, Justin Ichida, Lorne Zinman, Jean-Pierre Julien, Edor Kabashi, Richard Robitaille, Lawrence Korngut, J. Alexander Parker & Pierre Drapeau. (2017) Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. JCI Insight 2:22.
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Vijay Kumar, Asimul Islam, Md. Imtaiyaz Hassan & Faizan Ahmad. (2016) Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning. European Journal of Medicinal Chemistry 121, pages 903-917.
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Takehisa Isobe, Norie Tooi, Norio Nakatsuji & Kazuhiro Aiba. (2015) Amyotrophic lateral sclerosis models derived from human embryonic stem cells with different superoxide dismutase 1 mutations exhibit differential drug responses. Stem Cell Research 15:3, pages 459-468.
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Allison S. Limpert & Nicholas D.P. Cosford. (2014) Translational enhancers of EAAT2: therapeutic implications for neurodegenerative disease. Journal of Clinical Investigation 124:3, pages 964-967.
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Allison S Limpert, Margrith E Mattmann & Nicholas D P Cosford. (2013) Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS). Beilstein Journal of Organic Chemistry 9, pages 717-732.
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