639
Views
24
CrossRef citations to date
0
Altmetric
Drug Discovery Case History

Ambroxol: a multifaceted molecule with additional therapeutic potentials in respiratory disorders of childhood

, , MD, &
Pages 1203-1214 | Published online: 25 Oct 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Dorotheea Cazan, Ludger Klimek, Annette Sperl, Manuel Plomer & Stephan Kölsch. (2018) Safety of ambroxol in the treatment of airway diseases in adult patients. Expert Opinion on Drug Safety 17:12, pages 1211-1224.
Read now

Articles from other publishers (23)

Tereza Uhlíková, Ivana Šlechtová, Jan Koucký, Patrik Kania, Jan Rohlíček & Štěpán Urban. (2023) Low Energy Vibrations and Crystalline Structure of Ambroxol Hydrochloride by THz Spectroscopy and DFT Calculations. ChemistrySelect 8:33.
Crossref
Avinash B. Gangurde, Suhas K. Khairnar & Vinod A. Bairagi. (2023) HYDROXYPROPYL CELLULOSE-CARBOPOL AND HYDROXYPROPYL CELLULOSE -NOVEON COMPOSITE MOUTH DISSOLVING FILMS OF AMBROXOL HYDROCHLORIDE. INDIAN DRUGS 60:08, pages 56-62.
Crossref
Zeguang Zheng, Kai Yang, Ni Liu, Xiuhua Fu, Huijie He, Hong Chen, Peijun Xu, Jing Wang, Maofeng Liu, Yuling Tang, Fengzi Zhao, Shufeng Xu, Xiaowei Yu, Jichang Han, Bo Yuan, Bin Jia, Guifen Pang, Yantong Shi, Min Kuang, Haiyan Shao, Hao Xiong, Jia He, Yuanyuan Pan & Rongchang Chen. (2023) Evaluation of safety and efficacy of inhaled ambroxol in hospitalized adult patients with mucopurulent sputum and expectoration difficulty. Frontiers in Medicine 10.
Crossref
Evita Balducci, Francesco Papi, Daniela Eloisa Capialbi & Linda Del Bino. (2023) Polysaccharides’ Structures and Functions in Biofilm Architecture of Antimicrobial-Resistant (AMR) Pathogens. International Journal of Molecular Sciences 24:4, pages 4030.
Crossref
Samantha Hughes, Maritza van Dop, Nikki Kolsters, David van de Klashorst, Anastasia Pogosova & Anouk M. Rijs. (2022) Using a Caenorhabditis elegans Parkinson’s Disease Model to Assess Disease Progression and Therapy Efficiency. Pharmaceuticals 15:5, pages 512.
Crossref
E. E. Lokshina & O. V. Zaytseva. (2022) Peculiarities of mucoactive therapy in pediatric practice. Meditsinskiy sovet = Medical Council:1, pages 97-104.
Crossref
Lore Herman, Stefaan C. De Smedt & Koen Raemdonck. (2022) Pulmonary surfactant as a versatile biomaterial to fight COVID-19. Journal of Controlled Release 342, pages 170-188.
Crossref
Shengguang Wang, Zhen Li, Xinyu Wang, Shiming Zhang, Peng Gao & Zuorong Shi. (2021) The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19. Frontiers in Pharmacology 12.
Crossref
Christin Walther, Kristin Döring & Michaela Schmidtke. (2020) Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts. BMC Complementary Medicine and Therapies 20:1.
Crossref
Anna Furgała-Wojas, Magdalena Kowalska, Alicja Nowaczyk, Łukasz Fijałkowski & Kinga Sałat. (2020) Comparison of Bromhexine and its Active Metabolite - Ambroxol as Potential Analgesics Reducing Oxaliplatin-induced Neuropathic Pain - Pharmacodynamic and Molecular Docking Studies. Current Drug Metabolism 21:7, pages 548-561.
Crossref
Pradeep Kumar. (2020) Co-aerosolized Pulmonary Surfactant and Ambroxol for COVID-19 ARDS Intervention: What Are We Waiting for?. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Rita M. Pinto, Filipa A. Soares, Salette Reis, Cláudia Nunes & Patrick Van Dijck. (2020) Innovative Strategies Toward the Disassembly of the EPS Matrix in Bacterial Biofilms. Frontiers in Microbiology 11.
Crossref
Shengke Li, Kit Ieng Kuok, Xia Ji, Anni Xu, Hang Yin, Jun Zheng, Huaping Tan & Ruibing Wang. (2020) Supramolecular Modulation of Antibacterial Activity of Ambroxol by Cucurbit[7]uril. ChemPlusChem 85:4, pages 679-683.
Crossref
Ahmad Kantar, Ludger Klimek, Dorotheea Cazan, Annette Sperl, Ulrike Sent & Margarida Mesquita. (2020) Ambroxol for the treatment of children with acute and chronic respiratory diseases: an overview of efficacy and safety. Multidisciplinary Respiratory Medicine 15.
Crossref
Sie Huey Lee, Desmond Heng, Jeanette W.P. Teo, Frederick K.Y. Toh & Reginald B.H. Tan. (2019) Inhaled mucoactive particles with tailored architecture for enhanced aerodynamicity, stability and efficacy. International Journal of Pharmaceutics 572, pages 118740.
Crossref
Peter Kardos, Kai-Michael Beeh, Ulrike Sent, Tobias Mueck, Heidemarie Gräter & Martin C. Michel. (2018) Characterization of differential patient profiles and therapeutic responses of pharmacy customers for four ambroxol formulations. BMC Pharmacology and Toxicology 19:1.
Crossref
J.D. Hull & R.A. Lyon. (2018) In vitro pharmacology of ambroxol: Potential serotonergic sites of action. Life Sciences 197, pages 67-72.
Crossref
Laura-Aline Martínez-Martínez, Luis-Fernando Pérez, Lizbeth-Teresa Becerril-Mendoza, Pedro Rodríguez-Henriquez, Omar-Eloy Muñoz, Gumaro Acosta, Luis H. Silveira, Angélica Vargas, María-Isabel Barrera-Villalpando & Manuel Martínez-Lavín. (2017) Ambroxol for fibromyalgia: one group pretest-posttest open-label pilot study. Clinical Rheumatology 36:8, pages 1879-1884.
Crossref
Manuel Plomer & Justus de Zeeuw. (2017) Mehr als ein Expektorans: neue wissenschaftliche Daten zu Ambroxol im Kontext der Behandlung bronchopulmonaler ErkrankungenMore than expectorant: new scientific data on ambroxol in the context of the treatment of bronchopulmonary diseases. MMW - Fortschritte der Medizin 159:S5, pages 22-33.
Crossref
Katsuyuki TakedaNobuaki MiyaharaShigeki MatsubaraChristian TaubeKenichi KitamuraAstushi HiranoMitsune TanimotoErwin W. Gelfand. (2016) Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation. Immune Network 16:3, pages 165.
Crossref
Yunhui Zhang, Yakun Fu, Jialin Yu, Qing Ai, Junshuai Li, Ningning Peng, Sijie Song, Yu He & Zhengli Wang. (2015) Synergy of ambroxol with vancomycin in elimination of catheter-related Staphylococcus epidermidis biofilm in vitro and in vivo. Journal of Infection and Chemotherapy 21:11, pages 808-815.
Crossref
Sie Huey Lee, Jeanette Teo, Desmond Heng, Yanli Zhao, Wai Kiong Ng, Hak-Kim Chan, Li Teng Tan & Reginald B.H. Tan. (2015) A novel inhaled multi-pronged attack against respiratory bacteria. European Journal of Pharmaceutical Sciences 70, pages 37-44.
Crossref
Frederic Tewes, Krzysztof J. Paluch, Lidia Tajber, Karan Gulati, Devesh Kalantri, Carsten Ehrhardt & Anne Marie Healy. (2013) Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 85:3, pages 604-613.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.