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Expert Opinion on Drug Discovery Volume 7, 2012 - Issue 3
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Aging biology: a new frontier for drug discovery

Ester VerdaguerDepartament de Biologia Cel·lular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
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Felix JunyentUnitat de Farmacologia i Farmacognòsia Facultat de Farmàcia, Institut de Biomedicina (IBUB), Centros de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat de Barcelona,Nucli Universitari de Pedralbes, 08028 Barcelona, Spain+934024531; +934035982; [email protected];Unitat de Bioquimica,Facultat de Medicina i Ciències de la Salut, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat Rovira i Virgili, C./St. Llorenç 21 43201 Reus (Tarragona), Spain
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Jaume FolchUnitat de Bioquimica,Facultat de Medicina i Ciències de la Salut, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat Rovira i Virgili, C./St. Llorenç 21 43201 Reus (Tarragona), Spain
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Carlos Beas-ZarateDepartamento de Biología Celular y Molecular, CUCBA, Universidad de Guadalajara. División de Neurociencias, Centro de Investigación Biomédica de Occidente, IMSS, Sierra Mojada 800, Col. Independencia, Guadalajara, Jalisco 44340, Mexico
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Carme AuladellDepartament de Biologia Cel·lular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
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Mercè PallàsUnitat de Farmacologia i Farmacognòsia Facultat de Farmàcia, Institut de Biomedicina (IBUB), Centros de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat de Barcelona,Nucli Universitari de Pedralbes, 08028 Barcelona, Spain+934024531; +934035982; [email protected]
&
Antoni CaminsUnitat de Farmacologia i Farmacognòsia Facultat de Farmàcia, Institut de Biomedicina (IBUB), Centros de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat de Barcelona,Nucli Universitari de Pedralbes, 08028 Barcelona, Spain+934024531; +934035982; [email protected]
, PhD show all
Pages 217-229 | Published online: 02 Feb 2012

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Siddhartha Dutta, Rima B Shah, Shubha Singhal, Sudeshna Banerjee Dutta, Sumit Bansal, Susmita Sinha & Mainul Haque. (2023) Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes. Drug Design, Development and Therapy 17, pages 1907-1932.
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Articles from other publishers (18)

David Della-Morte & Francesca Pacifici. (2023) Nature can still be the strongest help against aging and neurodegeneration: the sirtuins way. Neural Regeneration Research 18:6, pages 1271.
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Alexander M. Vaiserman & Oleh V. Lushchak. 2023. Anti-Aging Pharmacology. Anti-Aging Pharmacology 1 12 .
Michael D. Barnett & Jessica H. Helphrey. (2021) Who wants to live forever? Age cohort differences in attitudes toward life extension. Journal of Aging Studies 57, pages 100931.
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Akihiro Yamauchi, Takahiro Tone, Koji Sugimoto, Hong Seok Lim, Taiichi Kaku, Chihiro Tohda, Takayuki Shindo, Koji Tamada, Yoichi Mizukami & Eiichi Hirano. (2019) Porcine placental extract facilitates memory and learning in aged mice. Food Science & Nutrition 7:9, pages 2995-3005.
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Veronika Piskovatska, Nadiya Stefanyshyn, Kenneth B. Storey, Alexander M. Vaiserman & Oleh Lushchak. (2018) Metformin as a geroprotector: experimental and clinical evidence. Biogerontology 20:1, pages 33-48.
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Yaru Liang, Chang Liu, Maoyang Lu, Qiongye Dong, Zimu Wang, Zhuoran Wang, Wenxiang Xiong, Nannan Zhang, Jiawei Zhou, Qingfei Liu, Xiaowo Wang & Zhao Wang. (2018) Calorie restriction is the most reasonable anti-ageing intervention: a meta-analysis of survival curves. Scientific Reports 8:1.
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Alexander Vaiserman & Oleh Lushchak. 2018. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Yaru Liang & Zhao Wang. 2018. Aging and Aging-Related Diseases. Aging and Aging-Related Diseases 267 282 .
Alexander Vaiserman & Oleh Lushchak. (2017) Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives. Journal of Translational Medicine 15:1.
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A.M. Vaiserman. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 349 378 .
Alexander M. Vaiserman, Oleh V. Lushchak & Alexander K. Koliada. (2016) Anti-aging pharmacology: Promises and pitfalls. Ageing Research Reviews 31, pages 9-35.
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Lijun Wang, Yuk Man Li, Lin Lei, Yuwei Liu, Xiaobo Wang, Ka Ying Ma, Chengnan Zhang, Hanyue Zhu, Yimin Zhao & Zhen-Yu Chen. (2016) Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster. Experimental Gerontology 82, pages 95-103.
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Alexander M. Vaiserman & Francesco Marotta. (2016) Longevity-Promoting Pharmaceuticals: Is it a Time for Implementation?. Trends in Pharmacological Sciences 37:5, pages 331-333.
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Roman M. Stilling, Eva Benito, Jonas Barth, Michael Gertig, Vincenzo Capece, Susanne Burckhardt, Stefan Bonn & Andre Fischer. (2014) De-regulation of gene expression and alternative splicing affects distinct cellular pathways in the aging hippocampus. Frontiers in Cellular Neuroscience 8.
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Vattoly J. Majo, Norman R. Simpson, Jaya Prabhakaran, J. John Mann & J. S. Dileep Kumar. (2014) Radiosynthesis of [ 18 F]ATPFU: a potential PET ligand for mTOR . Journal of Labelled Compounds and Radiopharmaceuticals 57:13, pages 705-709.
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Jan Kevin Schluesener & Hermann Schluesener. (2014) Plant polyphenols in the treatment of age-associated diseases: Revealing the pleiotropic effects of icariin by network analysis. Molecular Nutrition & Food Research 58:1, pages 49-60.
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Koji Tomobe, Tatsuo Shinozuka, Tsuyoshi Kawashima, Yoshie Kawashima-Ohya & Yasuyuki Nomura. (2013) Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8. Archives of Gerontology and Geriatrics 57:3, pages 417-422.
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Sang Yoon Choi, Young Ock Kim, Dongwook Son, Jongseok Lee, Sanghee Kim, Hocheol Kim, SunYeou Kim & Jinyoung Hur. (2012) 3-[2-(3,5-Dimethoxyphenyl)vinyl]furan protects hippocampal neurons against ischemic damage. Brain Research 1472, pages 32-37.
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