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Boron as a platform for new drug design

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Pages 1017-1027 | Published online: 05 Sep 2012

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Mothana K. Al-Omari, Mai Elaarag, Raed M. Al-Zoubi, Ahmad R. Al-Qudimat, Ayman A. Zarour, Enas A. Al-Hurani, Zainab E. Fares, Leena M. Alkharraz, Mohanad Shkoor, Abdulilah D. Bani-Yaseen, Omar M. Aboumarzouk, Aksam Yassin & Abdulla A. Al-Ansari. (2023) Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Shazid Md Sharker. (2019) Hexagonal Boron Nitrides (White Graphene): A Promising Method for Cancer Drug Delivery. International Journal of Nanomedicine 14, pages 9983-9993.
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Alessio Nocentini, Claudiu T. Supuran & Jean-Yves Winum. (2018) Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018). Expert Opinion on Therapeutic Patents 28:6, pages 493-504.
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Marvin A Soriano-Ursúa, Bhaskar C Das & José G Trujillo-Ferrara. (2014) Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy. Expert Opinion on Therapeutic Patents 24:5, pages 485-500.
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Stephen L. Bearne. (2023) Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase. Philosophical Transactions of the Royal Society B: Biological Sciences 378:1871.
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Anja Haveric, Sanin Haveric, Maida Hadzic, Jasmin Ezic, Tamara Cetković & Borivoj Galic. (2023) Moderate Toxicity of Potential Boron-containing Therapeutic, Dipotassium-trioxohydroxytetrafl uorotriborate -K2(B3O3F4OH) in Rats and Mice. Brazilian Journal of Pharmaceutical Sciences 59.
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V. V. Belakhov. (2023) Polyfunctional Drugs: Search, Development, Use in Medical Practice, and Environmental Aspects of Preparation and Application (A Review). Russian Journal of General Chemistry 92:13, pages 3030-3055.
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Jocelyn M. Macho, Riley M. Blue, Hsiau-Wei Lee & John B. MacMillan. (2022) Boron NMR as a Method to Screen Natural Product Libraries for B-Containing Compounds. Organic Letters 24:17, pages 3161-3166.
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Amar Nath Sharma, Lia Grandinetti, Erin R. Johnson, Martin St. Maurice & Stephen L. Bearne. (2020) Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center. Biochemistry 59:33, pages 3026-3037.
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Ahmet Kilic, Ahmet Savci, Yusuf Alan & Levent Beyazsakal. (2020) The synthesis of novel boronate esters and N-Heterocyclic carbene (NHC)-stabilized boronate esters: Spectroscopy, antimicrobial and antioxidant studies. Journal of Organometallic Chemistry 917, pages 121268.
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Jan Nekvinda, Daria Różycka, Sebastian Rykowski, Eliza Wyszko, Agnieszka Fedoruk-Wyszomirska, Dorota Gurda, Marta Orlicka-Płocka, Małgorzata Giel-Pietraszuk, Agnieszka Kiliszek, Wojciech Rypniewski, Rafał Bachorz, Jakub Wojcieszak, Bohumir Grüner & Agnieszka B. Olejniczak. (2020) Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability. Bioorganic Chemistry 94, pages 103432.
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Kenneth Arrington, Gregg A. Barcan, Nicholas A. Calandra, Greg A. Erickson, Ling Li, Li Liu, Mark G. Nilson, Iulia I. Strambeanu, Kelsey F. VanGelder, John L. Woodard, Shiping Xie, C. Liana Allen, John A. Kowalski & David C. Leitch. (2018) Convergent Synthesis of the NS5B Inhibitor GSK8175 Enabled by Transition Metal Catalysis. The Journal of Organic Chemistry 84:8, pages 4680-4694.
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Jonathan C. Axtell, Liban M. A. Saleh, Elaine A. Qian, Alex I. Wixtrom & Alexander M. Spokoyny. (2018) Synthesis and Applications of Perfunctionalized Boron Clusters. Inorganic Chemistry 57:5, pages 2333-2350.
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Hyun Seung Ban & Hiroyuki Nakamura. (2015) Boron-Based Drug Design. The Chemical Record 15:3, pages 616-635.
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A N Tevyashova, E N Olsufyeva & M N Preobrazhenskaya. (2015) Design of dual action antibiotics as an approach to search for new promising drugs. Russian Chemical Reviews 84:1, pages 61-97.
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Weimin Ye, Wenbo Li & Junliang Zhang. (2014) A metal-free dyotropic-like rearrangement of 2-oxa allylic alcohols in the presence of organoboronic acids. Chem. Commun. 50:69, pages 9879-9882.
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Matthew R. Aronoff, Brett VanVeller & Ronald T. Raines. (2013) Detection of Boronic Acids through Excited-State Intramolecular Proton-Transfer Fluorescence. Organic Letters 15:20, pages 5382-5385.
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Bhaskar C DasPritam Thapa, Radha Karki, Caroline Schinke, Sasmita Das, Suman Kambhampati, Sushanta K Banerjee, Peter Van Veldhuizen, Amit Verma, Louis M Weiss & Todd Evans. (2013) Boron chemicals in diagnosis and therapeutics. Future Medicinal Chemistry 5:6, pages 653-676.
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