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Novel approaches to the development of tyrosine kinase inhibitors and their role in the fight against cancer

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Abdelbaset Mohamed Elasbali, Waleed Abu Al-Soud, Elyasa Mustafa Elfaki, Hamad H. Alanazi, Bandar Alharbi, Salem Hussain Alharethi, Khalid Anwer, Taj Mohammad & Md. Imtaiyaz Hassan. (2023) Identification of novel c-Kit inhibitors from natural sources using virtual screening and molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
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Debmalya Das Gupta, Saurov Mahanta, Tanzim Nishad Ullah, Sanjib Kumar Das, Anjini Bellai, Hui Tag & Pallabi Kalita Hui. (2023) Identification of phytocompounds from Paris polyphylla Smith as potential inhibitors for HER2 & VEGFR2 cancer genes using molecular docking and molecular dynamics simulation studies. Vegetos.
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Jan Petr. (2023) Determination of Tyrosine Kinase Inhibitors via Capillary Electrophoresis with Tandem Mass Spectrometry and Online Stacking Preconcentration. Pharmaceuticals 16:2, pages 186.
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Chenglong Chen, Qianyu Shi, Jiuhui Xu, Tingting Ren, Yi Huang & Wei Guo. (2022) Current progress and open challenges for applying tyrosine kinase inhibitors in osteosarcoma. Cell Death Discovery 8:1.
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Pooja Gupta, Tavneet Kaur Makkar, Lavisha Goel & Monika Pahuja. (2022) Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity. Immunologic Research 70:6, pages 725-741.
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Dipayan Paul, Saurov Mahanta, Hui Tag, Sanjib Kumar Das, Debmalya Das Gupta, Bhaben Tanti, Rajendran Ananthan, Ranjan Das, Sanjay Jambhulkar & Pallabi Kalita Hui. (2021) Identification of tyrosine kinase inhibitors from Panax bipinnatifidus and Panax pseudoginseng for RTK—HER2 and VEGFR2 receptors, by in silico approach. Molecular Diversity 26:4, pages 1933-1955.
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Ashish Shah, Chhagan Patel, Ghanshaym Parmar, Ashish Patel & Manav Jain. (2022) A Concise Review on Tyrosine Kinase Targeted Cancer Therapy. Current Drug Therapy 17:2, pages 96-107.
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Seungbeom Lee, Jisu Kim, Jeyun Jo, Jae Won Chang, Jaehoon Sim & Hwayoung Yun. (2021) Recent advances in development of hetero-bivalent kinase inhibitors. European Journal of Medicinal Chemistry 216, pages 113318.
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Liling Huang, Shiyu Jiang & Yuankai Shi. (2020) Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001–2020). Journal of Hematology & Oncology 13:1.
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Min-Hee Kim, Tae Hyeong Lee, Jin Soo Lee, Dong-Jun Lim & Peter Chang-Whan Lee. (2020) Hif-1α Inhibitors Could Successfully Inhibit the Progression of Differentiated Thyroid Cancer in Vitro. Pharmaceuticals 13:9, pages 208.
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Imane Naboulsi, Aziz Aboulmouhajir, Lamfeddal Kouisni, Faouzi Bekkaoui & Abdelaziz Yasri. (2018) Combining a QSAR Approach and Structural Analysis to Derive an SAR Map of Lyn Kinase Inhibition. Molecules 23:12, pages 3271.
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Ning Li, Binrong Yao, Chunhua Wang, Qingguo Meng & Guige Hou. (2017) Synthesis, crystal structure and activity evaluation of novel 3,4-dihydro-1-benzoxepin-5(2 H )-one derivatives as protein–tyrosine kinase (PTK) inhibitors . Acta Crystallographica Section C Structural Chemistry 73:11, pages 1003-1009.
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Simona Turco, Isabelle Tardy, Peter Frinking, Hessel Wijkstra & Massimo Mischi. (2017) On the validity of the first-pass binding model for quantitative ultrasound molecular imaging: Comparison between BR55 and Sonovue. On the validity of the first-pass binding model for quantitative ultrasound molecular imaging: Comparison between BR55 and Sonovue.
Bing Liu, XinPing Huang, YunLong Hu, TingTing Chen, BoYa Peng, NingNing Gao, ZhenChao Jin, TieLiu Jia, Na Zhang, ZhuLin Wang & GuangYi Jin. (2016) Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer. Oncotarget 7:36, pages 58038-58050.
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Simona Turco, Ahmed El Kaffas, Jianhua Zhou, Hessel Wijkstra, Juergen K Willmann & Massimo Mischi. (2016) Quantitative ultrasound molecular imaging for antiangiogenic therapy monitoring. Quantitative ultrasound molecular imaging for antiangiogenic therapy monitoring.
Jin Zhang, Xiangdong Jiang, Yingnan Jiang, Mingrui Guo, Shouyue Zhang, Jingjing Li, Jun He, Jie Liu, Jinhui Wang & Liang Ouyang. (2016) Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs. European Journal of Medicinal Chemistry 108, pages 495-504.
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Chaochao Xu, Wulan Li, Peihong Qiu, Yiqun Xia, Xiaojing Du, Fen Wang, Lailai Shen, Qiuxiang Chen, Yunjie Zhao, Rong Jin, Jianzhang Wu, Guang Liang & Xiaokun Li. (2015) The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. Anti-Cancer Drugs 26:4, pages 379-387.
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Maria J. Pineda de las Infantas, Sara Torres-Rusillo, Juan Diego Unciti-Broceta, Pablo Fernandez-Rubio, Maria Angelica Luque-GonzalezMiguel A. Gallo, Asier Unciti-Broceta, Ignacio J. Molina & Juan J. Diaz-Mochon. (2015) Synthesis of 6,8,9 poly-substituted purine analogue libraries as pro-apoptotic inducers of human leukemic lymphocytes and DAPK-1 inhibitors. Organic & Biomolecular Chemistry 13:18, pages 5224-5234.
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