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Status of drug development for the prevention and treatment of osteoporosis

, MD DMSci (Professor, Director of Research Center of Ageing and Osteoporosis) , &

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Johann Lechner, Tatjana Rudi & Volker von Baehr. (2018) Osteoimmunology of tumor necrosis factor-alpha, IL-6, and RANTES/CCL5: a review of known and poorly understood inflammatory patterns in osteonecrosis. Clinical, Cosmetic and Investigational Dentistry 10, pages 251-262.
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Luigi Gennari, Stefano Rotatori, Simone Bianciardi, Stefano Gonnelli, Ranuccio Nuti & Daniela Merlotti. (2015) Appropriate models for novel osteoporosis drug discovery and future perspectives. Expert Opinion on Drug Discovery 10:11, pages 1201-1216.
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Maria Felicia Faienza, Vincenza Luce, Antonella Lonero, Annamaria Ventura, Graziana Colaianni, Silvia Colucci, Luciano Cavallo, Maria Grano & Giacomina Brunetti. (2014) Treatment of osteoporosis in children with glucocorticoid-treated diseases. Expert Review of Endocrinology & Metabolism 9:5, pages 525-534.
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Articles from other publishers (13)

Hanlu Ye, Ke Wang & Kai Li. (2023) Anti-osteoporosis Effect of Cynaropicrin against Ovariectomy-induced Osteoporosis in Rats. Pharmacognosy Magazine 19:2, pages 448-460.
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Mihyang Kim & Mihwa Park. (2022) The Brown Algae Ishige sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis through Downregulation of NFATc1/c-Fos. Nutrients 14:9, pages 1683.
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Yushu Huang, Yukang Li & Sean X. Leng. 2022. Osteosarcopenia. Osteosarcopenia 91 116 .
Min Cui, Na Zhang, Gang Zhang, Lei Han & Ling Zhi Yu. (2021) Investigation of Intravenous Zoledronic Acid Therapy on Circulating Lymphocyte Subpopulation in Patients with Primary Osteoporosis: A Pilot Study. Current Therapeutic Research 94, pages 100634.
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Luna Ge, Yazhou Cui, Baoyan Liu, Xiaoli Yin, Jingxiang Pang & Jinxiang Han. (2019) ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis. Molecular Medicine Reports.
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M. J. Rothmann, P. R. Jakobsen, C. M. Jensen, A. P. Hermann, A. C Smith & J. Clemensen. (2018) Experiences of being diagnosed with osteoporosis: a meta-synthesis. Archives of Osteoporosis 13:1.
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Harshika Awasthi, Dayanandan Mani, Divya Singh & Atul Gupta. (2018) The underlying pathophysiology and therapeutic approaches for osteoporosis. Medicinal Research Reviews 38:6, pages 2024-2057.
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Titi Liu, Shihua Ding, Dan Yin, Xiangdan Cuan, Chuanqi Xie, Huanhuan Xu, Xuanjun Wang & Jun Sheng. (2017) Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro. Frontiers in Pharmacology 8.
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Natasha M. Appelman-Dijkstra & Socrates E. Papapoulos. (2016) From disease to treatment: from rare skeletal disorders to treatments for osteoporosis. Endocrine 52:3, pages 414-426.
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Jung Hee Joo, Jeong-Eun Huh, Jee Hyun Lee, Doo Ri Park, Yoonji Lee, Seul Gee Lee, Sun Choi, Hwa Jeong Lee, Seong-Won Song, Yongmi Jeong, Ja-Il Goo, Yongseok Choi, Hye Kyung Baek, Sun Shin Yi, Soo Jin Park, Ji Eun Lee, Sae Kwang Ku, Won Jae Lee, Kee-In Lee, Soo Young Lee & Yun Soo Bae. (2016) A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase. Scientific Reports 6:1.
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Andrés Felipe Posada, Hernán Darío Aguirre, Julio Cesar García Casallas, Jhon Darío Lodoño Patiño & Rafael Valle Oñate. (2016) New therapies in osteoporosis. Revista Colombiana de Reumatología (English Edition) 23:1, pages 34-43.
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Andrés Felipe Posada, Hernán Darío Aguirre, Julio Cesar García Casallas, Jhon Darío Lodoño Patiño & Rafael Valle Oñate. (2016) Nuevas terapias en osteoporosis. Revista Colombiana de Reumatología 23:1, pages 34-43.
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Sujit Kootala, Dmitri Ossipov, Jeroen JJP van den Beucken, Sander Leeuwenburgh & Jöns Hilborn. (2015) Bisphosphonate-functionalized hyaluronic acid showing selective affinity for osteoclasts as a potential treatment for osteoporosis. Biomaterials Science 3:8, pages 1197-1207.
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