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Expert Opinion on Drug Discovery Volume 10, 2015 - Issue 10
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Review

Activity landscape of DNA methyltransferase inhibitors bridges chemoinformatics with epigenetic drug discovery

J Jesús NavejaUniversidad Nacional Autónoma de México, Departamento de Farmacia, Facultad de Química, Avenida Universidad 3000, Mexico City, D.F. 04510, México+5255 5622 3899 Ext. 44458; [email protected]; [email protected];Universidad Nacional Autónoma de México, PECEM, Facultad de Medicina, Avenida Universidad 3000, Mexico City, D.F. 04510, México
&
José L Medina-FrancoUniversidad Nacional Autónoma de México, Departamento de Farmacia, Facultad de Química, Avenida Universidad 3000, Mexico City, D.F. 04510, México+5255 5622 3899 Ext. 44458; [email protected]; [email protected]
Pages 1059-1070 | Published online: 01 Aug 2015

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Martin Vogt. (2018) Progress with modeling activity landscapes in drug discovery. Expert Opinion on Drug Discovery 13:7, pages 605-615.
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Marzieh Ramezani Farani, Maryam Sarlak, Amir Gholami, Maryam Azaraian, Maryam Moradi Binabaj, Sareh Kakavandi, Murtaza M. Tambuwala, Afshin Taheriazam, Mehrdad Hashemi & Sorayya Ghasemi. (2023) Epigenetic drugs as new emerging therapeutics: What is the scale's orientation of application and challenges?. Pathology - Research and Practice 248, pages 154688.
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Marisa G. Santibáñez‐Morán & José L. Medina‐Franco. (2021) The Acid/Base Characterization of Molecules with Epigenetic Activity. ChemMedChem 16:11, pages 1745-1754.
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Fidele Ntie-Kang, Berin Karaman Mayack, Sergio Valente & Cecilia Battistelli. (2021) Editorial: Natural Product Epigenetic Modulators and Inhibitors. Frontiers in Pharmacology 12.
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Zoe Sessions, Norberto Sánchez-Cruz, Fernando D. Prieto-Martínez, Vinicius M. Alves, Hudson P. SantosJr.Jr., Eugene Muratov, Alexander Tropsha & José L. Medina-Franco. (2020) Recent progress on cheminformatics approaches to epigenetic drug discovery. Drug Discovery Today 25:12, pages 2268-2276.
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T.K. Shameera Ahamed & K. Muraleedharan. (2020) Towards a systematic analysis of structure-activity relationships of 5-LOX inhibitors through activity landscape and chemotype enrichment. Chemometrics and Intelligent Laboratory Systems 207, pages 104188.
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Wen Liu & Bing Luo. (2020) The impact of EBV on the epigenetics of gastric carcinoma. Future Virology 15:3, pages 183-193.
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Kenneth Lundstrom. (2019) Epigenetics, Nutrition, Disease and Drug Development. Current Drug Discovery Technologies 16:4, pages 386-391.
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Samuel Egieyeh, Sarel F. Malan & Alan Christoffels. (2019) Cheminformatics techniques in antimalarial drug discovery and development from natural products 1: basic concepts. Physical Sciences Reviews 4:7.
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J. Jesús Naveja, C. Iluhí Oviedo-Osornio, Nicole N. Trujillo-Minero & José L. Medina-Franco. (2017) Chemoinformatics: a perspective from an academic setting in Latin America. Molecular Diversity 22:1, pages 247-258.
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J. Jesús Naveja & José L. Medina-Franco. (2018) Insights from pharmacological similarity of epigenetic targets in epipolypharmacology. Drug Discovery Today 23:1, pages 141-150.
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J. Jesús Naveja, C. Iluhí Oviedo-Osornio & José L. Medina-Franco. 2018.
Mariana González-Medina, Oscar Méndez-Lucio & José L. Medina-Franco. (2017) Activity Landscape Plotter: A Web-Based Application for the Analysis of Structure–Activity Relationships. Journal of Chemical Information and Modeling 57:3, pages 397-402.
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Fernanda I. Saldívar-González, J. Jesús Naveja, Oscar Palomino-Hernández & José L. Medina-Franco. (2017) Getting SMARt in drug discovery: chemoinformatics approaches for mining structure–multiple activity relationships. RSC Advances 7:2, pages 632-641.
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Mario Omar García-Sánchez, Maykel Cruz-Monteagudo & José L. Medina-Franco. 2017. Advances in QSAR Modeling. Advances in QSAR Modeling 303 338 .
J. Jesús Naveja, Francisco Cortés-Benítez, Eugene Bratoeff & José L. Medina-Franco. (2016) Activity landscape analysis of novel 5$$\upalpha $$-reductase inhibitors. Molecular Diversity 20:3, pages 771-780.
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Petra Hudler. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 9 .
Eli Fernández-de Gortari & José L. Medina-Franco. (2015) Epigenetic relevant chemical space: a chemoinformatic characterization of inhibitors of DNA methyltransferases. RSC Advances 5:106, pages 87465-87476.
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J. Jesús Naveja & José L. Medina-Franco. (2015) Activity landscape sweeping: insights into the mechanism of inhibition and optimization of DNMT1 inhibitors. RSC Advances 5:78, pages 63882-63895.
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