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Expert Opinion on Drug Discovery Volume 10, 2015 - Issue 2
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Review

Genomics and epigenomics in novel schizophrenia drug discovery: translating animal models to clinical research and back

Marta BosiaIRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Via Stamira d’Ancona 20, 20127 Milano, Italy+390 226 433 218; +390 226 433 265; [email protected];Institute for Advanced Study, Center for Neurocognition and Theoretical Syntax, Pavia, Italy
,
Alessandro PigoniIRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Via Stamira d’Ancona 20, 20127 Milano, Italy+390 226 433 218; +390 226 433 265; [email protected];Università Vita-Salute San Raffaele, Milan, Italy
&
Roberto CavallaroIRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Via Stamira d’Ancona 20, 20127 Milano, Italy+390 226 433 218; +390 226 433 265; [email protected]
Pages 125-139 | Published online: 25 Oct 2014

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Xuemei Liao, Hui Ye & Tianmei Si. (2021) A Review of Switching Strategies for Patients with Schizophrenia Comorbid with Metabolic Syndrome or Metabolic Abnormalities. Neuropsychiatric Disease and Treatment 17, pages 453-469.
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Articles from other publishers (12)

Joana Viana, Nick Wildman, Eilis Hannon, Audrey Farbos, Paul O’ Neill, Karen Moore, Ronny van Aerle, Greg Paull, Eduarda Santos & Jonathan Mill. (2020) Clozapine-induced transcriptional changes in the zebrafish brain. npj Schizophrenia 6:1.
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Yidan Sun, Wei Zhou, Luan Chen, Cong Huai, Hailiang Huang, Lin He & Shengying Qin. (2019) Omics in schizophrenia: current progress and future directions of antipsychotic treatments. Journal of Bio-X Research 2:4, pages 145-152.
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Marta Bosia, Mariachiara Buonocore, Margherita Bechi, Liliana-Mihaela Stere, Maria Paola Silvestri, Emanuela Inguscio, Marco Spangaro, Federica Cocchi, Laura Bianchi, Carmelo Guglielmino & Roberto Cavallaro. (2019) Schizophrenia, cannabis use and Catechol-O-Methyltransferase (COMT): Modeling the interplay on cognition. Progress in Neuro-Psychopharmacology and Biological Psychiatry 92, pages 363-368.
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A. E. Gareeva & E. K. Khusnutdinova. (2018) Schizophrenia Genetics. Russian Journal of Genetics 54:6, pages 593-603.
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Giuseppe Delvecchio, Alessandro Pigoni, Cinzia Perlini, Marco Barillari, Mirella Ruggeri, Alfredo Carlo Altamura, Marcella Bellani & Paolo Brambilla. (2017) Sexual dimorphism of the planum temporale in schizophrenia: A MRI study. Australian & New Zealand Journal of Psychiatry 51:10, pages 1010-1019.
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Qi Lai, Yin-Hui Xu, Qiang Chen, Liang Tang, An-Gui Li, Li-Fei Zhang, Chun-Fang Zhang, Jian-Fei Song & Zhen-Zong Du. (2017) The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC in vitro and vivo . Oncotarget 8:35, pages 59301-59311.
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M. V. Alfimova, N. V. Kondratiev & V. E. Golimbet. (2017) Results and promises of genetics of cognitive impairment in schizophrenia: epigenetic approaches. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 117:2, pages 130.
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T. V. Lezheiko & M. V. Alfimova. (2017) Epigenetic research of cognitive deficit in schizophrenia: some methodological considerations. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 117:10, pages 76.
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Walter H. MoosDouglas V. FallerDavid N. HarppIphigenia KanaraJulie PernokasWhitney R. PowersKosta Steliou. (2016) Microbiota and Neurological Disorders: A Gut Feeling. BioResearch Open Access 5:1, pages 137-145.
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Jacob Peedicayil. (2016) Preclinical epigenetic models for screening epigenetic drugs for schizophrenia. Journal of Pharmacological and Toxicological Methods 77, pages 1-5.
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Marta Bosia, Alessandro Pigoni, Laura Zagato, Lino Merlino, Nunzia Casamassima, Cristina Lorenzi, Adele Pirovano, Enrico Smeraldi, Paolo Manunta & Roberto Cavallaro. (2016) ADDing a piece to the puzzle of cognition in schizophrenia. European Journal of Medical Genetics 59:1, pages 26-31.
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Melkaye G. Melka, Christina A. Castellani, Richard O’Reilly & Shiva M. Singh. (2015) Insights into the origin of DNA methylation differences between monozygotic twins discordant for schizophrenia. Journal of Molecular Psychiatry 3:1.
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