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Expert Opinion on Drug Discovery Volume 3, 2008 - Issue 8
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Reviews

Advantages and application of label-free detection assays in drug screening

Brian T Cunningham Associate Professor of Electrical and Computer Engineering University of Illinois at Urbana-Champaign, Micro and Nanotechnology Laboratory, 208 North Wright Street, Urbana, IL 61801, USA +1 217 265 6291; +1 217 244 6375; [email protected]
&
Lance G Laing Director of Application Development SRU Biosystems, 14A Gill Street, Woburn, MA 01801, USA
Pages 891-901 | Published online: 16 Jul 2008

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Kenneth Lundstrom. (2017) Cell-impedance-based label-free technology for the identification of new drugs. Expert Opinion on Drug Discovery 12:4, pages 335-343.
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Reena Halai & Matthew A Cooper. (2012) Using label-free screening technology to improve efficiency in drug discovery. Expert Opinion on Drug Discovery 7:2, pages 123-131.
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Sen Xu & Raj Mutharasan. (2009) Cantilever biosensors in drug discovery. Expert Opinion on Drug Discovery 4:12, pages 1237-1251.
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Lakshmi B. V. S. Garimella, Tarun K. Dhiman, Rahul Kumar, Avinash K. Singh & Pratima R. Solanki. (2020) One-Step Synthesized ZnO np-Based Optical Sensors for Detection of Aldicarb via a Photoinduced Electron Transfer Route. ACS Omega 5:6, pages 2552-2560.
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Patricia M.K. Mathabe, Zinash A. Belay, Thulile Ndlovu & Oluwafemi J. Caleb. (2020) Progress in proteomic profiling of horticultural commodities during postharvest handling and storage: A review. Scientia Horticulturae 261, pages 108996.
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Ruitao Liu, Xiongying Ye & Tianhong Cui. (2020) Recent Progress of Biomarker Detection Sensors. Research 2020.
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Nurul Hazwani Daud, Siti Nurbaya Oslan, Thean Chor Leow & Abu Bakar Salleh. (2019) Development of an enzyme-based fiber optic biosensor for detection of haloalkanes. Sensor Review 39:6, pages 810-818.
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Enxiao Luan, Han Yun, Minglei Ma, Daniel M. Ratner, Karen C. Cheung & Lukas Chrostowski. (2019) Label-free biosensing with a multi-box sub-wavelength phase-shifted Bragg grating waveguide. Biomedical Optics Express 10:9, pages 4825.
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Enxiao Luan, Hossam Shoman, Daniel Ratner, Karen Cheung & Lukas Chrostowski. (2018) Silicon Photonic Biosensors Using Label-Free Detection. Sensors 18:10, pages 3519.
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Jose Muñoz, Raquel Montes & Mireia Baeza. (2017) Trends in electrochemical impedance spectroscopy involving nanocomposite transducers: Characterization, architecture surface and bio-sensing. TrAC Trends in Analytical Chemistry 97, pages 201-215.
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Alexander L. Breeze, Richard A. Ward & Jon Winter. 2016. Fragment-based Drug Discovery Lessons and Outlook. Fragment-based Drug Discovery Lessons and Outlook 391 424 .
Shuwen Sun, Benjamin C. Buer, E. Neil G. Marsh & Robert T. Kennedy. (2016) A label-free Sirtuin 1 assay based on droplet-electrospray ionization mass spectrometry. Analytical Methods 8:17, pages 3458-3465.
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Shuwen Sun & Robert T. Kennedy. (2014) Droplet Electrospray Ionization Mass Spectrometry for High Throughput Screening for Enzyme Inhibitors. Analytical Chemistry 86:18, pages 9309-9314.
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Bahareh Honarparvar, Thavendran Govender, Glenn E. M. Maguire, Mahmoud E. S. Soliman & Hendrik G. Kruger. (2013) Integrated Approach to Structure-Based Enzymatic Drug Design: Molecular Modeling, Spectroscopy, and Experimental Bioactivity. Chemical Reviews 114:1, pages 493-537.
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Dustin Gallegos, Kenneth D. Long, Hojeong Yu, Peter P. Clark, Yixiao Lin, Sherine George, Pabitra Nath & Brian T. Cunningham. (2013) Label-free biodetection using a smartphone. Lab on a Chip 13:11, pages 2124.
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Shuwen Sun, Thomas R. Slaney & Robert T. Kennedy. (2012) Label Free Screening of Enzyme Inhibitors at Femtomole Scale Using Segmented Flow Electrospray Ionization Mass Spectrometry. Analytical Chemistry 84:13, pages 5794-5800.
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Richard A. WardClaire BrassingtonAlexander L. BreezeAlessandro CaputoSusan CritchlowGareth DaviesLouise GoodwinGiles HassallRyan GreenwoodGeoffrey A. HoldgateMichael MrosekRichard A. NormanStuart PearsonJonathan TartJulie A. TuckerMartin VogtherrDavid WhittakerJonathan WingfieldJon WinterKevin Hudson. (2012) Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation. Journal of Medicinal Chemistry 55:7, pages 3285-3306.
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Johannes Ottl. 2011. Label‐Free Technologies for Drug Discovery. Label‐Free Technologies for Drug Discovery 155 169 .
Zoran Rankovic, Craig Jamieson & Richard Morphy. 2010. Lead Generation Approaches in Drug Discovery. Lead Generation Approaches in Drug Discovery 21 71 .
Rebecca L. Rich & David G. Myszka. (2009) Grading the commercial optical biosensor literature-Class of 2008: ‘The Mighty Binders’. Journal of Molecular Recognition 23:1, pages 1-64.
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