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Review

Integrins and extracellular matrix: a novel mechanism of multidrug resistance

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Pages 449-459 | Published online: 10 Jan 2014

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Prarthana Gopinath, Aparna Natarajan, Amritha Sathyanarayanan, Sridevi Veluswami & Gopal Gopisetty. (2022) The multifaceted role of Matricellular Proteins in health and cancer, as biomarkers and therapeutic targets. Gene 815, pages 146137.
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Jin-hai Tian, Shi-hai Liu, Chuan-yang Yu, Li-gang Wu & Li-bin Wang. (2021) The Role of Non-Coding RNAs in Breast Cancer Drug Resistance. Frontiers in Oncology 11.
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Yuejiao Huang, Yuchan Wang, Jie Tang, Shiyi Qin, Xianjuan Shen, Song He & Shaoqing Ju. (2021) CAM-DR: Mechanisms, Roles and Clinical Application in Tumors. Frontiers in Cell and Developmental Biology 9.
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Eleanor C. FiedlerMichael T. Hemann. (2019) Aiding and Abetting: How the Tumor Microenvironment Protects Cancer from Chemotherapy. Annual Review of Cancer Biology 3:1, pages 409-428.
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Luwei Wei, Fuqiang Yin, Changxian Chen & Li Li. (2019) Expression of integrin α‑6 is associated with multi drug resistance and prognosis in ovarian cancer. Oncology Letters.
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Elizabeth Ntantie, Michaela J. Allen, Jerrine Fletcher, Augustine T. Nkembo, Nazarius S. Lamango & Offiong F. Ikpatt. (2018) Suppression of focal adhesion formation may account for the suppression of cell migration, invasion and growth of non-small cell lung cancer cells following treatment with polyisoprenylated cysteinyl amide inhibitors. Oncotarget 9:40, pages 25781-25795.
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Jingsheng Yuan, Zhijie Yin, Kaixiong Tao, Guobing Wang & Jinbo Gao. (2017) Function of insulin‑like growth factor 1 receptor in cancer resistance to chemotherapy (Review). Oncology Letters.
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G. E. Morozevich, N. I. Kozlova, O. Y. Susova, A. Y. Lupatov & A. E. Berman. (2017) Hyperexpression of integrin α5β1 promotes resistance of MCF-7 human breast carcinoma cells to doxorubicin via ERK protein kinase down-regulation. Biochemistry (Moscow) 82:9, pages 1017-1024.
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Masanobu Tsubaki, Makiko Komai, Tatsuki Itoh, Motohiro Imano, Kotaro Sakamoto, Hirotaka Shimaoka, Tomoya Takeda, Naoki Ogawa, Kenji Mashimo, Daiichiro Fujiwara, Junji Mukai, Katsuhiko Sakaguchi, Takao Satou & Shozo Nishida. (2014) By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells. Leukemia Research 38:1, pages 121-130.
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Min Jiang, Ou Huang, Zuoquan Xie, Shuchao Wu, Xi Zhang, Aijun Shen, Hongchun Liu, Xiaosong Chen, Jiayi Wu, Ying Lou, Yan Mao, Kan Sun, Shudong Hu, Meiyu Geng & Kunwei Shen. (2014) A novel long non-coding RNA-ARA: Adriamycin Resistance Associated. Biochemical Pharmacology 87:2, pages 254-283.
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Qing-Zhi Long, Ming Zhou, Xiao-Gang Liu, Yue-Feng Du, Jin-Hai Fan, Xiang Li & Da-Lin He. (2013) Interaction of CCN1 with αvβ3 integrin induces P-glycoprotein and confers vinblastine resistance in renal cell carcinoma cells. Anti-Cancer Drugs 24:8, pages 810-817.
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Karina J. Price, Anna Tsykin, Keith M. Giles, Rosemary T. Sladic, Michael R. Epis, Ruth Ganss, Gregory J. Goodall & Peter J. Leedman. (2012) Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines. Biochemical and Biophysical Research Communications 427:2, pages 343-348.
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G. E. Morozevich, N. I. Kozlova, N. A. Ushakova, M. E. Preobrazhenskaya & A. E. Berman. (2011) Involvement of integrin α5β1 in apoptosis and drug resistance of human breast carcinoma cells. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 5:3, pages 241-245.
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G.E. Morozevich, N.I. Kozlova, N.A. Ushakova, M.E. Preobrazhenskaya & A.E. Berman. (2011) Implication of integrin α5β1 in human breast carcinoma apoptosis and drug resistance. Biomeditsinskaya Khimiya 57:1, pages 77-84.
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K Tajima, R Ohashi, Y Sekido, T Hida, T Nara, M Hashimoto, S Iwakami, K Minakata, T Yae, F Takahashi, H Saya & K Takahashi. (2010) Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells. Oncogene 29:13, pages 1941-1951.
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Aili Gao, Xiangjing Wang, Wensheng Xiang, Hongsheng Liang, Jiguo Gao & Yijun Yan. (2010) Reversal of P-glycoprotein-mediated multidrug resistance in vitro by doramectin and nemadectin . Journal of Pharmacy and Pharmacology 62:3, pages 393-399.
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Ramakumar Tummala, Daniel Wolle, Sonali P. Barwe, Valerie B. Sampson, Ayyappan K. Rajasekaran & Lakshmi Pendyala. (2009) Expression of Na,K-ATPase-β1 subunit increases uptake and sensitizes carcinoma cells to oxaliplatin. Cancer Chemotherapy and Pharmacology 64:6, pages 1187-1194.
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A. A. Terentiev & N. T. Moldogazieva. (2007) Cell adhesion proteins and α-fetoprotein. Similar structural motifs as prerequisites for common functions. Biochemistry (Moscow) 72:9, pages 920-935.
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G. E. Morozevich, N. I. Kozlova, M. E. Preobrazhenskaya, N. A. Ushakova, I. A. Eltsov, A. A. Shtil & A. E. Berman. (2006) The role of β1 integrin subfamily in anchorage-dependent apoptosis of breast carcinoma cells differing in multidrug resistance. Biochemistry (Moscow) 71:5, pages 489-495.
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Monica Biscardi, Elisabetta Teodori, Roberto Caporale, Roberta Budriesi, Francesca Balestri, Barbara Scappini, Sabrina Gavazzi & Alberto Grossi. (2006) Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity. Leukemia Research 30:1, pages 1-8.
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Katherine L. Schaefer, Koichiro Wada, Hirokazu Takahashi, Nobuyuki Matsuhashi, Shin Ohnishi, M. Michael Wolfe, Jerrold R. Turner, Atsushi Nakajima, Steven C. Borkan & Lawrence J. Saubermann. (2005) Peroxisome Proliferator-Activated Receptor γ Inhibition Prevents Adhesion to the Extracellular Matrix and Induces Anoikis in Hepatocellular Carcinoma Cells. Cancer Research 65:6, pages 2251-2259.
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Dian L. Olson, Linda C. Burkly, Diane R. Leone, Brian M. Dolinski & Roy R. Lobb. (2005) Anti-α4 integrin monoclonal antibody inhibits multiple myeloma growth in a murine model. Molecular Cancer Therapeutics 4:1, pages 91-99.
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