Citations (76)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Yun-Feng Hu, Xia Lei, Hong-Yi Zhang, Jun-wei Ma, Wei-wei Yang, Min-lin Chen, Jie Cui & Hong Zhao. (2015) Expressions and clinical significance of autophagy-related markers Beclin1, LC3, and EGFR in human cervical squamous cell carcinoma. OncoTargets and Therapy 8, pages 2243-2249.
Read now
Read now
A.K. Gupta, S.S. Bhunia, V.M. Balaramnavar & A.K. Saxena. (2011) Pharmacophore modelling, molecular docking and virtual screening for EGFR (HER 1) tyrosine kinase inhibitors. SAR and QSAR in Environmental Research 22:3-4, pages 239-263.
Read now
Read now
Susanne J Rogers, Kevin J Harrington, Suzanne A Eccles & Christopher M Nutting. (2004) Combination epidermal growth factor receptor inhibition and radical radiotherapy for NSCLC. Expert Review of Anticancer Therapy 4:4, pages 569-583.
Read now
Read now
Articles from other publishers (73)
Xiuli Zheng, Xiaohai Song, Guonian Zhu, Dayi Pan, Haonan Li, Jiankun Hu, Kai Xiao, Qiyong Gong, Zhongwei Gu, Kui Luo & Weimin Li. (2023) Nanomedicine Combats Drug Resistance in Lung Cancer. Advanced Materials.
Crossref
Crossref
JiHoon Kang, Jaemoo Chun, Jung Seok Hwang, Chaoyun Pan, Jie Li, Austin C. Boese, Isabelle Young, Courteney M. Malin, Yibin Kang, Don L. Gibbons, Gabriel Sica, Haian Fu, Suresh S. Ramalingam, Lingtao Jin & Sumin Kang. (2022) EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer. Cell Reports 41:11, pages 111827.
Crossref
Crossref
Siyao Liu, Kaycee Nguyen, Dongyong Park, Nelson Wong, Anson Wang & Yubin Zhou. (2022) Harnessing natural killer cells to develop next‐generation cellular immunotherapy. Chronic Diseases and Translational Medicine 8:4, pages 245-255.
Crossref
Crossref
Altan Kara, Aykut Özgür, Şaban Tekin & Yusuf Tutar. (2022) Computational Analysis of Drug Resistance Network in Lung Adenocarcinoma. Anti-Cancer Agents in Medicinal Chemistry 22:3, pages 566-578.
Crossref
Crossref
Poorigali Raghavendra-Rao Sowmya, Rudrappa Ambedkar & Rangaswamy Lakshminarayana. 2022. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
1407
1426
.
Ranjan Pathak & Victoria M. Villaflor. (2021) Histologic Transformation in EGFR-Mutant Lung Adenocarcinomas: Mechanisms and Therapeutic Implications. Cancers 13:18, pages 4641.
Crossref
Crossref
Antonio Passaro, Pasi A. Jänne, Tony Mok & Solange Peters. (2021) Overcoming therapy resistance in EGFR-mutant lung cancer. Nature Cancer 2:4, pages 377-391.
Crossref
Crossref
Poorigali Raghavendra-Rao Sowmya, Rudrappa Ambedkar & Rangaswamy Lakshminarayana. 2020. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
1
20
.
Mei Mei, Yu-Huan Chen, Tian Meng, Ling-Han Qu, Zhi-Yong Zhang & Xiao Zhang. (2020)
Comparative efficacy and safety of radiotherapy/cetuximab
versus
radiotherapy/chemotherapy for locally advanced head and neck squamous cell carcinoma patients: a systematic review of published, primarily non-randomized, data
. Therapeutic Advances in Medical Oncology 12, pages 175883592097535.
Crossref
Crossref
Chichirau, Diechler, Posselt & Wessler. (2019) Tyrosine Kinases in Helicobacter pylori Infections and Gastric Cancer. Toxins 11:10, pages 591.
Crossref
Crossref
Qiang Zhou, Jiangbo Ren, Jinxuan Hou, Gang Wang, Lingao Ju, Yu Xiao & Yan Gong. (2019) Co-expression network analysis identified candidate biomarkers in association with progression and prognosis of breast cancer. Journal of Cancer Research and Clinical Oncology 145:9, pages 2383-2396.
Crossref
Crossref
Ji Su Lee, Yeong A. Kim, Young Jin Jang, Yongtaek Oh & Sanguine Byun. (2019) Dihydrocapsaicin Inhibits Epithelial Cell Transformation through Targeting Amino Acid Signaling and c-Fos Expression. Nutrients 11:6, pages 1269.
Crossref
Crossref
Stamatios Theocharis, Constantinos Giaginis, Eugene Dana, Irene Thymara, Jose Rodriguez, Efstratios Patsouris & Jerzy Klijanienko. (2017) Phosphorylated Epidermal Growth Factor Receptor Expression Is Associated With Clinicopathologic Parameters and Patient Survival in Mobile Tongue Squamous Cell Carcinoma. Journal of Oral and Maxillofacial Surgery 75:3, pages 632-640.
Crossref
Crossref
S.W. Aziz & M.H. Aziz. 2017. Introduction to Cancer Metastasis. Introduction to Cancer Metastasis
77
94
.
Luis Monteiro & Saman Warnakulasuriya. 2017. Squamous cell Carcinoma. Squamous cell Carcinoma
97
111
.
Zhuo Chen, Suresh Ramalingam & Dong M. Shin. 2017. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer
709
726
.
Dong Ju Son, Ji Eun Hong, Jung Ok Ban, Ju Ho Park, Hye Lim Lee, Sun Mi Gu, Jae Yeon Hwang, Myung Hee Jung, Dong Won Lee, Sang-Bae Han & Jin Tae Hong. (2015)
Synergistic Inhibitory Effects of Cetuximab and Cisplatin on Human Colon Cancer Cell Growth
via
Inhibition of the ERK-Dependent EGF Receptor Signaling Pathway
. BioMed Research International 2015, pages 1-13.
Crossref
Crossref
Jie Cui, Yun-Feng Hu, Xie-Min Feng, Tao Tian, Ya-Huan Guo, Jun-Wei Ma, Ke-Jun Nan & Hong-Yi Zhang. (2014) EGFR inhibitors and autophagy in cancer treatment. Tumor Biology 35:12, pages 11701-11709.
Crossref
Crossref
Xuehui Hou, Jingyu Zhang, Xuan Zhao, Liming Chang, Ping Hu & Hongmin Liu. (2014) Design, Synthesis and Bioactivities Evaluation of Novel Quinazoline Analogs Containing Oxazole Units. Chinese Journal of Chemistry 32:6, pages 538-544.
Crossref
Crossref
LS Monteiro, S Ricardo, ML Delgado, F Garcez, B do Amaral & C Lopes. (2014) Phosphorylated EGFR at tyrosine 1173 correlates with poor prognosis in oral squamous cell carcinomas. Oral Diseases 20:2, pages 178-185.
Crossref
Crossref
Christina L. Addison. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer
1559
1565
.
Christina L. Addison. 2014. Encyclopedia of Cancer. Encyclopedia of Cancer
1
7
.
Heddy Zola, Daniel Thomas & Angel Lopez. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Yongjun Mao, Wenxiu Zhu, Xiaoguang Kong, Zhen Wang, Hua Xie, Jian Ding, Nicholas Kenneth Terrett, Jingkang Shen & Jingshan Shen. (2013) Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry 21:11, pages 3090-3104.
Crossref
Crossref
Anette Weyergang, Pål K. Selbo & Kristian Berg. (2013) Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy. Biochimica et Biophysica Acta (BBA) - General Subjects 1830:3, pages 2659-2670.
Crossref
Crossref
Baowei Su, Arzu Cengizeroglu, Katarina Farkasova, Joana R. Viola, Martina Anton, Joachim W. Ellwart, Rudolf Haase, Ernst Wagner & Manfred Ogris. (2013) Systemic TNFα Gene Therapy Synergizes With Liposomal Doxorubicine in the Treatment of Metastatic Cancer. Molecular Therapy 21:2, pages 300-308.
Crossref
Crossref
Jeffrey S. Ross. 2013. Genomic and Personalized Medicine. Genomic and Personalized Medicine
798
819
.
EUN-SUN CHOI, SUNG-DAE CHO, JI-AE SHIN, KI HAN KWON, NAM-PYO CHO & JUNG-HYUN SHIM. (2012) Althaea rosea Cavanil and Plantago major L. suppress neoplastic cell transformation through the inhibition of epidermal growth factor receptor kinase. Molecular Medicine Reports 6:4, pages 843-847.
Crossref
Crossref
Yongjun Mao, Kai Xie, Wenxiu Zhu, Jianfeng Li, Hua Xie, Jian Ding, Nicholas Kenneth Terrett, Jingkang Shen & Jingshan Shen. (2012) WITHDRAWN: Design, synthesis and biological evaluation of 3-substituted-4-anilinequinoline as EGFR tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters.
Crossref
Crossref
Luís Silva Monteiro, Márcio Diniz‐Freitas, Tomás Garcia‐Caballero, Saman Warnakulasuriya, Jerónimo Forteza & Máximo Fraga. (2012) Combined cytoplasmic and membranous EGFR and p53 overexpression is a poor prognostic marker in early stage oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 41:7, pages 559-567.
Crossref
Crossref
A. SchäferA. PahnkeD. SchaffertW.M. van WeerdenC.M.A. de RidderW. RödlA. VetterC. SpitzwegR. KraaijE. WagnerM. Ogris. (2011) Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation. Human Gene Therapy 22:12, pages 1463-1473.
Crossref
Crossref
Shuping Xu & Zhang Weihua. (2011) Loss of EGFR induced autophagy sensitizes hormone refractory prostate cancer cells to adriamycin. The Prostate 71:11, pages 1216-1224.
Crossref
Crossref
Jennifer L. Hunt. (2011) An Update on Molecular Diagnostics of Squamous and Salivary Gland Tumors of the Head and Neck. Archives of Pathology & Laboratory Medicine 135:5, pages 602-609.
Crossref
Crossref
Jennifer L. Hunt. 2011. Diagnostic Immunohistochemistry. Diagnostic Immunohistochemistry
256
290
.
Dong Eun Lee, Ki Won Lee, Nu Ry Song, Sang Kwon Seo, Yong-Seok Heo, Nam Joo Kang, Ann M. Bode, Hyong Joo Lee & Zigang Dong. (2010) 7,3′,4′-Trihydroxyisoflavone Inhibits Epidermal Growth Factor-induced Proliferation and Transformation of JB6 P+ Mouse Epidermal Cells by Suppressing Cyclin-dependent Kinases and Phosphatidylinositol 3-Kinase. Journal of Biological Chemistry 285:28, pages 21458-21466.
Crossref
Crossref
Kenneth E. Rosenzweig, Chein Peter Chen, Sue S. Yom & Lee M. Krug. 2010. Leibel and Phillips Textbook of Radiation Oncology. Leibel and Phillips Textbook of Radiation Oncology
737
771
.
Jeffrey S. Ross. 2010. Essentials of Genomic and Personalized Medicine. Essentials of Genomic and Personalized Medicine
532
547
.
Manuel Rieber & Mary Strasberg Rieber. (2009) DN-R175H p53 mutation is more effective than p53 interference in inducing epithelial disorganization and activation of proliferation signals in human carcinoma cells: Role of E-cadherin. International Journal of Cancer 125:7, pages 1604-1612.
Crossref
Crossref
L. S. Monteiro, M. J. Bento, C. Palmeira & C. Lopes. (2009) Epidermal growth factor receptor immunoexpression evaluation in malignant salivary gland tumours. Journal of Oral Pathology & Medicine 38:6, pages 508-513.
Crossref
Crossref
Alex G. Waterson, Kimberly G. Petrov, Keith R. Hornberger, Robert D. Hubbard, Douglas M. Sammond, Stephon C. Smith, Hamilton D. Dickson, Thomas R. Caferro, Kevin W. Hinkle, Kirk L. Stevens, Scott H. Dickerson, David W. Rusnak, Glenn M. Spehar, Edgar R. Wood, Robert J. Griffin & David E. Uehling. (2009) Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 19:5, pages 1332-1336.
Crossref
Crossref
Kirk L. Stevens, Krystal J. Alligood, Jennifer G. Badiang Alberti, Thomas R. Caferro, Stanley D. Chamberlain, Scott H. Dickerson, Hamilton D. Dickson, Holly K. Emerson, Robert J. Griffin, Robert D. Hubbard, Barry R. Keith, Robert J. Mullin, Kimberly G. Petrov, Roseanne M. Gerding, Michael J. Reno, Tara R. Rheault, David W. Rusnak, Douglas M. Sammond, Stephon C. Smith, David E. Uehling, Alex G. Waterson & Edgar R. Wood. (2009) Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors. Bioorganic & Medicinal Chemistry Letters 19:1, pages 21-26.
Crossref
Crossref
Jeffrey S. Ross. 2009. Genomic and Personalized Medicine. Genomic and Personalized Medicine
990
1007
.
Paola Palozza, Simona Serini, Maria Ameruso & Sara Verdecchia. 2009. Carotenoids. Carotenoids
211
234
.
Christian Dohmen & Manfred Ogris. 2009. Pharmaceutical Perspectives of Cancer Therapeutics. Pharmaceutical Perspectives of Cancer Therapeutics
269
295
.
Robert D. Hubbard, Scott H. Dickerson, Holly K. Emerson, Robert J. Griffin, Michael J. Reno, Keith R. Hornberger, David W. Rusnak, Edgar R. Wood, David E. Uehling & Alex G. Waterson. (2008) Dual EGFR/ErbB-2 inhibitors from novel pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines. Bioorganic & Medicinal Chemistry Letters 18:21, pages 5738-5740.
Crossref
Crossref
Jeffrey S. Ross. 2008. Pharmacogenomics and Personalized Medicine. Pharmacogenomics and Personalized Medicine
267
298
.
Timothy Craig Allen, Anna Sienko & Philip T. Cagle. 2008. Molecular Pathology of Lung Diseases. Molecular Pathology of Lung Diseases
226
232
.
Philip T. Cagle, Jaishree Jagirdar & Helmut H. Popper. 2008. Dail and Hammar’s Pulmonary Pathology. Dail and Hammar’s Pulmonary Pathology
47
157
.
Levy Kopelovich, Judith R. Fay, Caroline C. Sigman & James A. Crowell. (2007) The Mammalian Target of Rapamycin Pathway as a Potential Target for Cancer Chemoprevention. Cancer Epidemiology, Biomarkers & Prevention 16:7, pages 1330-1340.
Crossref
Crossref
Omar M. Fattah, Sylvain M. Cloutier, Christoph Kündig, Loyse M. Felber, Christian M. Gygi, Patrice Jichlinski, Hans-Jürg Leisinger, Eric R. Gauthier, Jean Pierre Mach & David Deperthes. (2006) Peptabody-EGF: A novel apoptosis inducer targeting ErbB1 receptor overexpressing cancer cells. International Journal of Cancer 119:10, pages 2455-2463.
Crossref
Crossref
Klaus Brischwein, Bernd Schlereth, Benjamin Guller, Carola Steiger, Andreas Wolf, Ralf Lutterbuese, Sonja Offner, Mathias Locher, Thomas Urbig, Tobias Raum, Petra Kleindienst, Pauline Wimberger, Rainer Kimmig, Iduna Fichtner, Peter Kufer, Robert Hofmeister, Antonio J. da Silva & Patrick A. Baeuerle. (2006) MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Molecular Immunology 43:8, pages 1129-1143.
Crossref
Crossref
JOHN K. BUOLAMWINI. 2006. Novel Anticancer Agents. Novel Anticancer Agents
1
35
.
Jennifer L. Hunt & Leon Barnes. 2006. Diagnostic Immunohistochemistry. Diagnostic Immunohistochemistry
227
260
.
Melanie B. Thomas & James L. Abbruzzese. (2005) Opportunities for Targeted Therapies in Hepatocellular Carcinoma. Journal of Clinical Oncology 23:31, pages 8093-8108.
Crossref
Crossref
Matthew A. J. Duncton, Leon M. Smith, Sabina Burdzovic-Wizeman, Aaron Burns, Hu Liu, Yunyu Mao, Wai C. Wong & Alexander S. Kiselyov. (2005)
Preparation of Substituted Pyrimido[4,5-
b
]-1,4-benzoxazepines, Thiazepines, and Diazepines via a Pictet−Spengler Cyclization
. The Journal of Organic Chemistry 70:23, pages 9629-9631.
Crossref
Crossref
Janine Smith. (2005) Erlotinib: Small-molecule targeted therapy in the treatmentof non-small-cell lung cancer. Clinical Therapeutics 27:10, pages 1513-1534.
Crossref
Crossref
Raoul TibesJonathan TrentRazelle Kurzrock. (2005) TYROSINE KINASE INHIBITORS AND THE DAWN OF MOLECULAR CANCER THERAPEUTICS. Annual Review of Pharmacology and Toxicology 45:1, pages 357-384.
Crossref
Crossref
Mi Sun Choe, Xin Zhang, Hyung Ju C. Shin, Dong M. Shin & Zhuo (Georgia) Chen. (2005) Interaction between epidermal growth factor receptor– and cyclooxygenase 2–mediated pathways and its implications for the chemoprevention of head and neck cancer. Molecular Cancer Therapeutics 4:9, pages 1448-1455.
Crossref
Crossref
Jian-Xin Lu, Ying Peng, Zhe-Feng Meng, Li-Qin Jin, Yong-Sui Lu & Min-Xin Guan. (2005) Rational design of an EGF-IL18 fusion protein: Implication for developing tumor therapeutics. Biochemical and Biophysical Research Communications 334:1, pages 157-161.
Crossref
Crossref
M Everts, S-A Kim-Park, M A Preuss, M J Passineau, J N Glasgow, A V Pereboev, P J Mahasreshti, W E Grizzle, P N Reynolds & D T Curiel. (2005) Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors. Gene Therapy 12:13, pages 1042-1048.
Crossref
Crossref
Dan Lu, Haifan Zhang, Henry Koo, James Tonra, Paul Balderes, Marie Prewett, Eric Corcoran, Venkata Mangalampalli, Rajiv Bassi, Deborah Anselma, Dipa Patel, Xiaoqiang Kang, Dale L. Ludwig, Daniel J. Hicklin, Peter Bohlen, Larry Witte & Zhenping Zhu. (2005) A Fully Human Recombinant IgG-like Bispecific Antibody to Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor for Enhanced Antitumor Activity. Journal of Biological Chemistry 280:20, pages 19665-19672.
Crossref
Crossref
Peilin Zhang & John Rogers. (2005) Targeted lung cancer therapy: what have we learned from gefitinib?. Therapy 2:1, pages 1-2.
Crossref
Crossref
M. Kullberg, K. Mann & J.L. Owens. (2005) Improved drug delivery to cancer cells: a method using magnetoliposomes that target epidermal growth factor receptors. Medical Hypotheses 64:3, pages 468-470.
Crossref
Crossref
Richard M. Schultz. 2005. Advances in Targeted Cancer Therapy. Advances in Targeted Cancer Therapy
1
17
.
Rebecca G. Pomerantz & Jennifer Rubin Grandis. (2004) The epidermal growth factor receptor signaling network in head and neck carcinogenesis and implications for targeted therapy. Seminars in Oncology 31:6, pages 734-743.
Crossref
Crossref
Paola Palozza, Simona Serini, Fiorella Di Nicuolo & Gabriella Calviello. (2004) Modulation of apoptotic signalling by carotenoids in cancer cells. Archives of Biochemistry and Biophysics 430:1, pages 104-109.
Crossref
Crossref
Ray Hinerman, Weiyi Gao, Hassan H Ramadan, Cynthia Cunningham & Peilin Zhang. (2004)
Erlotinib (Tarceva
®
) inhibits oral cavity carcinoma and synergizes with cisplatin and ionizing radiation in vitro
. Therapy 1:1, pages 67-74.
Crossref
Crossref
Ray Hinerman, Weiyi Gao, Hassan H Ramadan, Cynthia Cunningham & Peilin Zhang. (2004) Erlotinib (TarcevaR) inhibits oral cavity carcinoma and synergizes with cisplatin and ionizing radiation in vitro. Therapy 1:1, pages 67-74.
Crossref
Crossref
A. McKechnie, R.A. Robins & O. Eremin. (2004) Immunological aspects of head and neck cancer: Biology, pathophysiology and therapeutic mechanisms. The Surgeon 2:4, pages 187-207.
Crossref
Crossref
John W. Park, Robert S. Kerbel, Gary J. Kelloff, J. Carl Barrett, Bruce A. Chabner, David R. Parkinson, Jonathan Peck, Raymond W. Ruddon, Caroline C. Sigman & Dennis J. Slamon. (2004) Rationale for Biomarkers and Surrogate End Points in Mechanism-Driven Oncology Drug Development. Clinical Cancer Research 10:11, pages 3885-3896.
Crossref
Crossref
Peter M Smith-Jones, David B Solit, Timothy Akhurst, Farzana Afroze, Neal Rosen & Steven M Larson. (2004) Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors. Nature Biotechnology 22:6, pages 701-706.
Crossref
Crossref
Jeffrey S. Ross, David P. Schenkein, Robert Pietrusko, Mark Rolfe, Gerald P. Linette, James Stec, Nancy E. Stagliano, Geoffrey S. Ginsburg, W. Fraser Symmans, Lajos Pusztai & Gabriel N. Hortobagyi. (2004) Targeted Therapies for Cancer 2004. American Journal of Clinical Pathology 122:4, pages 598-609.
Crossref
Crossref
Dan Lu, Haifan Zhang, Dale Ludwig, Anita Persaud, Xenia Jimenez, Douglas Burtrum, Paul Balderes, Meilin Liu, Peter Bohlen, Larry Witte & Zhenping Zhu. (2004) Simultaneous Blockade of Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor Signaling Pathways in Cancer Cells with a Fully Human Recombinant Bispecific Antibody. Journal of Biological Chemistry 279:4, pages 2856-2865.
Crossref
Crossref