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Drug Profile

Synthetic retinoid fenretinide in breast cancer chemoprevention

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Pages 423-432 | Published online: 10 Jan 2014

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Danielle G Smith, Tapiwanashe Magwere & Susan A Burchill. (2011) Oxidative stress and therapeutic opportunities: focus on the Ewing’s sarcoma family of tumors. Expert Review of Anticancer Therapy 11:2, pages 229-249.
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Cecilia Oluwamodupe & Adesola Oluwaseun Adeleye. (2023) Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases. Cardiovascular Toxicology.
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Noheul Kim & Ronny Priefer. (2021) Retinol binding protein 4 antagonists and protein synthesis inhibitors: Potential for therapeutic development. European Journal of Medicinal Chemistry 226, pages 113856.
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Di Zhang, Bijay Singh, Jessica Moerland, Owen Mitchell, Lizbeth Lockwood, Sarah Carapellucci, Srinivas Sridhar & Karen T. Liby. (2021) Sustained, local delivery of the PARP inhibitor talazoparib prevents the development of mammary gland hyperplasia in Brca1-deficient mice. Scientific Reports 11:1.
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Rurina Watanuki, Aiko Nagayama, Tetsu Hayashida & Yuko Kitagawa. 2021. Hereditary Breast and Ovarian Cancer. Hereditary Breast and Ovarian Cancer 129 148 .
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Nithin B. Boppana, Jeremy S. DeLor, Eric Van Buren, Alicja Bielawska, Jacek Bielawski, Jason S. Pierce, Mladen Korbelik & Duska Separovic. (2016) Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway. Journal of Photochemistry and Photobiology B: Biology 159, pages 191-195.
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Jeong-Won Lee, Ji-Yoon Ryu, Gun Yoon, Hye-Kyung Jeon, Young-Jae Cho, Jung-Joo Choi, Sang Yong Song, In-Gu Do, Yoo-Young Lee, Tae-Joong Kim, Chel Hun Choi, Byoung-Gie Kim & Duk-Soo Bae. (2015) Sphingosine kinase 1 as a potential therapeutic target in epithelial ovarian cancer. International Journal of Cancer 137:1, pages 221-229.
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N. Ditsch & M. Kiechle. (2014) BRCA-Mutation und medikamentöse PräventionBRCA mutations and preventive drug therapy. Der Gynäkologe 47:10, pages 753-758.
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Melissa E Smith, Bhaskar C Das & Ganjam V Kalpana. (2011) In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines. Cancer Cell International 11:1.
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Matteo Lazzeroni, Sara Gandini, Matteo Puntoni, Bernardo Bonanni, Alessandra Gennari & Andrea DeCensi. (2011) The science behind vitamins and natural compounds for breast cancer prevention. Getting the most prevention out of it. The Breast 20, pages S36-S41.
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Mehrdad Rahmaniyan, Robert W. CurleyJrJr, Lina M. Obeid, Yusuf A. Hannun & Jacqueline M. Kraveka. (2011) Identification of Dihydroceramide Desaturase as a Direct in Vitro Target for Fenretinide. Journal of Biological Chemistry 286:28, pages 24754-24764.
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Donald J. AbrahamMarcia I. Dawson. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 369 546 .
Manuela Valsecchi, Massimo Aureli, Laura Mauri, Giuditta Illuzzi, Vanna Chigorno, Alessandro Prinetti & Sandro Sonnino. (2010) Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids. Journal of Lipid Research 51:7, pages 1832-1840.
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Giuditta Illuzzi, Caterina Bernacchioni, Massimo Aureli, Simona Prioni, Gianluca Frera, Chiara Donati, Manuela Valsecchi, Vanna Chigorno, Paola Bruni, Sandro Sonnino & Alessandro Prinetti. (2010) Sphingosine Kinase Mediates Resistance to the Synthetic Retinoid N-(4-Hydroxyphenyl)retinamide in Human Ovarian Cancer Cells. Journal of Biological Chemistry 285:24, pages 18594-18602.
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Patricia F. Coogan. 2010. Breast Cancer Epidemiology. Breast Cancer Epidemiology 243 260 .
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Bhaskar C. Das, Melissa E. Smith & Ganjam V. Kalpana. (2008) Design and synthesis of 4-HPR derivatives for rhabdoid tumors. Bioorganic & Medicinal Chemistry Letters 18:13, pages 3805-3808.
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K.H. Baumann & U. Wagner. (2008) Präventionsstrategien beim OvarialkarzinomPrevention strategies for ovarian cancer. Der Gynäkologe 41:7, pages 513-522.
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