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Current concepts on the surgical and medical management of osteosarcoma

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Pages 1257-1269 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Yiping Zhang, Changchang Yin, Xufeng Zhou, Yahua Wu & Lili Wang. (2019) Silencing of estrogen receptor β promotes the invasion and migration of osteosarcoma cells through activating Wnt signaling pathway. OncoTargets and Therapy 12, pages 6779-6788.
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Miaozhong Ni, Min Xiong, Xinchao Zhang, Guoping Cai, Huaiwen Chen, Qingmin Zeng & Zuochong Yu. (2015) Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133+ osteosarcoma cancer stem cells. International Journal of Nanomedicine 10, pages 2537-2554.
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Articles from other publishers (54)

Shunguang Chen, Yan Xu & Bo Yang. (2023) CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma. Functional & Integrative Genomics 23:3.
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Juan Tornín, Miguel Mateu-Sanz, Verónica Rey, Dzohara Murillo, Carmen Huergo, Borja Gallego, Aida Rodríguez, René Rodríguez & Cristina Canal. (2023) Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma. Redox Biology 62, pages 102685.
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Yiming Zhang, Wenyi Gan, Nan Ru, Zhaowen Xue, Wenjie Chen, Zihang Chen, Huajun Wang & Xiaofei Zheng. (2023) Comprehensive multi-omics analysis reveals m7G-related signature for evaluating prognosis and immunotherapy efficacy in osteosarcoma. Journal of Bone Oncology 40, pages 100481.
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Ginevra Passeri, Ruby A. Vincent, Zhiyin Xiao, Joshua Northcote‐Smith & Kogularamanan Suntharalingam. (2023) Encapsulation and Delivery of an Osteosarcoma Stem Cell Active Gallium(III)‐Diflunisal Complex Using Polymeric Micelles. ChemMedChem 18:4.
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Ruby A. Vincent, Ginevra Passeri, Joshua Northcote‐Smith, Kuldip Singh & Kogularamanan Suntharalingam. (2022) The Osteosarcoma Stem Cell Activity of a Gallium(III)‐Phenanthroline Complex Appended to Salicylate. ChemBioChem 23:24.
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Yang Wang, Liang Zhang, Guosheng Zhao, Yuan Zhang, Fangbiao Zhan, Zhiyu Chen, Tao He, Yang Cao, Lan Hao, Zhigang Wang, Zhengxue Quan & Yunsheng Ou. (2022) Homologous targeting nanoparticles for enhanced PDT against osteosarcoma HOS cells and the related molecular mechanisms. Journal of Nanobiotechnology 20:1.
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Tao He, Xiaohong Lin, Chaohua Yang, Zhiyu Chen, Linbang Wang, Qiaochu Li, Jingjin Ma, Fangbiao Zhan, Yang Wang, Jin Yan & Zhengxue Quan. (2022) Theaflavin-3,3 -Digallate Plays a ROS-Mediated Dual Role in Ferroptosis and Apoptosis via the MAPK Pathway in Human Osteosarcoma Cell Lines and Xenografts . Oxidative Medicine and Cellular Longevity 2022, pages 1-20.
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Lijun Peng, Huapan Fang, Xiao Yang & Xi Zeng. (2022) Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma. Frontiers in Chemistry 10.
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Chen Sun, Chi Chen, Zhen Chen, Jun Guo, Zhi-Hong Yu, Wei Qian, Fen Ai, Liang Xiao & Xiao Guo. (2022) MicroRNA-181a-5p Promotes Osteosarcoma Progression via PTEN/AKT Pathway. Analytical Cellular Pathology 2022, pages 1-13.
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Mohammad Tobeiha, Ali Rajabi, Arash Raisi, Mahshad Mohajeri, Soheil Mohammadi Yazdi, Amirhossein Davoodvandi, Fatemeh Aslanbeigi, MohamadSadegh Vaziri, Michael R. Hamblin & Hamed Mirzaei. (2021) Potential of natural products in osteosarcoma treatment: Focus on molecular mechanisms. Biomedicine & Pharmacotherapy 144, pages 112257.
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Zhiyin Xiao, Ginevra Passeri, Joshua Northcote‐Smith, Kuldip Singh & Kogularamanan Suntharalingam. (2021) Osteosarcoma Stem Cell Potent Gallium(III)‐Polypyridyl Complexes Bearing Diflunisal. Chemistry – A European Journal 27:55, pages 13846-13854.
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Isabel Fernandes, Cecília Melo-Alvim, Raquel Lopes-Brás, Miguel Esperança-Martins & Luís Costa. (2021) Osteosarcoma Pathogenesis Leads the Way to New Target Treatments. International Journal of Molecular Sciences 22:2, pages 813.
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Jing-Yi Sun, Ya-Jun Hou, Hai-Juan Cui, Cheng Zhang, Ming-Feng Yang, Feng-Ze Wang, Zheng Sun, Cun-Dong Fan, Bao-Liang Sun & Jin Rok Oh. (2020) VS-5584 Inhibits Human Osteosarcoma Cells Growth by Induction of G1- phase Arrest through Regulating PI3K/mTOR and MAPK Pathways. Current Cancer Drug Targets 20:8, pages 616-623.
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Yu Zhang, Fengzan Li, Lei Qiu, Lihui Xu, Xiaohui Niu, Yao Sui, Shunli Zhang, Qing Zhang & Li Zhang. (2020) Toward Precise Osteotomies: A Coarse-to-Fine 3D Cut Plane Planning Method for Image-Guided Pelvis Tumor Resection Surgery. IEEE Transactions on Medical Imaging 39:5, pages 1511-1523.
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Perrine Robin, Kuldip Singh & Kogularamanan Suntharalingam. (2020) Gallium( iii )-polypyridyl complexes as anti-osteosarcoma stem cell agents . Chemical Communications 56:10, pages 1509-1512.
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Long Jiang, Shanshan Jiang, Wenjie Zhou, Jia Huang, Yongbin Lin, Hao Long & Qingquan Luo. (2019) Oxidized low density lipoprotein receptor 1 promotes lung metastases of osteosarcomas through regulating the epithelial-mesenchymal transition. Journal of Translational Medicine 17:1.
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Zonghui Guo, Yin Tang, Youwei Fu & Junjie Wang. (2019) Decreased expression of STAT5A predicts poor prognosis in osteosarcoma. Pathology - Research and Practice 215:3, pages 519-524.
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Keke Gui, Xinchao Zhang, Fangyi Chen, Zhe Ge, Shichao Zhang, Xiaoxia Qi, Jing Sun & Zuochong Yu. (2019) Lipid-polymer nanoparticles with CD133 aptamers for targeted delivery of all-trans retinoic acid to osteosarcoma initiating cells. Biomedicine & Pharmacotherapy 111, pages 751-764.
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Lihua Peng & Dianming Jiang. (2018) Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition. PLOS ONE 13:10, pages e0205918.
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Fangyi Chen, Yibin Zeng, Xiaoxia Qi, Yanchao Chen, Zhe Ge, Zengxin Jiang, Xinchao Zhang, Yinmei Dong, Huaiwen Chen & Zuochong Yu. (2018) Targeted salinomycin delivery with EGFR and CD133 aptamers based dual-ligand lipid-polymer nanoparticles to both osteosarcoma cells and cancer stem cells. Nanomedicine: Nanotechnology, Biology and Medicine 14:7, pages 2115-2127.
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Hao Qu, Yue Xue, Wenwen Lian, Cong Wang, Jia He, Qihong Fu, Lijia Zhong, Nong Lin, Lihua Lai, Zhaoming Ye & Qingqing Wang. (2018) Melatonin inhibits osteosarcoma stem cells by suppressing SOX9-mediated signaling. Life Sciences 207, pages 253-264.
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Jing Qiu, Yongzhi Zhang, Hu Chen & Zhi Guo. (2018) MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3. International Journal of Oncology.
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Zuochong Yu, Fangyi Chen, Xiaoxia Qi, Yinmei Dong, Yingying Zhang, Zhe Ge, Guoping Cai & Xinchao Zhang. (2017) Epidermal growth factor receptor aptamer‑conjugated polymer‑lipid hybrid nanoparticles enhance salinomycin delivery to osteosarcoma and cancer stem cells. Experimental and Therapeutic Medicine.
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Ying Yang & Sijie Fang. (2017) Small non-coding RNAs-based bone regulation and targeting therapeutic strategies. Molecular and Cellular Endocrinology 456, pages 16-35.
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Minfei Yang, Bing Liu, Libin Jin, Huimin Tao & Zhengming Yang. (2017) Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway. Journal of Bone Oncology 9, pages 15-20.
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Dong Cheng, Xubin Qiu, Ming Zhuang, Chenlei Zhu, Hongjun Zou & Zhiwei Liu. (2017) MicroRNAs with prognostic significance in osteosarcoma: a systemic review and meta-analysis. Oncotarget 8:46, pages 81062-81074.
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Yang Yang, Jing Chen & Qingzhong Chen. (2017) Upregulation of HOXB7 promotes proliferation and metastasis of osteosarcoma cells. Molecular Medicine Reports 16:3, pages 2773-2778.
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