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Emerging technologies in point-of-care molecular diagnostics for resource-limited settings

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Mekbib Astatke, Olivia Tiburzi & Amy Connolly. (2022) A novel RNA detection technique for point-of-care identification of pathogens. Journal of Immunoassay and Immunochemistry 43:2.
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Luc Bissonnette & Michel G. Bergeron. (2017) Portable devices and mobile instruments for infectious diseases point-of-care testing. Expert Review of Molecular Diagnostics 17:5, pages 471-494.
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Carolina Scagnolari, Ombretta Turriziani, Katia Monteleone, Alessandra Pierangeli & Guido Antonelli. (2017) Consolidation of molecular testing in clinical virology. Expert Review of Anti-infective Therapy 15:4, pages 387-400.
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Ameh James & Joanne Macdonald. (2015) Recombinase polymerase amplification: Emergence as a critical molecular technology for rapid, low-resource diagnostics. Expert Review of Molecular Diagnostics 15:11, pages 1475-1489.
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Sterghios Athanasios Moschos. (2015) Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis. Expert Review of Molecular Diagnostics 15:10, pages 1237-1240.
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Articles from other publishers (46)

Shivangi, Manish Kumar Mishra, Sachin Gupta, Konika Razdan, Shashi Sudan & Shelly Sehgal. (2023) Clinical diagnosis of Viral Hepatitis: current status and future strategies. Diagnostic Microbiology and Infectious Disease, pages 116151.
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Frederick R. Cross, Peter C. Fridy, Natalia E. Ketaren, Fred D. Mast, Song Li, J. Paul Olivier, Kresti Pecani, Brian T. Chait, John D. Aitchison & Michael P. Rout. (2023) Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2. Journal of Biological Chemistry 299:3, pages 102954.
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Ineka GowNicholas SmithDamien Stark & John Ellis. (2023) Molecular Detection of Neglected Tropical Diseases: The Case for Automated Near–Point-of-Care Diagnosis of Leishmaniasis. The American Journal of Tropical Medicine and Hygiene 108:1, pages 2-6.
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Jonathan E. Schmitz, Charles W. Stratton, David H. Persing & Yi-Wei Tang. (2022) Forty Years of Molecular Diagnostics for Infectious Diseases. Journal of Clinical Microbiology 60:10.
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. (2022) The potential of digital molecular diagnostics for infectious diseases in sub-Saharan Africa. PLOS Digital Health 1:6, pages e0000064.
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Fred D Mast, Peter C Fridy, Natalia E Ketaren, Junjie Wang, Erica Y Jacobs, Jean Paul Olivier, Tanmoy Sanyal, Kelly R Molloy, Fabian Schmidt, Magdalena Rutkowska, Yiska Weisblum, Lucille M Rich, Elizabeth R Vanderwall, Nicholas Dambrauskas, Vladimir Vigdorovich, Sarah Keegan, Jacob B Jiler, Milana E Stein, Paul Dominic B Olinares, Louis Herlands, Theodora Hatziioannou, D Noah Sather, Jason S Debley, David Fenyö, Andrej Sali, Paul D Bieniasz, John D Aitchison, Brian T Chait & Michael P Rout. (2021) Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape. eLife 10.
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Andreas Puyskens, Eva Krause, Janine Michel, C Micha Nübling, Heinrich Scheiblauer, Daniel Bourquain, Marica Grossegesse, Roman Valusenko, Victor M Corman, Christian Drosten, Katrin Zwirglmaier, Roman Wölfel, Constanze Lange, Jan Kramer, Johannes Friesen, Ralf Ignatius, Michael Müller, Jonas Schmidt-Chanasit, Petra Emmerich, Lars Schaade & Andreas Nitsche. (2021) Establishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021. Eurosurveillance 26:44.
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Emma C. Hobbs, Axel Colling, Ratna B. Gurung & John Allen. (2020) The potential of diagnostic point‐of‐care tests (POCTs) for infectious and zoonotic animal diseases in developing countries: Technical, regulatory and sociocultural considerations. Transboundary and Emerging Diseases 68:4, pages 1835-1849.
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Xiaolin Huang, Ruoyao Zhang, Chao Chen, Ryan T. K. Kwok & Ben Zhong Tang. (2021) Wash-free detection and bioimaging by AIEgens. Materials Chemistry Frontiers 5:2, pages 723-743.
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SR Nagalla, V Janaki, AR Vijayalakshmi, K Chayadevi, D Pratibha, PV Rao, KM Sage, D Nair‐Schaef, E Bean, CT RobertsJrJr & MG Gravett. (2020) Glycosylated fibronectin point‐of‐care test for diagnosis of pre‐eclampsia in a low‐resource setting: a prospective Southeast Asian population study. BJOG: An International Journal of Obstetrics & Gynaecology 127:13, pages 1687-1694.
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Kathy Jackson & Robert G. Gish. (2020) Point of Care Diagnostic Testing for Hepatitis B Virus. Current Hepatology Reports 19:3, pages 245-253.
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Manivanh VongsouvathTehmina BharuchaMalee SeephoneleeXavier de LamballeriePaul N. NewtonAudrey Dubot-Pérès. (2020) Harnessing Dengue Rapid Diagnostic Tests for the Combined Surveillance of Dengue, Zika, and Chikungunya Viruses in Laos. The American Journal of Tropical Medicine and Hygiene 102:6, pages 1244-1248.
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Anchal Malik. (2020) A good career start can open doors: the plusses and minuses of an international graduate student program—a student’s perspective. Medical Microbiology and Immunology 209:3, pages 225-227.
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Albert Lalremruata, The Trong Nguyen, Matthew B. B. McCall, Ghyslain Mombo-Ngoma, Selidji T. Agnandji, Ayôla A. Adegnika, Bertrand Lell, Michael Ramharter, Stephen L. Hoffman, Peter G. Kremsner & Benjamin Mordmüller. (2020) Recombinase Polymerase Amplification and Lateral Flow Assay for Ultrasensitive Detection of Low-Density Plasmodium falciparum Infection from Controlled Human Malaria Infection Studies and Naturally Acquired Infections. Journal of Clinical Microbiology 58:5.
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Desmond Kuupiel, Vitalis Bawontuo, Paul K. Drain, Nonjabulo Gwala & Tivani P. Mashamba-Thompson. (2019) Supply chain management and accessibility to point-of-care testing in resource-limited settings: a systematic scoping review. BMC Health Services Research 19:1.
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Kerry Atkinson & David MabeyA.C. Hurt & I.G. Barr. 2019. Revolutionizing Tropical Medicine. Revolutionizing Tropical Medicine 191 201 .
Yan Han, Yue-Ping Yin, Ming-Ying Zhong, Kai Chen, Mei-Qin Shi & Xiang-Sheng Chen. (2019) Suboptimal Chlamydia trachomatis Detection Method Is Still Widely Used in China: Results of External Quality Assessments from 2013 to 2018. International Journal of Dermatology and Venereology 2:3, pages 138-144.
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Kevin J. Land, Debrah I. Boeras, Xiang-Sheng Chen, Andrew R. Ramsay & Rosanna W. Peeling. (2018) REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes. Nature Microbiology 4:1, pages 46-54.
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Ana V. Ibarra-Meneses, Israel Cruz, Carmen Chicharro, Carmen Sánchez, Sylvain Biéler, Tobias Broger, Javier Moreno & Eugenia Carrillo. (2018) Evaluation of fluorimetry and direct visualization to interpret results of a loop-mediated isothermal amplification kit to detect Leishmania DNA. Parasites & Vectors 11:1.
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Omer Ceylan, Geetesh K. Mishra, Melik Yazici, Anjum Qureshi, Javed H. Niazi & Yasar Gurbuz. (2018) A Hand-Held Point-of-Care Biosensor Device for Detection of Multiple Cancer and Cardiac Disease Biomarkers Using Interdigitated Capacitive Arrays. IEEE Transactions on Biomedical Circuits and Systems 12:6, pages 1440-1449.
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Eda Celikbas, Emine Guler Celik & Suna Timur. (2018) Paper-Based Analytical Methods for Smartphone Sensing with Functional Nanoparticles: Bridges from Smart Surfaces to Global Health. Analytical Chemistry 90:21, pages 12325-12333.
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Michael Mauk, Jinzhao Song, Changchun Liu & Haim Bau. (2018) Simple Approaches to Minimally-Instrumented, Microfluidic-Based Point-of-Care Nucleic Acid Amplification Tests. Biosensors 8:1, pages 17.
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A. Jupe, P. Livshits, S. Kahnert, M. Figge, S. Mross, M. Goertz, H. Kappert, H. Vogt & A. Goehlich. 2018. Nanostructured Materials for the Detection of CBRN. Nanostructured Materials for the Detection of CBRN 199 212 .
Helen Kelly, Cordelia E M Coltart, Nitika Pant Pai, Jeffrey D Klausner, Magnus Unemo, Igor Toskin & Rosanna W Peeling. (2017) Systematic reviews of point-of-care tests for the diagnosis of urogenital Chlamydia trachomatis infections . Sexually Transmitted Infections 93:S4, pages S22-S30.
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Pouria Amirian, Francois van Loggerenberg, Trudie Lang, Arthur Thomas, Rosanna Peeling, Anahid Basiri & Steven N. Goodman. (2017) Using big data analytics to extract disease surveillance information from point of care diagnostic machines. Pervasive and Mobile Computing 42, pages 470-486.
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Mohammad Zarei. (2017) Advances in point-of-care technologies for molecular diagnostics. Biosensors and Bioelectronics 98, pages 494-506.
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Desmond Kuupiel, Vitalis Bawontuo & Tivani Mashamba-Thompson. (2017) Improving the Accessibility and Efficiency of Point-of-Care Diagnostics Services in Low- and Middle-Income Countries: Lean and Agile Supply Chain Management. Diagnostics 7:4, pages 58.
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Rosanna W. Peeling, Debrah I. Boeras, Francesco Marinucci & Philippa Easterbrook. (2017) The future of viral hepatitis testing: innovations in testing technologies and approaches. BMC Infectious Diseases 17:S1.
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J. J. Hirvonen, P. Matero, C. Siebert, J. Kauppila, R. Vuento, H. Tuokko & S. Boisset. (2016) Novel portable platform for molecular detection of toxigenic Clostridium difficile in faeces: a diagnostic accuracy study. European Journal of Clinical Microbiology & Infectious Diseases 36:5, pages 783-789.
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Piero L. Olliaro, Tushar A. K. M. Shamsuzzaman, Baburam Marasini, A. C. Dhariwal, Ahmed Be-Nazir, Dinesh Mondal, Megha Raj Banjara, Pradeep Das, Shyam Sundar, Suman Rijal, Byron Arana, Jorge Alvar, Daniel Argaw, Rosanna W. Peeling, Axel Kroeger & Greg Matlashewski. (2017) Investments in Research and Surveillance Are Needed to Go Beyond Elimination and Stop Transmission of Leishmania in the Indian Subcontinent. PLOS Neglected Tropical Diseases 11:1, pages e0005190.
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Samiksha Nayak, Nicole R. Blumenfeld, Tassaneewan Laksanasopin & Samuel K. Sia. (2016) Point-of-Care Diagnostics: Recent Developments in a Connected Age. Analytical Chemistry 89:1, pages 102-123.
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Rosanna W. Peeling, Debrah I. Boeras & John Nkengasong. (2017) Re-imagining the future of diagnosis of Neglected Tropical Diseases. Computational and Structural Biotechnology Journal 15, pages 271-274.
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Lei Wang, Milena Veselinovic, Lang Yang, Brian J. Geiss, David S. Dandy & Tom Chen. (2017) A sensitive DNA capacitive biosensor using interdigitated electrodes. Biosensors and Bioelectronics 87, pages 646-653.
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Pouria Amirian, Trudie Lang, Francois van Loggerenberg, Arthur Thomas & Rosanna Peeling. 2017. Big Data in Healthcare. Big Data in Healthcare 59 83 .
Rosanna W. Peeling & Piero Olliaro. (2016) Reimagining the Future of the Diagnosis of Viral Infections. Journal of Infectious Diseases 214:6, pages 828-829.
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Steven J. Drews. (2016) The Role of Clinical Virology Laboratory and the Clinical Virology Laboratorian in Ensuring Effective Surveillance for Influenza and Other Respiratory Viruses: Points to Consider and Pitfalls to Avoid. Current Treatment Options in Infectious Diseases 8:3, pages 165-176.
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Luc Bissonnette & Michel Bergeron. (2016) The GenePOC Platform, a Rational Solution for Extreme Point-of-Care Testing. Micromachines 7:6, pages 94.
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Katherine E. McCracken & Jeong-Yeol Yoon. (2016) Recent approaches for optical smartphone sensing in resource-limited settings: a brief review. Analytical Methods 8:36, pages 6591-6601.
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R. W. Peeling. (2015) Diagnostics in a digital age: an opportunity to strengthen health systems and improve health outcomes. International Health 7:6, pages 384-389.
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Ruth McNerney & Rosanna W. Peeling. (2015) Regulatory In Vitro Diagnostics Landscape in Africa: Update on Regional Activities. Clinical Infectious Diseases 61:suppl 3, pages S135-S140.
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Ruth McNerney. (2015) Diagnostics for Developing Countries. Diagnostics 5:2, pages 200-209.
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Ruth McNerney, Jane Cunningham, Pamela Hepple & Alimuddin Zumla. (2015) New tuberculosis diagnostics and rollout. International Journal of Infectious Diseases 32, pages 81-86.
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Luc Bissonnette & Michel G. Bergeron. 2015. Current and Emerging Technologies for the Diagnosis of Microbial Infections. Current and Emerging Technologies for the Diagnosis of Microbial Infections 87 110 .
Wendy Stevens, Natasha Gous, Nathan Ford & Lesley E Scott. (2014) Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions. BMC Medicine 12:1.
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Simon Peter Rugera, Ruth McNerney, Albert K Poon, Gladys Akimana, Rehema Forgen Mariki, Henry Kajumbula, Elizabeth Kamau, Servilien Mpawenimana, Said Yusuf Said, Anthony Toroitich, Wesley Ronoh, Kimberly A Sollis, Stanley Sonoiya & Rosanna W Peeling. (2014) Regulation of medical diagnostics and medical devices in the East African community partner states. BMC Health Services Research 14:1.
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